AutismKB 2.0

Annotation Detail for TPTE2


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Basic Information Top
Gene Symbol:TPTE2 ( MGC149231,TPIP )
Gene Full Name: transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Band: 13q12.11
Quick LinksEntrez ID:93492; OMIM: 606791; Uniprot ID:TPTE2_HUMAN; ENSEMBL ID: ENSG00000132958; HGNC ID: 17299
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
8N-linkedHMM predict
103Phosphotyrosine(INSR)HMM predict
213Phosphothreonine(PKA)HMM predict
329Phosphothreonine(PKA)HMM predict
350Phosphotyrosine(Jak)HMM predict
357N-linkedHMM predict
362N-linkedHMM predict
369Phosphothreonine(CDK)HMM predict
481N-linkedHMM predict
487N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_130785
  • Location:chr13 18895020-19008902
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18884445 18884821 376 10388
Oct1 HelaGSE14283 18882139 18882168 29 12867
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 18916448 18916665 217 0
CBP T30-glioblastomaGSE21026 18916320 18916636 316 0
CTCF JurkatGSE12889 18911319 18911456 137 0
CTCF G2GSE9613 18904018 18904279 261 0
GABP HelaGSE8489 18900930 18901630 700 0
GABP HelaGSE8489 18949526 18949935 409 0
GABP HelaGSE8489 18978741 18979419 678 0
Nanog ESGSE20650 18911220 18911476 256 0
Nanog ESGSE20650 18969249 18969494 245 0
Oct1 H2O2-HelaGSE14283 18918465 18918495 30 0
Oct1 H2O2-HelaGSE14283 18989730 18989769 39 0
Oct1 HelaGSE14283 18897973 18898043 70 0
Oct1 HelaGSE14283 18989730 18989771 41 0
P300 T30-glioblastomaGSE21026 18916449 18916637 188 0
RNAII Tamoxifen-MCF7GSE14664 18895554 18895593 39 0
TFAP2C MCF7GSE21234 18910843 18911552 709 0
TFAP2C MCF7GSE21234 18945232 18945599 367 0
TFAP2C MCF7GSE21234 18959701 18960314 613 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018