AutismKB 2.0

Annotation Detail for KCNH7


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Basic Information Top
Gene Symbol:KCNH7 ( ERG3,HERG3,Kv11.3,MGC45986 )
Gene Full Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Band: 2q24.2
Quick LinksEntrez ID:90134; OMIM: 608169; Uniprot ID:KCNH7_HUMAN; ENSEMBL ID: ENSG00000184611; HGNC ID: 18863
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
349Phosphoserine.
350Phosphoserine.
353Phosphoserine.
600N-linked (GlcNAc...) (Potential).
632Selectivity filter (By similarity).
Location(AA) Modifications Resource
600N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
74Phosphothreonine(PKC)HMM predict
102N-linkedHMM predict
140Phosphothreonine(MAPK)HMM predict
140Phosphothreonine(CDC2)HMM predict
174Phosphoserine(PKG)HMM predict
174PhosphoserineHMM predict
191Phosphoserine(PKA)HMM predict
202Phosphoserine(CDC2)HMM predict
207Phosphoserine(PKA)HMM predict
209Phosphoserine(ATM)HMM predict
211Phosphoserine(CK2)HMM predict
230N-linkedHMM predict
256Phosphoserine(ATM)HMM predict
274Phosphoserine(PKA)HMM predict
274Phosphoserine(PKA)HMM predict
274Phosphoserine(PKG)HMM predict
275Phosphoserine(PKB)HMM predict
326Phosphotyrosine(INSR)HMM predict
338N-linkedHMM predict
348N-linkedHMM predict
349PhosphoserineHMM predict
350Phosphoserine(PKA)HMM predict
353Phosphoserine(CDC2)HMM predict
354Phosphoserine(ATM)HMM predict
369N-linkedHMM predict
446Phosphotyrosine(Jak)HMM predict
545Phosphoserine(CK1)HMM predict
600N-linkedHMM predict
604Phosphoserine(CK1)HMM predict
606Phosphoserine(CK1)HMM predict
606Phosphoserine(ATM)HMM predict
736N-linkedHMM predict
742N-linkedHMM predict
848Phosphotyrosine(EGFR)HMM predict
879Phosphoserine(IKK)HMM predict
881N-linkedHMM predict
887N-linkedHMM predict
896Phosphoserine(PKG)HMM predict
896Phosphoserine(PKA)HMM predict
899Phosphoserine(CK2)HMM predict
905N-linkedHMM predict
908N-linkedHMM predict
916Phosphothreonine(PKC)HMM predict
922Phosphoserine(CDK)HMM predict
936Phosphoserine(PKB)HMM predict
936Phosphoserine(IKK)HMM predict
939Phosphoserine(CK2)HMM predict
1007Phosphoserine(CK1)HMM predict
1008Phosphoserine(IKK)HMM predict
1024Phosphoserine(CK1)HMM predict
1028Phosphotyrosine(SRC)HMM predict
1080Phosphotyrosine(EGFR)HMM predict
1091Phosphoserine(PKG)HMM predict
1091Phosphoserine(ATM)HMM predict
1104Phosphoserine(CDC2)HMM predict
1104Phosphoserine(CK1)HMM predict
1104Phosphoserine(CDK)HMM predict
1107Phosphoserine(CK2)HMM predict
1107Phosphoserine(ATM)HMM predict
1125Phosphoserine(PKG)HMM predict
1127Phosphoserine(CK1)HMM predict
1139N-linkedHMM predict
1151Phosphoserine(CK1)HMM predict
1161Phosphothreonine(PKA)HMM predict
1161Phosphothreonine(PKC)HMM predict
1170Phosphoserine(PKB)HMM predict
1174Phosphoserine(IKK)HMM predict
1175O-linkedHMM predict
1175Phosphoserine(CK1)HMM predict
1177Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033272
  • Location:chr2 162936162-163403485
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 162962797 162962838 41 0
ER E2-MCF7GSE14664 162980574 162980623 49 0
ER Fulvestrant-MCF7GSE14664 162962793 162962830 37 0
Nanog ESGSE20650 162954677 162955030 353 0
Nanog hESGSE18292 162954721 162955041 320 0
Oct1 H2O2-HelaGSE14283 162962802 162962829 27 0
Oct1 HelaGSE14283 162948043 162948087 44 0
Oct1 HelaGSE14283 162962787 162962835 48 0
Oct1 HelaGSE14283 162966212 162966286 74 0
p130 SenescentGSE19898 162942896 162943107 211 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018