AutismKB 2.0

Annotation Detail for DLGAP2


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Basic Information Top
Gene Symbol:DLGAP2 ( DAP2,SAPAP2 )
Gene Full Name: discs, large (Drosophila) homolog-associated protein 2
Band: 8p23.3
Quick LinksEntrez ID:9228; OMIM: 605438; Uniprot ID:DLGP2_HUMAN; ENSEMBL ID: ENSG00000198010; HGNC ID: 2906
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
224Phosphoserine (By similarity).
308Phosphotyrosine (By similarity).
436Phosphoserine (By similarity).
446Phosphoserine (By similarity).
449Phosphoserine (By similarity).
570Phosphoserine (By similarity).
740Phosphoserine (By similarity).
1007Phosphoserine (By similarity).
1035Phosphoserine (By similarity).
1042Phosphoserine (By similarity).
Location(AA) Modifications Resource
189Phosphoserine (By similarity).Swiss-Prot 53.0
401Phosphoserine (By similarity).Swiss-Prot 53.0
411Phosphoserine (By similarity).Swiss-Prot 53.0
414Phosphoserine (By similarity).Swiss-Prot 53.0
535Phosphoserine (By similarity).Swiss-Prot 53.0
705Phosphoserine (By similarity).Swiss-Prot 53.0
972Phosphoserine (By similarity).Swiss-Prot 53.0
1000Phosphoserine (By similarity).Swiss-Prot 53.0
1007Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
25SulfotyrosineHMM predict
38Phosphotyrosine(SRC)HMM predict
38Phosphotyrosine(EGFR)HMM predict
46O-linkedHMM predict
87Phosphoserine(CDC2)HMM predict
100Phosphoserine(MAPK)HMM predict
104Phosphoserine(CK1)HMM predict
134Phosphotyrosine(Syk)HMM predict
134SulfotyrosineHMM predict
189Phosphoserine(CDC2)HMM predict
205Phosphothreonine(PKC)HMM predict
209Phosphoserine(CK1)HMM predict
209Phosphoserine(IKK)HMM predict
219N-linkedHMM predict
242Phosphoserine(PKA)HMM predict
271Phosphoserine(CK1)HMM predict
273Phosphotyrosine(Syk)HMM predict
273Phosphotyrosine(INSR)HMM predict
277Phosphoserine(PKC)HMM predict
324Phosphothreonine(MAPK)HMM predict
329Phosphotyrosine(Jak)HMM predict
336Phosphoserine(IKK)HMM predict
337O-linkedHMM predict
341Phosphoserine(ATM)HMM predict
411Phosphoserine(ATM)HMM predict
411Phosphoserine(CK2)HMM predict
414Phosphoserine(ATM)HMM predict
416O-linkedHMM predict
417O-linkedHMM predict
417Phosphoserine(IKK)HMM predict
417Phosphoserine(ATM)HMM predict
421Phosphoserine(CDC2)HMM predict
467Phosphotyrosine(Abl)HMM predict
469Phosphoserine(CDC2)HMM predict
484Phosphoserine(IKK)HMM predict
484Phosphoserine(PKG)HMM predict
490Phosphoserine(IKK)HMM predict
493Phosphoserine(IKK)HMM predict
496Phosphoserine(CK2)HMM predict
506Phosphoserine(IKK)HMM predict
513Phosphoserine(CK1)HMM predict
545Phosphoserine(ATM)HMM predict
545Phosphoserine(CK2)HMM predict
561O-linkedHMM predict
566O-linkedHMM predict
570Phosphoserine(PKG)HMM predict
574Phosphotyrosine(Syk)HMM predict
586O-linkedHMM predict
586O-linkedHMM predict
586Phosphothreonine(PKC)HMM predict
606SulfotyrosineHMM predict
626N-linkedHMM predict
630Phosphoserine(IKK)HMM predict
653O-linkedHMM predict
653Phosphoserine(ATM)HMM predict
653Phosphoserine(IKK)HMM predict
656Phosphoserine(CK1)HMM predict
657O-linkedHMM predict
657Phosphoserine(IKK)HMM predict
680Phosphoserine(IKK)HMM predict
680Phosphoserine(CK1)HMM predict
736Phosphoserine(PKA)HMM predict
771Phosphoserine(IKK)HMM predict
774Phosphoserine(CK1)HMM predict
774O-linkedHMM predict
775Phosphothreonine(MAPK)HMM predict
779Phosphotyrosine(SRC)HMM predict
803O-linkedHMM predict
863Phosphoserine(CK1)HMM predict
906Phosphoserine(IKK)HMM predict
1000Phosphoserine(PKG)HMM predict
1002Phosphoserine(CK2)HMM predict
1007Phosphoserine(CK1)HMM predict
1007Phosphoserine(PKG)HMM predict
