AutismKB 2.0

Annotation Detail for DLG5


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Basic Information Top
Gene Symbol:DLG5 ( KIAA0583,LP-DLG,P-DLG5,PDLG )
Gene Full Name: discs, large homolog 5 (Drosophila)
Band: 10q22.3
Quick LinksEntrez ID:9231; OMIM: 604090; Uniprot ID:DLG5_HUMAN; ENSEMBL ID: ENSG00000151208; HGNC ID: 2904
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
132Phosphoserine.
984Phosphothreonine.
1000Phosphoserine.
1011Phosphothreonine.
1209Phosphoserine.
1263Phosphoserine.
Location(AA) Modifications Resource
874Phosphothreonine.Swiss-Prot 53.0
874PhosphothreoninePhospho.ELM 6.0
890Phosphoserine.Swiss-Prot 53.0
890PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
8Phosphoserine(CK1)HMM predict
10O-linkedHMM predict
10Phosphoserine(CK1)HMM predict
10Phosphoserine(IKK)HMM predict
12Phosphoserine(CK1)HMM predict
12Phosphoserine(IKK)HMM predict
16O-linkedHMM predict
17O-linkedHMM predict
22O-linkedHMM predict
22Phosphoserine(PKA)HMM predict
183N-linkedHMM predict
319Phosphotyrosine(SRC)HMM predict
341Phosphothreonine(PKC)HMM predict
355Phosphoserine(PKC)HMM predict
446Phosphoserine(CK2)HMM predict
478Phosphoserine(ATM)HMM predict
601Phosphoserine(PKG)HMM predict
608Phosphothreonine(MAPK)HMM predict
613N-linkedHMM predict
629Phosphotyrosine(SRC)HMM predict
637Phosphoserine(CDC2)HMM predict
637Phosphoserine(MAPK)HMM predict
637Phosphoserine(CDK)HMM predict
661N-linkedHMM predict
665N-linkedHMM predict
669Phosphoserine(CK1)HMM predict
691Phosphoserine(IKK)HMM predict
729N-linkedHMM predict
730N-linkedHMM predict
754O-linkedHMM predict
783PhosphoserineHMM predict
831Phosphoserine(CK1)HMM predict
844O-linkedHMM predict
874Phosphothreonine(MAPK)HMM predict
874Phosphothreonine(CDK)HMM predict
890O-linkedHMM predict
890Phosphoserine(CDC2)HMM predict
890Phosphoserine(ATM)HMM predict
901Phosphothreonine(MAPK)HMM predict
901Phosphothreonine(CDK)HMM predict
901PhosphothreonineHMM predict
920Phosphothreonine(PKC)HMM predict
922Phosphoserine(CK1)HMM predict
931O-linkedHMM predict
932O-linkedHMM predict
932Phosphoserine(CDC2)HMM predict
934O-linkedHMM predict
934O-linkedHMM predict
935O-linkedHMM predict
936Phosphoserine(ATM)HMM predict
939O-linkedHMM predict
983Phosphoserine(IKK)HMM predict
990Phosphoserine(ATM)HMM predict
1054Phosphoserine(IKK)HMM predict
1067Phosphothreonine(PKC)HMM predict
1071O-linkedHMM predict
1073Phosphothreonine(MAPK)HMM predict
1073Phosphothreonine(CDK)HMM predict
1077O-linkedHMM predict
1153Phosphoserine(PKA)HMM predict
1183Phosphoserine(CK1)HMM predict
1187Phosphoserine(IKK)HMM predict
1191O-linkedHMM predict
1191PhosphothreonineHMM predict
1203Phosphoserine(IKK)HMM predict
1206Phosphoserine(ATM)HMM predict
1208O-linkedHMM predict
1210O-linkedHMM predict
1211O-linkedHMM predict
1234Phosphotyrosine(Jak)HMM predict
1263Phosphotyrosine(EGFR)HMM predict
1263Phosphotyrosine(INSR)HMM predict
1330Phosphoserine(CK1)HMM predict
1331Phosphoserine(CK1)HMM predict
1331Phosphoserine(CK2)HMM predict
1332Phosphoserine(IKK)HMM predict
1346Phosphoserine(IKK)HMM predict
1348O-linkedHMM predict
1350O-linkedHMM predict
1350Phosphothreonine(CDC2)HMM predict
1350Phosphothreonine(MAPK)HMM predict
1350Phosphothreonine(CDK)HMM predict
1368O-linkedHMM predict
1369Phosphothreonine(MAPK)HMM predict
1369PhosphothreonineHMM predict
1447N-linkedHMM predict
1449Phosphothreonine(PKC)HMM predict
1454Phosphotyrosine(EGFR)HMM predict
1454PhosphotyrosineHMM predict
1487Phosphotyrosine(EGFR)HMM predict
1556Phosphoserine(PKA)HMM predict
1556Phosphoserine(PKG)HMM predict
1556Phosphoserine(CAMK2)HMM predict
1556Phosphoserine(IKK)HMM predict
1590Phosphoserine(CAMK2)HMM predict
1603Phosphoserine(CK1)HMM predict
1691O-linkedHMM predict
1752Phosphothreonine(PKA)HMM predict
1752Phosphothreonine(PKC)HMM predict
