AutismKB 2.0

Annotation Detail for KCNB2


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Basic Information Top
Gene Symbol:KCNB2 ( KV2.2 )
Gene Full Name: potassium voltage-gated channel, Shab-related subfamily, member 2
Band: 8q21.11
Quick LinksEntrez ID:9312; OMIM: 607738; Uniprot ID:KCNB2_HUMAN; ENSEMBL ID: ENSG00000182674; HGNC ID: 6232
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
287N-linked (GlcNAc...) (Potential).
386Selectivity filter (By similarity).
Location(AA) Modifications Resource
287N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
14Phosphoserine(PKG)HMM predict
87SulfotyrosineHMM predict
137S-palmitoylHMM predict
158Phosphothreonine(PKC)HMM predict
384SulfotyrosineHMM predict
402S-palmitoylHMM predict
446N-linkedHMM predict
448Phosphoserine(IKK)HMM predict
500Phosphoserine(CK2)HMM predict
503Phosphoserine(CK1)HMM predict
512Phosphotyrosine(EGFR)HMM predict
525N-linkedHMM predict
526N-linkedHMM predict
527O-linkedHMM predict
528O-linkedHMM predict
530Phosphoserine(CK1)HMM predict
531Phosphoserine(ATM)HMM predict
554Phosphoserine(IKK)HMM predict
570Phosphotyrosine(EGFR)HMM predict
605Phosphoserine(IKK)HMM predict
605O-linkedHMM predict
619Phosphoserine(CDC2)HMM predict
619Phosphoserine(CDK)HMM predict
619O-linkedHMM predict
625O-linkedHMM predict
695N-linkedHMM predict
699Phosphoserine(CDC2)HMM predict
729Phosphothreonine(CDK)HMM predict
729Phosphothreonine(MAPK)HMM predict
729Phosphothreonine(CDC2)HMM predict
729PhosphothreonineHMM predict
732O-linkedHMM predict
732Phosphoserine(CDC2)HMM predict
732O-linkedHMM predict
733O-linkedHMM predict
733O-linkedHMM predict
745O-linkedHMM predict
747O-linkedHMM predict
762Phosphoserine(ATM)HMM predict
781O-linkedHMM predict
785Phosphoserine(CDC2)HMM predict
785Phosphoserine(CDK)HMM predict
809Phosphothreonine(CK2)HMM predict
853O-linkedHMM predict
854O-linkedHMM predict
855Phosphoserine(CDC2)HMM predict
868Phosphotyrosine(Jak)HMM predict
879Phosphoserine(IKK)HMM predict
903Phosphotyrosine(Jak)HMM predict
904CysteineHMM predict
907ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004770
  • Location:chr8 73612179-74013135
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 73610062 73610347 285 1975
CTCF G2GSE9613 73611491 73612301 810 284
ER E2-MCF7GSE14664 73606544 73606579 35 5618
ER Fulvestrant-MCF7GSE14664 73606541 73606580 39 5619
H3K27me3 colorectalcancer 73610864 73611184 320 1156
NRSF pAbJurkat 73611528 73612301 773 265
Oct1 H2O2-HelaGSE14283 73593879 73593912 33 18284
Oct1 HelaGSE14283 73593873 73593915 42 18286
Oct1 HelaGSE14283 73599834 73599861 27 12332
Oct1 HelaGSE14283 73606543 73606585 42 5616
hScc1 BcellGSE12603 73611362 73612111 749 443
hScc1 CdLSGSE12603 73611578 73612075 497 353
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 74018586 74019353 767 5834
FOXA1 MCF7GSE15244 74019999 74020508 509 7118
NRSF JurkatSISSRdata 74018889 74019074 185 5846
Oct1 HelaGSE14283 74014274 74014311 37 1157
hScc1 BcellGSE12603 74018762 74019163 401 5827
hScc1 CdLSGSE12603 74018726 74019236 510 5846
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 73671351 73671962 611 0
CTCF JurkatGSE12889 73922025 73922193 168 0
CTCF G2GSE9613 73683021 73683268 247 0
CTCF G2GSE9613 73838748 73839100 352 0
CTCF G2GSE9613 73844209 73844541 332 0
CTCF G2GSE9613 73849657 73850066 409 0
CTCF G2GSE9613 73921957 73922397 440 0
CTCF G2GSE9613 73975880 73976088 208 0
CTCF G2GSE9613 73987852 73988192 340 0
ER E2-MCF7GSE14664 73617993 73618034 41 0
ER E2-MCF7GSE14664 73627712 73627757 45 0
ER E2-MCF7GSE14664 73628956 73629054 98 0
ER E2-MCF7GSE14664 73713124 73713161 37 0
ER E2-MCF7GSE14664 73715560 73715649 89 0
ER Fulvestrant-MCF7GSE14664 73627714 73627753 39 0
ER Fulvestrant-MCF7GSE14664 73949697 73949783 86 0
GABP HelaGSE8489 73985099 73985602 503 0
NRSF JurkatGSE13047 73908030 73908723 693 0
NRSF JurkatGSE13047 73993501 73994384 883 0
NRSF mAbJurkat 73906220 73907352 1132 0
NRSF mAbJurkat 73907825 73910359 2534 0
NRSF mAbJurkat 73992460 73994383 1923 0
NRSF-mono JurkatQuESTdata 73908158 73908695 537 0
NRSF-mono JurkatQuESTdata 73993747 73994377 630 0
NRSF-poly JurkatQuESTdata 73908234 73908753 519 0
NRSF-poly JurkatQuESTdata 73993793 73994365 572 0
Nanog hESGSE18292 73624033 73624337 304 0
Nanog hESGSE18292 73726119 73726328 209 0
Oct1 H2O2-HelaGSE14283 73657524 73657551 27 0
Oct1 H2O2-HelaGSE14283 73659651 73659688 37 0
Oct1 H2O2-HelaGSE14283 73666769 73666795 26 0
Oct1 H2O2-HelaGSE14283 73811031 73811086 55 0
Oct1 HelaGSE14283 73630615 73630650 35 0
Oct1 HelaGSE14283 73657520 73657553 33 0
Oct1 HelaGSE14283 73659651 73659680 29 0
Oct1 HelaGSE14283 73671695 73671722 27 0
Oct1 HelaGSE14283 73706925 73706951 26 0
Oct1 HelaGSE14283 73737183 73737211 28 0
Oct1 HelaGSE14283 73743211 73743247 36 0
Oct1 HelaGSE14283 73752767 73752797 30 0
Oct1 HelaGSE14283 73775266 73775314 48 0
Oct1 HelaGSE14283 73782468 73782507 39 0
Oct1 HelaGSE14283 73811032 73811077 45 0
Oct4 hESGSE17917 73849651 73850019 368 0
RARA MCF7GSE15244 73853614 73854278 664 0
RARG MCF7GSE15244 73847291 73847872 581 0
Stat6 IL-4-hr4GSE17850 73897933 73898529 596 0
TFAP2C MCF7GSE21234 73956856 73957424 568 0
hScc1 BcellGSE12603 73921957 73922397 440 0
hScc1 CdLSGSE12603 73921957 73922397 440 0
hScc1 G2GSE9613 73921957 73922464 507 0
p130 SenescentGSE19898 73705469 73705763 294 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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