AutismKB 2.0

Annotation Detail for UBE3B


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Basic Information Top
Gene Symbol:UBE3B ( DKFZp586K2123,DKFZp686A1051,FLJ45294,MGC131858,MGC78388 )
Gene Full Name: ubiquitin protein ligase E3B
Band: 12q24.11
Quick LinksEntrez ID:89910; OMIM: 608047; Uniprot ID:UBE3B_HUMAN; ENSEMBL ID: ENSG00000151148; HGNC ID: 13478
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
419Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
102Phosphoserine(IKK)HMM predict
168O-linkedHMM predict
265Phosphothreonine(CDK)HMM predict
271Phosphothreonine(CDK)HMM predict
271Phosphothreonine(MAPK)HMM predict
271Phosphothreonine(CDC2)HMM predict
323Phosphoserine(MAPK)HMM predict
350Phosphoserine(ATM)HMM predict
355N-linkedHMM predict
409Phosphoserine(ATM)HMM predict
419Phosphoserine(CDC2)HMM predict
439PhosphoserineHMM predict
454Phosphoserine(PKA)HMM predict
517N-linkedHMM predict
533S-palmitoylHMM predict
611Phosphothreonine(PKA)HMM predict
674O-linkedHMM predict
675O-linkedHMM predict
695Phosphotyrosine(Syk)HMM predict
702Phosphoserine(ATM)HMM predict
762Phosphoserine(CDC2)HMM predict
821Phosphoserine(MAPK)HMM predict
827Phosphotyrosine(Syk)HMM predict
829N-linkedHMM predict
894N-linkedHMM predict
1044N-linkedHMM predict
1045Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_130466
  • Location:chr12 108399821-108458888
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 108399276 108400258 982 55
P300 T30-glioblastomaGSE21026 108399273 108400343 1070 14
Rb GrowingGSE19898 108399689 108399895 206 30
Rb QuiescentGSE19898 108399624 108399920 296 50
Rb SenescentGSE19898 108399592 108400024 432 14
p130 shRbQuiescentGSE19898 108399125 108400269 1144 125
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 108459172 108459841 669 618
CTCF G2GSE9613 108463136 108463437 301 4398
CTCF G2GSE9613 108467950 108468201 251 9187
Rb GrowingGSE19898 108464222 108464352 130 5399
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 108440986 108441260 274 0
CTCF CD4SISSRdata 108440986 108441260 274 0
CTCF HelaGSE12889 108440954 108441193 239 0
CTCF G2GSE9613 108423024 108423334 310 0
CTCF G2GSE9613 108433765 108434157 392 0
CTCF G2GSE9613 108440082 108440254 172 0
CTCF G2GSE9613 108440586 108441543 957 0
CTCF G2GSE9613 108444123 108444663 540 0
CTCF G2GSE9613 108445269 108445517 248 0
CTCF G2GSE9613 108447210 108447485 275 0
CTCF G2GSE9613 108455231 108456202 971 0
CTCF G2GSE9613 108457539 108458295 756 0
ER E2-MCF7GSE14664 108437468 108437566 98 0
ER E2-MCF7GSE14664 108451758 108451908 150 0
ER Fulvestrant-MCF7GSE14664 108454231 108454344 113 0
GABP HelaGSE8489 108400984 108401235 251 0
GABP k562GSE8489 108400984 108401438 454 0
GABP k562GSE8489 108401740 108402360 620 0
GATA3 MCF7GSE15244 108419875 108420468 593 0
H3K4me3 colorectalcancer 108400109 108400637 528 0
NRSF pAbJurkat 108443779 108444219 440 0
Oct1 H2O2-HelaGSE14283 108458815 108458842 27 0
PHF8 HeLaGSE20725 108399241 108400464 1223 0
RNAII Tamoxifen-MCF7GSE14664 108415545 108415637 92 0
Rb QuiescentGSE19898 108430205 108430403 198 0
Rb shRbSenescenceGSE19898 108399818 108400037 219 0
TAF HelaGSE8489 108400984 108401198 214 0
TAF k562GSE8489 108400984 108402360 1376 0
hScc1 G2GSE9613 108433765 108434488 723 0
hScc1 G2GSE9613 108440586 108441235 649 0
p130 QuiescentGSE19898 108399685 108400106 421 0
p130 shRbSenescentGSE19898 108399641 108400362 721 0
p63 keratinocytesGSE17611 108419561 108420593 1032 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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