AutismKB 2.0

Annotation Detail for STK17B


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Basic Information Top
Gene Symbol:STK17B ( DRAK2 )
Gene Full Name: serine/threonine kinase 17b
Band: 2q32.3
Quick LinksEntrez ID:9262; OMIM: 604727; Uniprot ID:ST17B_HUMAN; ENSEMBL ID: ENSG00000081320; HGNC ID: 11396
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
16O-linkedHMM predict
35Phosphothreonine(PKC)HMM predict
100Phosphotyrosine(Syk)HMM predict
244Phosphotyrosine(Syk)HMM predict
244Phosphotyrosine(Jak)HMM predict
244Phosphotyrosine(INSR)HMM predict
246N-linkedHMM predict
251N-linkedHMM predict
260Phosphoserine(CK1)HMM predict
263Phosphoserine(IKK)HMM predict
263Phosphoserine(ATM)HMM predict
308Phosphoserine(IKK)HMM predict
308Phosphoserine(CK2)HMM predict
308Phosphoserine(CK1)HMM predict
309Phosphoserine(CK1)HMM predict
309Phosphoserine(IKK)HMM predict
309O-linkedHMM predict
310O-linkedHMM predict
310Phosphoserine(CK2)HMM predict
310Phosphoserine(CK1)HMM predict
311Phosphoserine(ATM)HMM predict
311Phosphoserine(CK1)HMM predict
313Phosphothreonine(PKC)HMM predict
317Phosphoserine(IKK)HMM predict
320Phosphoserine(CK1)HMM predict
326Phosphoserine(IKK)HMM predict
329Phosphoserine(IKK)HMM predict
331N-linkedHMM predict
354PhenylalanineHMM predict
355PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004226
  • Location:chr2 196710102-196744519
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 196749795 196750514 719 5635
PHF8 293TGSE20725 196744050 196745044 994 28
Pol2 GM12878GSE19551 196744067 196745172 1105 100
TAFII hESGSE17917 196744377 196744729 352 34
USF1 HepG2E 196744832 196746741 1909 1267
USF1 HepG2E 196747179 196747858 679 2999
hScc1 BcellGSE12603 196748990 196749398 408 4675
hScc1 G2GSE9613 196743942 196745099 1157 1
p130 QuiescentGSE19898 196744422 196744639 217 11
p130 shRbQuiescentGSE19898 196744346 196745002 656 155
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 196696615 196697224 609 13183
Nanog hESGSE18292 196702351 196702511 160 7672
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 196717457 196717855 398 0
CTCF G2GSE9613 196743905 196744525 620 0
H3K4me3 colorectalcancer 196742635 196743834 1199 0
H3ac HepG2E 196743078 196744014 936 0
P300 T30-glioblastomaGSE21026 196733088 196733603 515 0
PHF8 HeLaGSE20725 196743589 196744717 1128 0
TAF HelaGSE8489 196742808 196743805 997 0
TAF k562GSE8489 196742562 196743834 1272 0
USF1 HepG2E 196742916 196744489 1573 0
hScc1 BcellGSE12603 196744279 196744525 246 0
p130 SenescentGSE19898 196744351 196744655 304 0
p130 shRbSenescentGSE19898 196744217 196744693 476 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018