AutismKB 2.0

Annotation Detail for ZNF598


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Basic Information Top
Gene Symbol:ZNF598 ( DKFZp762F135,FLJ00086 )
Gene Full Name: zinc finger protein 598
Band: 16p13.3
Quick LinksEntrez ID:90850; OMIM: NA; Uniprot ID:ZN598_HUMAN; ENSEMBL ID: ENSG00000167962; HGNC ID: 28079
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
306Phosphotyrosine.
437Phosphoserine.
Location(AA) Modifications Resource
306Phosphotyrosine.Swiss-Prot 53.0
306PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
211Phosphotyrosine(Jak)HMM predict
224Phosphotyrosine(Syk)HMM predict
225SulfotyrosineHMM predict
225Phosphotyrosine(Syk)HMM predict
306PhosphotyrosineHMM predict
306Phosphotyrosine(EGFR)HMM predict
306Phosphotyrosine(INSR)HMM predict
306Phosphotyrosine(Syk)HMM predict
323Phosphothreonine(PKC)HMM predict
352Phosphoserine(PKG)HMM predict
412Phosphoserine(ATM)HMM predict
417Phosphoserine(CK1)HMM predict
437Phosphoserine(MAPK)HMM predict
447Phosphoserine(IKK)HMM predict
451Phosphoserine(IKK)HMM predict
453O-linkedHMM predict
454Phosphoserine(IKK)HMM predict
458O-linkedHMM predict
461Phosphothreonine(MAPK)HMM predict
476MethylarginineHMM predict
479Phosphoserine(PKB)HMM predict
508N-linkedHMM predict
511Phosphoserine(CDC2)HMM predict
512Phosphoserine(CK1)HMM predict
512Phosphoserine(CDC2)HMM predict
513Phosphoserine(CK1)HMM predict
526O-linkedHMM predict
532Phosphothreonine(PKC)HMM predict
540MethylarginineHMM predict
543MethylarginineHMM predict
570Phosphothreonine(PKA)HMM predict
572O-linkedHMM predict
600O-linkedHMM predict
623O-linkedHMM predict
659O-linkedHMM predict
695O-linkedHMM predict
708O-linkedHMM predict
728Phosphoserine(CDC2)HMM predict
732O-linkedHMM predict
733O-linkedHMM predict
734O-linkedHMM predict
843Phosphothreonine(PKC)HMM predict
904ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_178167
  • Location:chr16 1987768-1999763
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2005895 2006075 180 6222
CTCF G2GSE9613 2006556 2007168 612 7099
ER MCF7GSE19013 2007836 2008409 573 8359
ETS1 JurkatGSE17954 1999482 2000686 1204 321
GABP k562GSE8489 1999912 2000515 603 450
GABP k562GSE8489 2005602 2005895 293 5985
Myc hESGSE17917 1999597 2000247 650 159
PHF8 293TGSE20725 1999211 2000584 1373 134
PHF8 Hs68minusFBSGSE20725 1999485 2000660 1175 309
PHF8 Hs68plusFBSGSE20725 1999157 2000950 1793 290
PolII HeLaGSE12783 2005212 2006271 1059 5978
TFAP2C MCF7GSE21234 2005117 2006230 1113 5910
p130 QuiescentGSE19898 2000064 2000551 487 544
p130 SenescentGSE19898 1999848 2000587 739 454
p130 shRbQuiescentGSE19898 1999926 2000387 461 393
p130 shRbSenescentGSE19898 1999856 2000632 776 481
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1993877 1994156 279 0
CTCF CD4SISSRdata 1993877 1994156 279 0
CTCF G2GSE9613 1987998 1989382 1384 0
CTCF G2GSE9613 1989853 1990092 239 0
CTCF G2GSE9613 1993124 1995893 2769 0
CTCF G2GSE9613 1996575 1996913 338 0
CTCF G2GSE9613 1997381 1997664 283 0
GABP k562GSE8489 1998216 1998739 523 0
Myc K562GSE19551 1993754 1994315 561 0
NRSF mAbJurkat 1992406 1993399 993 0
P300 T0-glioblastomaGSE21026 1987573 1988261 688 0
P300 T30-glioblastomaGSE21026 1987407 1988208 801 0
PHF8 HeLaGSE20725 1998849 2000557 1708 0
Rb GrowingGSE19898 1993875 1994133 258 0
Rb GrowingGSE19898 1998749 1999092 343 0
Rb QuiescentGSE19898 1998759 1999142 383 0
Rb SenescentGSE19898 1998719 1999180 461 0
Rb shRbQuiescentGSE19898 1998891 1999183 292 0
Rb shRbSenescenceGSE19898 1998713 1999125 412 0
hScc1 BcellGSE12603 1993157 1993472 315 0
hScc1 BcellGSE12603 1999159 1999912 753 0
p130 QuiescentGSE19898 1998867 1999155 288 0
p130 SenescentGSE19898 1987758 1987940 182 0
p130 SenescentGSE19898 1998641 1999071 430 0
p130 shRbSenescentGSE19898 1998742 1999021 279 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018