1785Phosphoserine(IKK)HMM predict
1794ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004747
  • Location:chr10 79220556-79356353
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb GrowingGSE19898 79374388 79374542 154 18112
TFAP2C MCF7GSE21234 79372831 79373566 735 16845
p63 keratinocytesGSE17611 79361623 79362435 812 5676
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb shRbQuiescentGSE19898 79203962 79204137 175 16507
Rb shRbSenescenceGSE19898 79201348 79201544 196 19111
hScc1 BcellGSE12603 79209921 79210695 774 10249
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 79276477 79276686 209 0
CTCF CD4SISSRdata 79276477 79276686 209 0
CTCF HelaGSE12889 79276517 79276717 200 0
CTCF JurkatGSE12889 79276474 79276651 177 0
CTCF JurkatGSE12889 79319940 79320105 165 0
CTCF JurkatGSE12889 79337743 79337904 161 0
ER Fulvestrant-MCF7GSE14664 79279425 79279460 35 0
ER MCF7GSE19013 79299589 79300217 628 0
ER MCF7GSE19013 79301682 79302862 1180 0
ER MCF7GSE19013 79303059 79303504 445 0
ER MCF7GSE19013 79311324 79312070 746 0
ER MCF7GSE19013 79318776 79319816 1040 0
FoxA1 MCF7MACSdata 79289248 79289523 275 0
FoxA1 MCF7MACSdata 79349416 79349732 316 0
H3ac HepG2E 79318131 79319167 1036 0
H3ac HepG2E 79321247 79322200 953 0
H3ac HepG2E 79353928 79355774 1846 0
Oct1 H2O2-HelaGSE14283 79228585 79228617 32 0
Oct1 H2O2-HelaGSE14283 79275273 79275305 32 0
Oct1 HelaGSE14283 79228587 79228617 30 0
Oct1 HelaGSE14283 79275272 79275309 37 0
Oct1 HelaGSE14283 79307335 79307371 36 0
Oct1 HelaGSE14283 79307791 79307819 28 0
Oct1 HelaGSE14283 79318675 79318710 35 0
Oct1 HelaGSE14283 79354763 79354804 41 0
P300 T30-glioblastomaGSE21026 79274519 79275755 1236 0
RARA MCF7GSE15244 79286892 79287726 834 0
RARA MCF7GSE15244 79294768 79296526 1758 0
RARA MCF7GSE15244 79318306 79320039 1733 0
RARA MCF7GSE15244 79320477 79320645 168 0
RARA MCF7GSE15244 79341220 79341631 411 0
RARA MCF7GSE15244 79349018 79350290 1272 0
RARG MCF7GSE15244 79286827 79287726 899 0
RARG MCF7GSE15244 79295007 79297235 2228 0
RARG MCF7GSE15244 79309773 79309910 137 0
RARG MCF7GSE15244 79318269 79320039 1770 0
RARG MCF7GSE15244 79323312 79323875 563 0
RARG MCF7GSE15244 79339755 79340333 578 0
RARG MCF7GSE15244 79341220 79341631 411 0
RARG MCF7GSE15244 79349018 79349977 959 0
RNAII Tamoxifen-MCF7GSE14664 79349428 79349525 97 0
Rb GrowingGSE19898 79296598 79296788 190 0
Rb QuiescentGSE19898 79292206 79292321 115 0
Rb QuiescentGSE19898 79355957 79356192 235 0
Rb SenescentGSE19898 79276501 79276878 377 0
TAF k562GSE8489 79348245 79348635 390 0
TAF k562GSE8489 79354554 79355419 865 0
TFAP2C MCF7GSE21234 79255704 79256269 565 0
TFAP2C MCF7GSE21234 79278789 79279396 607 0
TFAP2C MCF7GSE21234 79280588 79281144 556 0
TFAP2C MCF7GSE21234 79286437 79287860 1423 0
TFAP2C MCF7GSE21234 79295349 79296178 829 0
TFAP2C MCF7GSE21234 79300902 79301191 289 0
TFAP2C MCF7GSE21234 79301833 79303407 1574 0
TFAP2C MCF7GSE21234 79317546 79318130 584 0
TFAP2C MCF7GSE21234 79328784 79329380 596 0
USF2 HepG2E 79318447 79319065 618 0
hScc1 BcellGSE12603 79226089 79226775 686 0
hScc1 BcellGSE12603 79264797 79265090 293 0
hScc1 BcellGSE12603 79276472 79276896 424 0
hScc1 BcellGSE12603 79337704 79338329 625 0
hScc1 BcellGSE12603 79355456 79356246 790 0
hScc1 CdLSGSE12603 79267222 79267652 430 0
hScc1 CdLSGSE12603 79276472 79277054 582 0
hScc1 CdLSGSE12603 79337704 79337956 252 0
hScc1 G2GSE9613 79328075 79328566 491 0
p130 SenescentGSE19898 79303694 79303938 244 0
p130 shRbSenescentGSE19898 79276513 79276939 426 0
p63 keratinocytesGSE17611 79327674 79329735 2061 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3346 mRNA chr10 79296638 79299374 67 mRNA DLG5 chr10 79220556 79298959Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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