Annotation Detail for ASH2L

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Basic Information Top

Gene Symbol:	ASH2L ( ASH2,ASH2L1,ASH2L2,Bre2 )
Gene Full Name:	ash2 (absent, small, or homeotic)-like (Drosophila)
Band:	8p11.23
Quick Links	Entrez ID:9070; OMIM: 604782; Uniprot ID:ASH2L_HUMAN; ENSEMBL ID: ENSG00000129691; HGNC ID: 744
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

No data

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	38062998	38063232	234	19108
CTCF	CD4	SISSRdata	38062998	38063232	234	19108
CTCF	G2	GSE9613	38081824	38082591	767	15
E2F4	G0	GSE7516	38081390	38082627	1237	214
H3ac	HepG2	E	38081390	38081785	395	635
LIN9	G0	GSE7516	38081390	38082731	1341	162
LIN9	S	GSE7516	38081427	38082662	1235	178
Oct1	H2O2-Hela	GSE14283	38079213	38079240	27	2996
Oct1	Hela	GSE14283	38063864	38063907	43	18337
P300	T30-glioblastoma	GSE21026	38081276	38082780	1504	195
PHF8	293T	GSE20725	38081291	38082899	1608	128
PHF8	HeLa	GSE20725	38081465	38082875	1410	53
PolII	HeLa	GSE12783	38080948	38083174	2226	162
RNAII	Tamoxifen-MCF7	GSE14664	38080379	38080425	46	1821
p130	Quiescent	GSE19898	38081495	38082598	1103	176
p130	shRbQuiescent	GSE19898	38081665	38082777	1112	2
p130	shRbSenescent	GSE19898	38081401	38082679	1278	183
p130	G0	GSE7516	38081390	38082627	1237	214

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	38097365	38097558	193
CTCF	CD4	SISSRdata	38097365	38097558	193
CTCF	G2	GSE9613	38097354	38097676	322
ER	Fulvestrant-MCF7	GSE14664	38088512	38088551	39
H3K4me3	colorectal	cancer	38082515	38083122	607
H3ac	HepG2	E	38082560	38083122	562
H3ac	HepG2	E	38083654	38084776	1122
NRSF	pAb	Jurkat	38082077	38082560	483
Nanog	hES	GSE18292	38084703	38085077	374
Oct1	Hela	GSE14283	38088517	38088552	35
Oct1	Hela	GSE14283	38092550	38092610	60
RNAII	Tamoxifen-MCF7	GSE14664	38104993	38105035	42
Rb	Growing	GSE19898	38082067	38082500	433
Rb	Quiescent	GSE19898	38082058	38082581	523
Sox2	hES	GSE18292	38097171	38097724	553
TAF	Hela	GSE8489	38083654	38084102	448
TAF	k562	GSE8489	38082766	38083122	356
hScc1	Bcell	GSE12603	38082316	38082662	346
hScc1	Bcell	GSE12603	38097354	38097908	554
hScc1	CdLS	GSE12603	38081824	38083122	1298
hScc1	CdLS	GSE12603	38097246	38097676	430
p130	Senescent	GSE19898	38082032	38082647	615
p130	S	GSE7516	38081749	38082731	982

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1136	Unknown	pSILAC	miR-1	ASH2L	down 75-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000129691		n_a	n_a	n_a	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018