AutismKB 2.0

Annotation Detail for ACY3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACY3 ( ACY-3,HCBP1,MGC9740 )
Gene Full Name: aspartoacylase (aminocyclase) 3
Band: 11q13.2
Quick LinksEntrez ID:91703; OMIM: NA; Uniprot ID:ACY3_HUMAN; ENSEMBL ID: ENSG00000132744; HGNC ID: 24104
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
58Phosphothreonine(PKC)HMM predict
70N-linkedHMM predict
88Phosphotyrosine(Jak)HMM predict
88Phosphotyrosine(SRC)HMM predict
88Phosphotyrosine(Syk)HMM predict
117N-linkedHMM predict
121N-linkedHMM predict
272Phosphotyrosine(INSR)HMM predict
312O-linkedHMM predict
312Phosphothreonine(MAPK)HMM predict
317ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_080658
  • Location:chr11 67166602-67174705
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 67176537 67176622 85 1874
Oct1 HelaGSE14283 67180212 67180249 37 5525
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 67165619 67165983 364 802
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 67172180 67172461 281 0
CTCF CD4SISSRdata 67172180 67172461 281 0
TFAP2C MCF7GSE21234 67171991 67172675 684 0
hScc1 BcellGSE12603 67166938 67167181 243 0
hScc1 BcellGSE12603 67168080 67168259 179 0
hScc1 BcellGSE12603 67168807 67169255 448 0
hScc1 BcellGSE12603 67172475 67172828 353 0
hScc1 G2GSE9613 67168080 67168438 358 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018