Annotation Detail for ARHGEF6
Basic Information Top
| Gene Symbol: | ARHGEF6 ( COOL2,Cool-2,KIAA0006,MRX46,PIXA,alpha-PIX,alphaPIX ) |
|---|---|
| Gene Full Name: | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| Band: | Xq26.3 |
| Quick Links | Entrez ID:9459; OMIM: 300267; Uniprot ID:ARHG6_HUMAN; ENSEMBL ID: ENSG00000129675; HGNC ID: 685 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 122 | Phosphoserine (By similarity). | |
| 126 | Phosphoserine. | |
| 144 | Phosphoserine. | |
| 150 | Phosphoserine. | |
| 188 | Phosphotyrosine. | |
| 225 | Phosphoserine. | |
| 488 | Phosphoserine. | |
| 640 | Phosphoserine. | |
| 650 | Phosphothreonine (By similarity). | |
| 684 | Phosphoserine. | |
| 751 | N6-acetyllysine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 122 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 225 | