AutismKB 2.0

Annotation Detail for PIAS2


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Basic Information Top
Gene Symbol:PIAS2 ( MGC102682,MIZ1,PIASX,PIASX-ALPHA,PIASX-BETA,SIZ2,ZMIZ4,miz )
Gene Full Name: protein inhibitor of activated STAT, 2
Band: 18q21.1
Quick LinksEntrez ID:9063; OMIM: 603567; Uniprot ID:PIAS2_HUMAN; ENSEMBL ID: ENSG00000078043; HGNC ID: 17311
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
23LXXLL motif.
492Nuclear localization signal (By
Location(AA) Modifications Resource
Location(AA) Modification Resource
29N-linkedHMM predict
31Phosphoserine(PKB)HMM predict
84Phosphoserine(CK1)HMM predict
90Phosphoserine(CDK)HMM predict
90Phosphoserine(CDC2)HMM predict
106O-linkedHMM predict
108O-linkedHMM predict
110O-linkedHMM predict
110Phosphothreonine(CDK)HMM predict
110Phosphothreonine(CDC2)HMM predict
110Phosphothreonine(MAPK)HMM predict
113Phosphoserine(CDC2)HMM predict
113Phosphoserine(CDK)HMM predict
113Phosphoserine(MAPK)HMM predict
113Phosphoserine(IKK)HMM predict
115O-linkedHMM predict
116Phosphoserine(CDC2)HMM predict
116Phosphoserine(IKK)HMM predict
136Phosphoserine(IKK)HMM predict
136O-linkedHMM predict
165Phosphoserine(IKK)HMM predict
226Phosphotyrosine(EGFR)HMM predict
262N-linkedHMM predict
270Phosphoserine(PKG)HMM predict
290Phosphoserine(PKA)HMM predict
300Phosphothreonine(PKA)HMM predict
333O-linkedHMM predict
394Phosphotyrosine(EGFR)HMM predict
423Phosphoserine(IKK)HMM predict
457O-linkedHMM predict
460O-linkedHMM predict
477Phosphoserine(CK2)HMM predict
478Phosphoserine(CK2)HMM predict
478Phosphoserine(ATM)HMM predict
499Phosphoserine(CDC2)HMM predict
499Phosphoserine(CDK)HMM predict
516O-linkedHMM predict
546Phosphoserine(ATM)HMM predict
574Phosphoserine(MAPK)HMM predict
574Phosphoserine(CDC2)HMM predict
574Phosphoserine(CDK)HMM predict
577O-linkedHMM predict
579O-linkedHMM predict
579O-linkedHMM predict
580O-linkedHMM predict
581O-linkedHMM predict
582O-linkedHMM predict
582O-linkedHMM predict
582Phosphoserine(CK1)HMM predict
582Phosphoserine(IKK)HMM predict
584O-linkedHMM predict
586O-linkedHMM predict
588O-linkedHMM predict
591Phosphoserine(CK1)HMM predict
592Phosphoserine(CK1)HMM predict
598Phosphoserine(CK1)HMM predict
602Phosphoserine(CK1)HMM predict
602Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004671
  • Location:chr18 42646058-42751463
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 42636722 42637516 794 8940
CBP T30-glioblastomaGSE21026 42636897 42637489 592 8866
ER E2-MCF7GSE14664 42637495 42637528 33 8547
Myc K562GSE19551 42627553 42627951 398 18307
NRSF mAbJurkat 42638765 42639585 820 6884
Oct1 H2O2-HelaGSE14283 42642163 42642193 30 3881
Oct1 HelaGSE14283 42634307 42634340 33 11735
Oct1 HelaGSE14283 42640205 42640236 31 5838
TAF HelaGSE8489 42638588 42639834 1246 6848
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018