Annotation Detail for CD8A

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	CD8A ( CD8,Leu2,MAL,p32 )
Gene Full Name:	CD8a molecule
Band:	2p11.2
Quick Links	Entrez ID:925; OMIM: 186910; Uniprot ID:CD8A_HUMAN; ENSEMBL ID: ENSG00000153563; HGNC ID: 1706
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

Top

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:10 results

No data

Location(AA)	Modification	Resource
49	N-linked	HMM predict
74	Phosphoserine(ATM)	HMM predict
86	Phosphothreonine(PKC)	HMM predict
140	O-linked	HMM predict
140	O-linked	HMM predict
151	O-linked	HMM predict
151	O-linked	HMM predict
217	S-farnesyl	HMM predict
220	Proline	HMM predict
221	Valine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001768
Location:chr2 86865239-86871637
strand:-

Upstream the gene:2 results
Downstream the gene:3 results
Inside the gene:4 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3K27me3	colorectal	cancer	86871629	86873108	1479	731
Rb	Growing	GSE19898	86871970	86872123	153	409

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	86864105	86864139	34	1118
ER	Fulvestrant-MCF7	GSE14664	86864104	86864136	32	1120
Oct1	Hela	GSE14283	86864105	86864139	34	1118

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	86866561	86866923	362
CTCF	G2	GSE9613	86870018	86871433	1415
H3K27me3	colorectal	cancer	86870619	86871157	538
hScc1	Bcell	GSE12603	86871030	86871284	254

Validated miRNA targets

Top

miR Walk:86 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7f	hsa-let-7f-1	9	17925868
hsa-let-7f	hsa-let-7f-2	X	17925868
hsa-let-7f	hsa-let-7f-1	9	17925868
hsa-let-7f	hsa-let-7f-2	X	17925868
hsa-miR-1	hsa-mir-1-2	18	20148420
hsa-miR-1	hsa-mir-1-1	20	20148420
hsa-miR-1	hsa-mir-1-2	18	20148420
hsa-miR-1	hsa-mir-1-1	20	20148420
hsa-miR-106a	hsa-mir-106a	X	20089119
hsa-miR-106a	hsa-mir-106a	X	20089119
hsa-miR-106a*	hsa-mir-106a	X	20089119
hsa-miR-106a*	hsa-mir-106a	X	20089119
hsa-miR-125b	hsa-mir-125b-1	11	21118986
hsa-miR-125b	hsa-mir-125b-2	21	21118986
hsa-miR-125b	hsa-mir-125b-1	11	21118986
hsa-miR-125b	hsa-mir-125b-2	21	21118986
hsa-miR-126	hsa-mir-126	9	20148420
hsa-miR-126	hsa-mir-126	9	20148420
hsa-miR-126*	hsa-mir-126	9	20148420
hsa-miR-126*	hsa-mir-126	9	20148420
hsa-miR-142-3p	hsa-mir-142	17	17925868
hsa-miR-142-3p	hsa-mir-142	17	17925868
hsa-miR-142-5p	hsa-mir-142	17	17925868
hsa-miR-142-5p	hsa-mir-142	17	17925868
hsa-miR-150	hsa-mir-150	19	17925868
hsa-miR-150	hsa-mir-150	19	17438277
hsa-miR-150	hsa-mir-150	19	17925868
hsa-miR-150	hsa-mir-150	19	17438277
hsa-miR-150*	hsa-mir-150	19	17925868
hsa-miR-150*	hsa-mir-150	19	17438277
hsa-miR-150*	hsa-mir-150	19	17925868
hsa-miR-150*	hsa-mir-150	19	17438277
hsa-miR-155	hsa-mir-155	21	21304824
hsa-miR-155	hsa-mir-155	21	21304824
hsa-miR-155*	hsa-mir-155	21	21304824
hsa-miR-155*	hsa-mir-155	21	21304824
hsa-miR-15b	hsa-mir-15b	3	17925868
hsa-miR-15b	hsa-mir-15b	3	17925868
hsa-miR-15b*	hsa-mir-15b	3	17925868
hsa-miR-15b*	hsa-mir-15b	3	17925868
hsa-miR-16	hsa-mir-16-1	13	17925868
hsa-miR-16	hsa-mir-16-2	3	17925868
hsa-miR-16	hsa-mir-16-1	13	17925868
hsa-miR-16	hsa-mir-16-2	3	17925868
hsa-miR-17	hsa-mir-17	13	20148420
hsa-miR-17	hsa-mir-17	13	20089119
hsa-miR-17	hsa-mir-17	13	20148420
hsa-miR-17	hsa-mir-17	13	20089119
hsa-miR-17*	hsa-mir-17	13	20148420
hsa-miR-17*	hsa-mir-17	13	20089119
hsa-miR-17*	hsa-mir-17	13	20148420
hsa-miR-17*	hsa-mir-17	13	20089119
hsa-miR-181a	hsa-mir-181a-2	9	18974849
hsa-miR-181a	hsa-mir-181a-1	1	18974849
hsa-miR-181a	hsa-mir-181a-2	9	17344418
hsa-miR-181a	hsa-mir-181a-1	1	17344418
hsa-miR-181a	hsa-mir-181a-2	9	18974849
hsa-miR-181a	hsa-mir-181a-1	1	18974849
hsa-miR-181a	hsa-mir-181a-2	9	17344418
hsa-miR-181a	hsa-mir-181a-1	1	17344418
hsa-miR-181a*	hsa-mir-181a-1	1	18974849
hsa-miR-181a*	hsa-mir-181a-1	1	18974849
hsa-miR-181c	hsa-mir-181c	19	18974849
hsa-miR-181c	hsa-mir-181c	19	18974849
hsa-miR-181c*	hsa-mir-181c	19	18974849
hsa-miR-181c*	hsa-mir-181c	19	18974849
hsa-miR-193a-3p	hsa-mir-193a	17	20148420
hsa-miR-193a-3p	hsa-mir-193a	17	20148420
hsa-miR-193a-5p	hsa-mir-193a	17	20148420
hsa-miR-193a-5p	hsa-mir-193a	17	20148420
hsa-miR-19b	hsa-mir-19b-1	13	20089119
hsa-miR-19b	hsa-mir-19b-2	X	20089119
hsa-miR-19b	hsa-mir-19b-1	13	20089119
hsa-miR-19b	hsa-mir-19b-2	X	20089119
hsa-miR-20a	hsa-mir-20a	13	20089119
hsa-miR-20a	hsa-mir-20a	13	20089119
hsa-miR-20a*	hsa-mir-20a	13	20089119
hsa-miR-20a*	hsa-mir-20a	13	20089119
hsa-miR-21	hsa-mir-21	17	17925868
hsa-miR-21	hsa-mir-21	17	17925868
hsa-miR-21*	hsa-mir-21	17	17925868
hsa-miR-21*	hsa-mir-21	17	17925868
hsa-miR-497	hsa-mir-497	17	20148420
hsa-miR-497	hsa-mir-497	17	20148420
hsa-miR-497*	hsa-mir-497	17	20148420
hsa-miR-497*	hsa-mir-497	17	20148420

Cis-Nats regulation

Top

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for CD8A

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics