Annotation Detail for DHX57

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Basic Information Top

Gene Symbol:	DHX57 ( DDX57,FLJ32861 )
Gene Full Name:	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Band:	2p22.1
Quick Links	Entrez ID:90957; OMIM: NA; Uniprot ID:DHX57_HUMAN; ENSEMBL ID: ENSG00000163214; HGNC ID: 20086
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	38956160	38956937	777	24

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
STAT1	HeLa	GSE12783	38877524	38878523	999	355
STAT1	IFN	SISSRdata	38877782	38878391	609	292

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	T0-glioblastoma	GSE21026	38925231	38925494	263
CBP	T30-glioblastoma	GSE21026	38925075	38925466	391
CTCF	G2	GSE9613	38956188	38956642	454
FOXA1	MCF7	GSE15244	38943376	38944074	698
GABP	k562	GSE8489	38955463	38956254	791
H3K4me3	colorectal	cancer	38955463	38956254	791
Myc	K562	GSE19551	38908340	38908587	247
Oct1	H2O2-Hela	GSE14283	38955101	38955130	29
Oct1	Hela	GSE14283	38879372	38879410	38
Oct1	Hela	GSE14283	38901909	38901938	29
Oct1	Hela	GSE14283	38909432	38909464	32
Oct1	Hela	GSE14283	38915849	38915882	33
Oct1	Hela	GSE14283	38937891	38937922	31
Oct1	Hela	GSE14283	38955053	38955128	75
P300	T0-glioblastoma	GSE21026	38925280	38925839	559
P300	T30-glioblastoma	GSE21026	38908313	38908816	503
P300	T30-glioblastoma	GSE21026	38925031	38925656	625
PHF8	HeLa	GSE20725	38955862	38956856	994
hScc1	Bcell	GSE12603	38956141	38956473	332
p130	shRbSenescent	GSE19898	38955851	38957102	1251

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
846	Unknown	pSILAC	let-7b	DHX57	down 50-25%	18668040
913	Unknown	pSILAC	LNA_let-7b	DHX57	up <25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000163214		n_a	n_a	n_a	"lymphocyte, squamous cell"	"malignant tumour, carcinoma, benign tumour, sarcoma"
ENSG00000163214		n_a	n_a	n_a	"lymphocyte, squamous cell"	"malignant tumour, carcinoma, benign tumour, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018