AutismKB 2.0

Annotation Detail for MED21


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MED21 ( SRB7,SURB7 )
Gene Full Name: mediator complex subunit 21
Band: 12p12
Quick LinksEntrez ID:9412; OMIM: 603800; Uniprot ID:MED21_HUMAN; ENSEMBL ID: ENSG00000152944; HGNC ID: 11473
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
49N-linkedHMM predict
54Phosphotyrosine(Syk)HMM predict
78Phosphoserine(CK1)HMM predict
138O-linkedHMM predict
138Phosphoserine(ATM)HMM predict
138Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004264
  • Location:chr12 27066749-27073948
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27066408 27066631 223 230
Fos K562GSE19551 27066401 27067032 631 33
H3ac HepG2E 27065839 27066021 182 820
hScc1 BcellGSE12603 27066408 27066783 375 154
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 27083750 27083961 211 9907
CTCF CD4SISSRdata 27083750 27083961 211 9907
CTCF JurkatGSE12889 27083747 27083927 180 9889
CTCF G2GSE9613 27084137 27084391 254 10316
Fos K562GSE19551 27093291 27093788 497 19591
Jun K562GSE19551 27093289 27093608 319 19500
Myc K562GSE19551 27093391 27093604 213 19549
hScc1 G2GSE9613 27084137 27084464 327 10352
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 27066408 27067249 841 0
H3ac HepG2E 27066408 27067389 981 0
P300 T30-glioblastomaGSE21026 27066421 27067381 960 0
TAF HelaGSE8489 27066408 27067389 981 0
TAF k562GSE8489 27066408 27067389 981 0
TAFII hESGSE17917 27066496 27067109 613 0
hScc1 CdLSGSE12603 27067053 27067389 336 0
p130 QuiescentGSE19898 27066597 27067205 608 0
p130 SenescentGSE19898 27066557 27067119 562 0
p130 shRbQuiescentGSE19898 27066570 27067302 732 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018