1011SulfotyrosineHMM predict
1011Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004745
  • Location:chr8 1436975-1644046
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1418145 1419704 1559 18051
CTCF G2GSE9613 1421095 1421285 190 15786
CTCF G2GSE9613 1430328 1431132 804 6246
CTCF G2GSE9613 1434335 1434621 286 2498
CTCF G2GSE9613 1435964 1436197 233 895
NRSF pAbJurkat 1418630 1419318 688 18002
hScc1 G2GSE9613 1418224 1418782 558 18473
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1631485 1631598 113 0
CTCF CD4GSE12889 1636933 1637159 226 0
CTCF CD4SISSRdata 1631485 1631598 113 0
CTCF CD4SISSRdata 1636933 1637159 226 0
CTCF G2GSE9613 1448532 1448711 179 0
CTCF G2GSE9613 1450260 1450915 655 0
CTCF G2GSE9613 1458932 1459183 251 0
CTCF G2GSE9613 1463816 1464234 418 0
CTCF G2GSE9613 1475186 1475834 648 0
CTCF G2GSE9613 1482387 1483249 862 0
CTCF G2GSE9613 1484372 1485283 911 0
CTCF G2GSE9613 1492891 1493195 304 0
CTCF G2GSE9613 1493534 1493811 277 0
CTCF G2GSE9613 1497399 1497748 349 0
CTCF G2GSE9613 1498696 1499196 500 0
CTCF G2GSE9613 1500325 1500644 319 0
CTCF G2GSE9613 1503552 1504671 1119 0
CTCF G2GSE9613 1506296 1507086 790 0
CTCF G2GSE9613 1516313 1517802 1489 0
CTCF G2GSE9613 1538939 1539585 646 0
CTCF G2GSE9613 1550672 1550848 176 0
CTCF G2GSE9613 1556736 1557041 305 0
CTCF G2GSE9613 1558829 1559149 320 0
CTCF G2GSE9613 1561888 1562369 481 0
CTCF G2GSE9613 1573449 1573718 269 0
CTCF G2GSE9613 1574736 1575116 380 0
CTCF G2GSE9613 1582416 1582796 380 0
CTCF G2GSE9613 1603907 1604272 365 0
CTCF G2GSE9613 1606030 1606202 172 0
CTCF G2GSE9613 1623563 1623936 373 0
CTCF G2GSE9613 1625203 1625374 171 0
CTCF G2GSE9613 1627639 1628012 373 0
CTCF G2GSE9613 1630060 1630991 931 0
CTCF G2GSE9613 1631238 1631767 529 0
CTCF G2GSE9613 1632091 1632348 257 0
CTCF G2GSE9613 1632704 1632975 271 0
CTCF G2GSE9613 1636430 1637110 680 0
ER Breast-CancerGSE22609 1558817 1559327 510 0
ER MCF7GSE19013 1558621 1559369 748 0
FOXA1 MCF7GSE15244 1497997 1498549 552 0
FOXA1 MCF7GSE15244 1625449 1625622 173 0
GABP HelaGSE8489 1446685 1447334 649 0
GABP k562GSE8489 1516313 1517802 1489 0
IGF1R DFBGSE23792 1606477 1606913 436 0
NRSF JurkatGSE13047 1473291 1473873 582 0
NRSF JurkatSISSRdata 1482684 1482871 187 0
NRSF-mono JurkatQuESTdata 1473425 1473788 363 0
NRSF pAbJurkat 1450322 1450457 135 0
NRSF pAbJurkat 1475430 1476139 709 0
NRSF pAbJurkat 1497327 1497960 633 0
NRSF pAbJurkat 1498480 1498992 512 0
NRSF pAbJurkat 1507981 1508449 468 0
NRSF pAbJurkat 1516313 1517802 1489 0
NRSF pAbJurkat 1561693 1561853 160 0
NRSF pAbJurkat 1577578 1580006 2428 0
NRSF pAbJurkat 1605069 1606068 999 0
NRSF pAbJurkat 1627425 1628081 656 0
NRSF-poly JurkatQuESTdata 1473452 1473846 394 0
Nanog hESGSE18292 1469851 1470031 180 0
Nanog hESGSE18292 1514489 1514896 407 0
Oct4 hESGSE17917 1443911 1444138 227 0
Oct4 hESGSE17917 1526851 1527052 201 0
RARA MCF7GSE15244 1633667 1634677 1010 0
Rb shRbSenescenceGSE19898 1583462 1583693 231 0
TAF HelaGSE8489 1516313 1517802 1489 0
c MYCMCF7 1497220 1499063 1843 0
hScc1 BcellGSE12603 1483141 1483432 291 0
hScc1 BcellGSE12603 1484749 1485283 534 0
hScc1 BcellGSE12603 1578572 1580118 1546 0
hScc1 BcellGSE12603 1613842 1614081 239 0
hScc1 BcellGSE12603 1636662 1637110 448 0
hScc1 CdLSGSE12603 1631370 1631767 397 0
hScc1 G2GSE9613 1630060 1631767 1707 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24971 mRNA DLGAP2 chr8 1436975 1644047 56 EST chr8 1501081 1555348Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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