AutismKB 2.0

Annotation Detail for GRAP2


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Basic Information Top
Gene Symbol:GRAP2 ( GADS,GRAP-2,GRB2L,GRBLG,GRID,GRPL,GrbX,Grf40,Mona,P38 )
Gene Full Name: GRB2-related adaptor protein 2
Band: 22q13.1
Quick LinksEntrez ID:9402; OMIM: 604518; Uniprot ID:GRAP2_HUMAN; ENSEMBL ID: ENSG00000100351; HGNC ID: 4563
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
45Phosphotyrosine.
106N6-acetyllysine.
262Phosphothreonine.
Location(AA) Modifications Resource
45Phosphotyrosine.Swiss-Prot 53.0
45PhosphotyrosinePhospho.ELM 6.0
262Phosphothreonine.Swiss-Prot 53.0
262PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
18Phosphoserine(CK1)HMM predict
41Phosphoserine(CK1)HMM predict
45Phosphotyrosine(INSR)HMM predict
87Phosphoserine(IKK)HMM predict
187Phosphoserine(PKG)HMM predict
192Phosphothreonine(CDK)HMM predict
262Phosphothreonine(PKA)HMM predict
262PhosphothreonineHMM predict
305N-linkedHMM predict
312ArginineHMM predict
324Phosphotyrosine(Abl)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004810
  • Location:chr22 38627031-38697329
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 38623903 38624439 536 2861
hScc1 BcellGSE12603 38626400 38626681 281 491
hScc1 CdLSGSE12603 38626711 38627228 517 62
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 38708460 38708903 443 11352
CTCF G2GSE9613 38706578 38706791 213 9355
Fos K562GSE19551 38709883 38710285 402 12755
P300 T0-glioblastomaGSE21026 38708558 38708904 346 11402
hScc1 BcellGSE12603 38709186 38709761 575 12144
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 38658753 38659013 260 0
CTCF CD4GSE12889 38666782 38667014 232 0
CTCF CD4GSE12889 38685587 38685722 135 0
CTCF CD4SISSRdata 38658753 38659013 260 0
CTCF CD4SISSRdata 38666782 38667014 232 0
CTCF CD4SISSRdata 38685587 38685722 135 0
CTCF G2GSE9613 38659052 38659467 415 0
FOXA1 MCF7GSE15244 38691860 38692181 321 0
Gata1 K562GSE18868 38645882 38646693 811 0
Gata2 K562GSE18868 38645890 38646685 795 0
P300 T30-glioblastomaGSE21026 38686650 38688017 1367 0
TAF k562GSE8489 38674006 38675198 1192 0
TFAP2C MCF7GSE21234 38664414 38664920 506 0
hScc1 CdLSGSE12603 38666366 38666953 587 0
hScc1 CdLSGSE12603 38687381 38687814 433 0
p63 keratinocytesGSE17611 38654306 38655145 839 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018