AutismKB 2.0

Annotation Detail for TBCK


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Basic Information Top
Gene Symbol:TBCK ( MGC16169,TBCKL )
Gene Full Name: TBC1 domain containing kinase
Band: 4q24
Quick LinksEntrez ID:93627; OMIM: NA; Uniprot ID:TBCK_HUMAN; ENSEMBL ID: ENSG00000145348; HGNC ID: 28261
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
890Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
89Phosphoserine(IKK)HMM predict
175O-linkedHMM predict
198S-palmitoylHMM predict
263O-linkedHMM predict
263Phosphothreonine(PKA)HMM predict
281O-linkedHMM predict
497Phosphothreonine(CDC2)HMM predict
520Phosphoserine(CK1)HMM predict
521Phosphoserine(ATM)HMM predict
521Phosphoserine(CDC2)HMM predict
567Phosphotyrosine(INSR)HMM predict
651N-linkedHMM predict
721O-linkedHMM predict
724Phosphoserine(CK1)HMM predict
732Phosphotyrosine(Jak)HMM predict
734O-linkedHMM predict
782Phosphothreonine(CDC2)HMM predict
782Phosphothreonine(CDK)HMM predict
784Phosphoserine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033115
  • Location:chr4 107186688-107456833
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 107456449 107457383 934 83
ETS1 JurkatGSE17954 107455965 107457761 1796 30
TAF HelaGSE8489 107455543 107458261 2718 69
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 107333926 107334152 226 0
CTCF G2GSE9613 107406765 107407127 362 0
ER E2-MCF7GSE14664 107263358 107263394 36 0
ER Fulvestrant-MCF7GSE14664 107234887 107234922 35 0
ER MCF7GSE19013 107203017 107203551 534 0
H3K4me3 colorectalcancer 107455957 107456826 869 0
H3ac HepG2E 107454342 107454615 273 0
H3ac HepG2E 107454866 107455197 331 0
Myc hESGSE17917 107349402 107349775 373 0
Nanog ESGSE20650 107261103 107261400 297 0
Nanog ESGSE20650 107363120 107363606 486 0
Oct1 H2O2-HelaGSE14283 107215227 107215259 32 0
Oct1 H2O2-HelaGSE14283 107234882 107234919 37 0
Oct1 H2O2-HelaGSE14283 107242446 107242480 34 0
Oct1 H2O2-HelaGSE14283 107361096 107361127 31 0
Oct1 H2O2-HelaGSE14283 107406812 107406858 46 0
Oct1 HelaGSE14283 107191470 107191506 36 0
Oct1 HelaGSE14283 107234880 107234928 48 0
Oct1 HelaGSE14283 107242442 107242486 44 0
Oct1 HelaGSE14283 107291611 107291697 86 0
Oct1 HelaGSE14283 107298407 107298449 42 0
Oct1 HelaGSE14283 107361089 107361137 48 0
Oct1 HelaGSE14283 107406811 107406859 48 0
Oct1 HelaGSE14283 107432050 107432085 35 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20046 mRNA SCYE1 chr4 107595278 107627176 47 mRNA MGC16169 chr4 107324843 107595399Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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