AutismKB 2.0

Annotation Detail for SRSF11


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Basic Information Top
Gene Symbol:SRSF11 ( DKFZp686M13204,FLJ18226,NET2,SFRS11,dJ677H15.2,p54 )
Gene Full Name: serine/arginine-rich splicing factor 11
Band: 1p31.1
Quick LinksEntrez ID:9295; OMIM: 602010; Uniprot ID:SRS11_HUMAN; ENSEMBL ID: ENSG00000116754; HGNC ID: 10782
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
207Phosphoserine.
260Phosphothreonine.
264Phosphoserine.
295Phosphoserine.
297Phosphoserine.
366Phosphoserine.
368Phosphoserine.
370Phosphoserine.
434Phosphoserine.
449Phosphoserine.
483Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004768
  • Location:chr1 70443952-70490270
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 70443330 70444551 1221 12
PHF8 Hs68minusFBSGSE20725 70443263 70444637 1374 3
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 70459685 70460227 542 0
H3K4me3 colorectalcancer 70444346 70444998 652 0
H3ac HepG2E 70444696 70445095 399 0
H3ac HepG2E 70445512 70445805 293 0
H3ac HepG2E 70459263 70459648 385 0
H3ac HepG2E 70460151 70461176 1025 0
PHF8 293TGSE20725 70443217 70444709 1492 0
PHF8 HeLaGSE20725 70459186 70460609 1423 0
PHF8 Hs68plusFBSGSE20725 70443351 70444757 1406 0
PHF8 Hs68plusFBSGSE20725 70459313 70460719 1406 0
TAF k562GSE8489 70444230 70445095 865 0
TAF k562GSE8489 70455742 70456085 343 0
TAF k562GSE8489 70459137 70459539 402 0
TAF k562GSE8489 70459886 70462165 2279 0
TAFII hESGSE17917 70459489 70460227 738 0
hScc1 BcellGSE12603 70459648 70460111 463 0
p130 QuiescentGSE19898 70459773 70459934 161 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
697 mRNA repression TRUE miR-376a-5p SFRS11 in vitro reporter gene assay (Luciferase) 17322061
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000116754 n_a n_a n_a n_a n_a
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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