AutismKB 2.0

Annotation Detail for TRIP11


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Basic Information Top
Gene Symbol:TRIP11 ( ACG1A,CEV14,GMAP-210,TRIP230 )
Gene Full Name: thyroid hormone receptor interactor 11
Band: 14q32.12
Quick LinksEntrez ID:9321; OMIM: 604505; Uniprot ID:TRIPB_HUMAN; ENSEMBL ID: ENSG00000100815; HGNC ID: 12305
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
464Phosphoserine.
486Phosphoserine.
1008Phosphoserine.
1842Phosphoserine.
1846Phosphothreonine.
1891Phosphoserine.
Location(AA) Modifications Resource
1891Phosphoserine.Swiss-Prot 53.0
1891PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
32N-linkedHMM predict
130Phosphoserine(IKK)HMM predict
133O-linkedHMM predict
140O-linkedHMM predict
141O-linkedHMM predict
170Phosphoserine(ATM)HMM predict
186Phosphoserine(CK1)HMM predict
224N-linkedHMM predict
226Phosphoserine(ATM)HMM predict
237Phosphoserine(CK1)HMM predict
259Phosphoserine(CK2)HMM predict
259Phosphoserine(CK1)HMM predict
261Phosphotyrosine(INSR)HMM predict
288Phosphotyrosine(Syk)HMM predict
395Phosphoserine(CK2)HMM predict
405Phosphoserine(PKG)HMM predict
432Phosphoserine(IKK)HMM predict
432Phosphoserine(CK1)HMM predict
435Phosphoserine(ATM)HMM predict
452Phosphotyrosine(Jak)HMM predict
452Phosphotyrosine(SRC)HMM predict
452Phosphotyrosine(Syk)HMM predict
464Phosphoserine(CAMK2)HMM predict
488Phosphoserine(CK2)HMM predict
593N-linkedHMM predict
595Phosphoserine(ATM)HMM predict
599N-linkedHMM predict
621Phosphoserine(CK1)HMM predict
797Phosphoserine(CK1)HMM predict
799Phosphoserine(CK1)HMM predict
825Phosphoserine(CK1)HMM predict
854Phosphoserine(IKK)HMM predict
899Phosphoserine(IKK)HMM predict
923N-linkedHMM predict
951N-linkedHMM predict
1006N-linkedHMM predict
1086Phosphotyrosine(Abl)HMM predict
1231O-linkedHMM predict
1259N-linkedHMM predict
1260N-linkedHMM predict
1261Phosphoserine(CK1)HMM predict
1277N-linkedHMM predict
1283N-linkedHMM predict
1313Phosphoserine(MAPK)HMM predict
1320O-linkedHMM predict
1335Phosphoserine(IKK)HMM predict
1339Phosphoserine(CK1)HMM predict
1342Phosphoserine(CK1)HMM predict
1376Phosphoserine(IKK)HMM predict
1391Phosphothreonine(CK2)HMM predict
1429N-linkedHMM predict
1432N-linkedHMM predict
1435N-linkedHMM predict
1479Phosphotyrosine(SRC)HMM predict
1522Phosphothreonine(CK2)HMM predict
1594Phosphoserine(CK1)HMM predict
1629N-linkedHMM predict
1662Phosphoserine(ATM)HMM predict
1773N-linkedHMM predict
1794Phosphothreonine(CDC2)HMM predict
1827Phosphoserine(CK1)HMM predict
1842Phosphoserine(IKK)HMM predict
1846Phosphothreonine(CDK)HMM predict
1846Phosphothreonine(CDC2)HMM predict
1846Phosphothreonine(MAPK)HMM predict
1854Phosphoserine(IKK)HMM predict
1857N-linkedHMM predict
1875O-linkedHMM predict
1875Phosphoserine(PKA)HMM predict
1891Phosphoserine(CDC2)HMM predict
1899Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004239
  • Location:chr14 91505613-91576138
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 91575517 91577031 1514 136
H3K4me3 colorectalcancer 91576782 91577246 464 876
H3ac HepG2E 91576523 91577003 480 625
PHF8 293TGSE20725 91575400 91576944 1544 34
PHF8 HeLaGSE20725 91575559 91576919 1360 101
PHF8 Hs68minusFBSGSE20725 91575381 91576918 1537 11
PHF8 Hs68plusFBSGSE20725 91575158 91577399 2241 140
PolII HeLaGSE12783 91575068 91577530 2462 161
RARA MCF7GSE15244 91576454 91577175 721 676
RARG MCF7GSE15244 91576418 91576750 332 446
Rb SenescentGSE19898 91575976 91576602 626 151
TAFII hESGSE17917 91576000 91576591 591 157
p130 shRbSenescentGSE19898 91575784 91576581 797 44
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 91500473 91500508 35 5123
Oct1 HelaGSE14283 91500473 91500509 36 5123
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 91532960 91533265 305 0
Fos K562GSE19551 91516344 91516685 341 0
H3K4me3 colorectalcancer 91574791 91576064 1273 0
H3ac HepG2E 91573983 91576127 2144 0
Oct1 HelaGSE14283 91512400 91512436 36 0
P300 T30-glioblastomaGSE21026 91575590 91576621 1031 0
RARA MCF7GSE15244 91575400 91576091 691 0
RARG MCF7GSE15244 91575501 91576064 563 0
TAF HelaGSE8489 91574969 91576064 1095 0
TAF k562GSE8489 91573983 91576454 2471 0
hScc1 BcellGSE12603 91532960 91533302 342 0
hScc1 CdLSGSE12603 91532960 91533338 378 0
p130 QuiescentGSE19898 91575309 91576365 1056 0
p130 SenescentGSE19898 91575394 91576873 1479 0
p130 shRbQuiescentGSE19898 91575443 91576559 1116 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
266 Unknown MicroArray miR-124 TRIP11 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000100815 G1-to-S transition n_a n_a "epithelium, lymphoblast, lymphocyte, muscle cell" "malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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