AutismKB 2.0

Annotation Detail for PAPSS2


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Basic Information Top
Gene Symbol:PAPSS2 ( ATPSK2,SK2 )
Gene Full Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Band: 10q23.2-q23.31
Quick LinksEntrez ID:9060; OMIM: 603005; Uniprot ID:PAPS2_HUMAN; ENSEMBL ID: ENSG00000198682; HGNC ID: 8604
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
515PP-motif.
Location(AA) Modifications Resource
Location(AA) Modification Resource
92Phosphoserine(CDC2)HMM predict
182Phosphotyrosine(INSR)HMM predict
182Phosphotyrosine(Jak)HMM predict
182Phosphotyrosine(Syk)HMM predict
187Phosphothreonine(CDC2)HMM predict
187Phosphothreonine(MAPK)HMM predict
195N-linkedHMM predict
334Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001015880
  • Location:chr10 89409455-89497439
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 89393351 89393819 468 15871
CTCF CD4GSE12889 89406305 89406551 246 3028
CTCF CD4SISSRdata 89406305 89406551 246 3028
ER Breast-CancerGSE22609 89406909 89407530 621 2236
FoxA1 MCF7MACSdata 89404011 89404188 177 5356
Nanog hESGSE18292 89402043 89402492 449 7188
Oct1 HelaGSE14283 89403638 89403675 37 5799
RARA MCF7GSE15244 89396373 89396587 214 12976
STAT1 HeLaGSE12782 89400403 89401852 1449 8328
STAT1 HeLaGSE12783 89400403 89401818 1415 8345
STAT1 IFNSISSRdata 89400790 89401571 781 8275
TFAP2C MCF7GSE21234 89404036 89404358 322 5259
hScc1 BcellGSE12603 89406181 89406650 469 3040
hScc1 CdLSGSE12603 89406141 89406723 582 3024
p63 keratinocytesGSE17611 89392448 89393290 842 16587
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 89426523 89426815 292 0
FoxA1 MCF7MACSdata 89455179 89455361 182 0
Myc K562GSE19551 89410580 89410791 211 0
Nanog hESGSE18292 89494020 89494694 674 0
Oct1 HelaGSE14283 89428348 89428389 41 0
RARA MCF7GSE15244 89442969 89444474 1505 0
RARA MCF7GSE15244 89451477 89451792 315 0
RARG MCF7GSE15244 89413968 89414372 404 0
RARG MCF7GSE15244 89451477 89451692 215 0
RARG MCF7GSE15244 89452208 89453468 1260 0
Sox2 hESGSE18292 89494129 89494493 364 0
hScc1 BcellGSE12603 89409707 89409995 288 0
hScc1 BcellGSE12603 89434636 89434776 140 0
hScc1 BcellGSE12603 89484755 89485343 588 0
hScc1 CdLSGSE12603 89484650 89485642 992 0
hScc1 G2GSE9613 89484650 89485642 992 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
315 Unknown MicroArray miR-124 PAPSS2 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000198682 G1-to-S transition n_a n_a "epithelium, squamous cell, macrophage, muscle cell" "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3428 mRNA PAPSS2 chr10 89409607 89496142 133 EST chr10 89359899 89409740Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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