AutismKB 2.0

Annotation Detail for DDX23


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Basic Information Top
Gene Symbol:DDX23 ( MGC8416,PRPF28,U5-100K,U5-100KD,prp28 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Band: 12q13.12
Quick LinksEntrez ID:9416; OMIM: 612172; Uniprot ID:DDX23_HUMAN; ENSEMBL ID: ENSG00000174243; HGNC ID: 17347
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
14Phosphoserine.
25Phosphothreonine.
107Phosphoserine.
109Phosphoserine.
419Q motif.
552DEAD box.
Location(AA) Modifications Resource
14Phosphoserine.Swiss-Prot 53.0
14PhosphoserinePhospho.ELM 6.0
25Phosphothreonine.Swiss-Prot 53.0
25PhosphothreoninePhospho.ELM 6.0
67PhosphoserinePhospho.ELM 6.0
107Phosphoserine.Swiss-Prot 53.0
107PhosphoserinePhospho.ELM 6.0
109Phosphoserine.Swiss-Prot 53.0
109PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
14PhosphoserineHMM predict
14Phosphoserine(CDC2)HMM predict
23Phosphoserine(PKG)HMM predict
25Phosphothreonine(PKA)HMM predict
25Phosphothreonine(MAPK)HMM predict
25Phosphothreonine(CDK)HMM predict
25Phosphothreonine(CDC2)HMM predict
39PhosphoserineHMM predict
39Phosphoserine(CDC2)HMM predict
65Phosphoserine(PKB)HMM predict
65Phosphoserine(CK1)HMM predict
65Phosphoserine(IKK)HMM predict
106Phosphoserine(PKG)HMM predict
107Phosphoserine(PKA)HMM predict
107Phosphoserine(PKG)HMM predict
109Phosphoserine(CDC2)HMM predict
124Phosphoserine(CK1)HMM predict
244Phosphoserine(CK1)HMM predict
264Phosphothreonine(PKA)HMM predict
286SulfotyrosineHMM predict
320SulfotyrosineHMM predict
329Phosphothreonine(PKC)HMM predict
396Phosphoserine(CDC2)HMM predict
411Phosphotyrosine(Syk)HMM predict
537Phosphotyrosine(Jak)HMM predict
573O-linkedHMM predict
599Phosphotyrosine(EGFR)HMM predict
602Phosphothreonine(PKC)HMM predict
789Phosphoserine(IKK)HMM predict
810Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004818
  • Location:chr12 47509806-47532223
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47533382 47533723 341 1329
CTCF CD4SISSRdata 47533382 47533723 341 1329
CTCF G2GSE9613 47532929 47533526 597 1004
ETS1 JurkatGSE17954 47531656 47533123 1467 166
FOXA1 MCF7GSE15244 47532123 47533526 1403 601
H3K4me2 HCT116GSE10453 47532576 47533501 925 815
H3ac HepG2E 47531567 47533282 1715 201
P300 T0-glioblastomaGSE21026 47531731 47532853 1122 69
P300 T30-glioblastomaGSE21026 47531655 47532815 1160 12
PHF8 293TGSE20725 47531854 47532746 892 77
RARA MCF7GSE15244 47532273 47533526 1253 676
RARG MCF7GSE15244 47532350 47533526 1176 715
Rb GrowingGSE19898 47531983 47532526 543 31
Rb shRbSenescenceGSE19898 47532401 47532517 116 236
TAF HelaGSE8489 47532929 47533526 597 1004
TAF k562GSE8489 47532576 47533526 950 828
hScc1 BcellGSE12603 47533075 47533526 451 1077
hScc1 CdLSGSE12603 47533075 47533526 451 1077
hScc1 G2GSE9613 47532892 47533526 634 986
p130 QuiescentGSE19898 47532134 47532601 467 144
p130 SenescentGSE19898 47532088 47532637 549 139
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47510301 47510643 342 0
CTCF G2GSE9613 47511411 47511590 179 0
CTCF G2GSE9613 47512410 47512970 560 0
CTCF G2GSE9613 47531787 47532350 563 0
ER Fulvestrant-MCF7GSE14664 47531162 47531196 34 0
H3K4me2 HCT116GSE10453 47530227 47531086 859 0
H3K4me3 colorectalcancer 47530406 47531214 808 0
H3K4me3 colorectalcancer 47531567 47531971 404 0
H3ac HepG2E 47528377 47528604 227 0
H3ac HepG2E 47529810 47531214 1404 0
PHF8 HeLaGSE20725 47531449 47532705 1256 0
Rb QuiescentGSE19898 47531546 47532606 1060 0
Rb SenescentGSE19898 47531538 47532701 1163 0
TAF HelaGSE8489 47514262 47514474 212 0
TAF HelaGSE8489 47529846 47531214 1368 0
TAF HelaGSE8489 47531567 47532008 441 0
TAF k562GSE8489 47531567 47532008 441 0
p130 QuiescentGSE19898 47531602 47532087 485 0
p130 shRbQuiescentGSE19898 47531590 47532579 989 0
p130 shRbSenescentGSE19898 47531740 47532614 874 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018