AutismKB 2.0

Annotation Detail for DCLK1


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Basic Information Top
Gene Symbol:DCLK1 ( CL1,CLICK1,DCAMKL1,DCDC3A,DCLK,KIAA0369 )
Gene Full Name: doublecortin-like kinase 1
Band: 13q13.3
Quick LinksEntrez ID:9201; OMIM: 604742; Uniprot ID:DCLK1_HUMAN; ENSEMBL ID: ENSG00000133083; HGNC ID: 2700
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
32Phosphoserine (By similarity).
36Phosphoserine (By similarity).
305Phosphoserine (By similarity).
307Phosphoserine (By similarity).
330Phosphoserine.
332Phosphoserine.
334Phosphoserine.
336Phosphothreonine.
337Phosphoserine.
364Phosphoserine (By similarity).
376Phosphoserine (By similarity).
493Phosphotyrosine (By similarity).
520Phosphotyrosine (By similarity).
722Phosphoserine (By similarity).
726Phosphoserine (By similarity).
Location(AA) Modifications Resource
305Phosphoserine (By similarity).Swiss-Prot 53.0
307Phosphoserine (By similarity).Swiss-Prot 53.0
332Phosphoserine (By similarity).Swiss-Prot 53.0
336Phosphothreonine (By similarity).Swiss-Prot 53.0
364Phosphoserine (By similarity).Swiss-Prot 53.0
376Phosphoserine (By similarity).Swiss-Prot 53.0
722Phosphoserine (By similarity).Swiss-Prot 53.0
726Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphoserine(CDK)HMM predict
32Phosphoserine(CDC2)HMM predict
118Phosphoserine(CK2)HMM predict
129Phosphotyrosine(INSR)HMM predict
142Phosphotyrosine(INSR)HMM predict
156O-linkedHMM predict
157PhosphothreonineHMM predict
164Phosphoserine(IKK)HMM predict
168O-linkedHMM predict
284Phosphotyrosine(INSR)HMM predict
290Phosphoserine(CDC2)HMM predict
295Phosphothreonine(PKC)HMM predict
295Phosphothreonine(PKA)HMM predict
296Phosphothreonine(PKA)HMM predict
298Phosphoserine(CDC2)HMM predict
298Phosphoserine(CDK)HMM predict
298Phosphoserine(IKK)HMM predict
298PhosphoserineHMM predict
305Phosphoserine(PKA)HMM predict
305Phosphoserine(PKG)HMM predict
305O-linkedHMM predict
307Phosphoserine(CDC2)HMM predict
307Phosphoserine(IKK)HMM predict
307Phosphoserine(PKB)HMM predict
307Phosphoserine(CDK)HMM predict
310Phosphoserine(IKK)HMM predict
311O-linkedHMM predict
312O-linkedHMM predict
312O-linkedHMM predict
313Phosphoserine(IKK)HMM predict
313Phosphoserine(CK1)HMM predict
315N-linkedHMM predict
317Phosphothreonine(MAPK)HMM predict
317Phosphothreonine(CDC2)HMM predict
320Phosphoserine(IKK)HMM predict
324Phosphothreonine(MAPK)HMM predict
330Phosphoserine(CDC2)HMM predict
330O-linkedHMM predict
330Phosphoserine(IKK)HMM predict
332Phosphoserine(IKK)HMM predict
332Phosphoserine(CDC2)HMM predict
334O-linkedHMM predict
334Phosphoserine(CDC2)HMM predict
334Phosphoserine(ATM)HMM predict
336O-linkedHMM predict
336O-linkedHMM predict
337Phosphoserine(IKK)HMM predict
337Phosphoserine(MAPK)HMM predict
337Phosphoserine(CDC2)HMM predict
340Phosphoserine(CDK)HMM predict
347Phosphoserine(ATM)HMM predict
354O-linkedHMM predict
355O-linkedHMM predict
355Phosphoserine(IKK)HMM predict
358O-linkedHMM predict
364Phosphoserine(IKK)HMM predict
390Phosphotyrosine(Jak)HMM predict
412Phosphothreonine(PKC)HMM predict
546O-linkedHMM predict
553Phosphotyrosine(SRC)HMM predict
676N-linkedHMM predict
720Phosphoserine(CK1)HMM predict
725Phosphotyrosine(Syk)HMM predict
725Phosphotyrosine(INSR)HMM predict
725SulfotyrosineHMM predict
726Phosphoserine(IKK)HMM predict
726Phosphoserine(ATM)HMM predict
732Phosphothreonine(PKC)HMM predict
732O-linkedHMM predict
735Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004734
  • Location:chr13 35243477-35603442
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 35614932 35615263 331 11655
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 35546500 35546821 321 0
CBP T30-glioblastomaGSE21026 35546607 35546794 187 0
CBP T30-glioblastomaGSE21026 35596211 35596982 771 0
CTCF CD4GSE12889 35450734 35450930 196 0
CTCF CD4SISSRdata 35450734 35450930 196 0
CTCF G2GSE9613 35257483 35257742 259 0
CTCF G2GSE9613 35261425 35261607 182 0
CTCF G2GSE9613 35291030 35291223 193 0
CTCF G2GSE9613 35298816 35299191 375 0
CTCF G2GSE9613 35388607 35388936 329 0
CTCF G2GSE9613 35400440 35400620 180 0
CTCF G2GSE9613 35425780 35426114 334 0
CTCF G2GSE9613 35450649 35451034 385 0
CTCF G2GSE9613 35462523 35462700 177 0
CTCF G2GSE9613 35602611 35603746 1135 0
ER E2-MCF7GSE14664 35348777 35348824 47 0
ER Fulvestrant-MCF7GSE14664 35511566 35511608 42 0
ER Fulvestrant-MCF7GSE14664 35527559 35527591 32 0
ER Fulvestrant-MCF7GSE14664 35541191 35541225 34 0
ER Fulvestrant-MCF7GSE14664 35594391 35594430 39 0
ER MCF7GSE19013 35602812 35603407 595 0
FOXA1 MCF7GSE15244 35478339 35479511 1172 0
FOXA1 MCF7GSE15244 35572941 35573683 742 0
FoxA1 MCF7MACSdata 35425724 35425965 241 0
FoxA1 MCF7MACSdata 35478406 35478670 264 0
FoxA1 MCF7MACSdata 35479070 35479278 208 0
KLF4 hESGSE17917 35451405 35451578 173 0
NFkBII GM12878GSE19485 35402295 35403560 1265 0
NRSF JurkatGSE13047 35529117 35529727 610 0
NRSF mAbJurkat 35525855 35526105 250 0
NRSF mAbJurkat 35526594 35527928 1334 0
NRSF mAbJurkat 35529084 35531961 2877 0
NRSF-mono JurkatQuESTdata 35529116 35529711 595 0
NRSF-poly JurkatQuESTdata 35529115 35529727 612 0
Nanog hESGSE18292 35330014 35330582 568 0
Nanog hESGSE18292 35380205 35380692 487 0
Nanog hESGSE18292 35402922 35403434 512 0
Oct1 H2O2-HelaGSE14283 35438162 35438192 30 0
Oct1 H2O2-HelaGSE14283 35521766 35521800 34 0
Oct1 H2O2-HelaGSE14283 35600213 35600243 30 0
Oct1 HelaGSE14283 35314913 35314950 37 0
Oct1 HelaGSE14283 35331020 35331052 32 0
Oct1 HelaGSE14283 35333510 35333546 36 0
Oct1 HelaGSE14283 35337039 35337073 34 0
Oct1 HelaGSE14283 35340212 35340245 33 0
Oct1 HelaGSE14283 35345026 35345066 40 0
Oct1 HelaGSE14283 35348775 35348820 45 0
Oct1 HelaGSE14283 35429395 35429438 43 0
Oct1 HelaGSE14283 35431341 35431376 35 0
Oct1 HelaGSE14283 35498076 35498108 32 0
Oct1 HelaGSE14283 35506014 35506053 39 0
Oct1 HelaGSE14283 35507206 35507240 34 0
Oct1 HelaGSE14283 35518232 35518260 28 0
Oct1 HelaGSE14283 35520748 35520829 81 0
Oct1 HelaGSE14283 35527519 35527595 76 0
Oct1 HelaGSE14283 35541190 35541227 37 0
Oct1 HelaGSE14283 35542063 35542142 79 0
Oct1 HelaGSE14283 35594389 35594437 48 0
Oct1 HelaGSE14283 35600213 35600243 30 0
Oct4 hESGSE21916 35327520 35328325 805 0
P300 T0-glioblastomaGSE21026 35596119 35597032 913 0
P300 T30-glioblastomaGSE21026 35596284 35597032 748 0
RARA MCF7GSE15244 35466366 35467307 941 0
RARA MCF7GSE15244 35478339 35479548 1209 0
RARA MCF7GSE15244 35534796 35535097 301 0
RARA MCF7GSE15244 35572617 35573683 1066 0
RARG MCF7GSE15244 35466517 35467277 760 0
RARG MCF7GSE15244 35478339 35479252 913 0
RARG MCF7GSE15244 35572582 35573683 1101 0
Rb shRbQuiescentGSE19898 35390411 35390604 193 0
STAT1 HeLaGSE12783 35500400 35501603 1203 0
TFAP2C MCF7GSE21234 35479019 35479426 407 0
VDR GM10855-stimGSE22484 35517890 35519766 1876 0
VDR GM10861-stimGSE22484 35518274 35519477 1203 0
hScc1 BcellGSE12603 35450649 35451647 998 0
hScc1 BcellGSE12603 35602684 35603443 759 0
hScc1 CdLSGSE12603 35450649 35451295 646 0
hScc1 G2GSE9613 35450649 35451511 862 0
p130 QuiescentGSE19898 35399647 35399818 171 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7066 HTC chr13 35330217 35375094 44877 mRNA DCAMKL1 chr13 35243477 35603443 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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