AutismKB 2.0

Annotation Detail for ZNF622


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF622 ( MGC17552,MGC2485,ZPR9 )
Gene Full Name: zinc finger protein 622
Band: 5p15.1
Quick LinksEntrez ID:90441; OMIM: 608694; Uniprot ID:ZN622_HUMAN; ENSEMBL ID: ENSG00000173545; HGNC ID: 30958
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
276Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
38Phosphoserine(PKA)HMM predict
62Phosphoserine(CK1)HMM predict
143PhosphoserineHMM predict
143Phosphoserine(CDC2)HMM predict
174Phosphoserine(PKC)HMM predict
198Phosphoserine(CK2)HMM predict
198Phosphoserine(CK2)HMM predict
198Phosphoserine(CK1)HMM predict
215Phosphoserine(CK1)HMM predict
215PhosphoserineHMM predict
215Phosphoserine(CK2)HMM predict
272Phosphothreonine(PKC)HMM predict
305S-palmitoylHMM predict
464N-linkedHMM predict
471PhenylalanineHMM predict
472PhenylalanineHMM predict
473PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033414
  • Location:chr5 16504628-16518893
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 16518391 16519539 1148 72
H3K4me2 HCT116GSE10453 16520094 16520401 307 1354
H3ac HepG2E 16520094 16520545 451 1426
TAF HelaGSE8489 16522050 16522447 397 3355
hScc1 CdLSGSE12603 16520365 16520545 180 1562
p130 QuiescentGSE19898 16518605 16519213 608 16
p130 SenescentGSE19898 16518616 16519517 901 173
p130 shRbQuiescentGSE19898 16518665 16519575 910 227
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 16504156 16504188 32 457
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 16509480 16509629 149 0
CTCF G2GSE9613 16508980 16509995 1015 0
CTCF G2GSE9613 16518160 16519067 907 0
GABP k562GSE8489 16515786 16517222 1436 0
GABP k562GSE8489 16517620 16519448 1828 0
H3K4me3 colorectalcancer 16516515 16517144 629 0
H3K4me3 colorectalcancer 16517620 16518231 611 0
H3ac HepG2E 16517620 16518850 1230 0
Oct1 H2O2-HelaGSE14283 16518667 16518721 54 0
Oct1 HelaGSE14283 16518671 16518724 53 0
PHF8 293TGSE20725 16518120 16519573 1453 0
PHF8 HeLaGSE20725 16517818 16519911 2093 0
TAF HelaGSE8489 16517620 16519448 1828 0
TAFII hESGSE17917 16518512 16519203 691 0
hScc1 BcellGSE12603 16509157 16509700 543 0
hScc1 CdLSGSE12603 16509157 16509665 508 0
hScc1 G2GSE9613 16509122 16509995 873 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1119 Unknown pSILAC miR-16 ZNF622 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000173545 n_a n_a n_a "epithelium, lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018