AutismKB 2.0

Annotation Detail for TNFSF8


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Basic Information Top
Gene Symbol:TNFSF8 ( CD153,CD30L,CD30LG,MGC138144 )
Gene Full Name: tumor necrosis factor (ligand) superfamily, member 8
Band: 9q32-q33.1
Quick LinksEntrez ID:944; OMIM: 603875; Uniprot ID:TNFL8_HUMAN; ENSEMBL ID: ENSG00000106952; HGNC ID: 11938
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
81N-linked (GlcNAc...) (Potential).
109N-linked (GlcNAc...) (Potential).
153N-linked (GlcNAc...) (Potential).
189N-linked (GlcNAc...) (Potential).
201N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
81N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
109N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
153N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
189N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
201N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
67Phosphoserine(IKK)HMM predict
67PhosphoserineHMM predict
71Phosphoserine(CDC2)HMM predict
109N-linkedHMM predict
201N-linkedHMM predict
207N-linkedHMM predict
213SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001244
  • Location:chr9 116704944-116732590
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 116686773 116687526 753 17795
CBP T30-glioblastomaGSE21026 116696246 116697586 1340 8029
Nanog ESGSE20650 116690757 116691141 384 13996
P300 T0-glioblastomaGSE21026 116686755 116687218 463 17958
P300 T30-glioblastomaGSE21026 116686820 116687537 717 17766
P300 T30-glioblastomaGSE21026 116696095 116697671 1576 8062
TFAP2C MCF7GSE21234 116692111 116692431 320 12674
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 116709048 116709410 362 0
CTCF CD4SISSRdata 116709048 116709410 362 0
FOXA1 MCF7GSE15244 116710044 116711375 1331 0
FoxA1 MCF7MACSdata 116710023 116710696 673 0
Nanog hESGSE18292 116727861 116728094 233 0
Oct1 H2O2-HelaGSE14283 116712016 116712043 27 0
Oct1 HelaGSE14283 116712014 116712044 30 0
P300 T30-glioblastomaGSE21026 116709971 116711224 1253 0
RARA MCF7GSE15244 116710044 116712009 1965 0
Rb shRbQuiescentGSE19898 116719892 116720130 238 0
TFAP2C MCF7GSE21234 116709974 116710776 802 0
hScc1 BcellGSE12603 116708874 116709696 822 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018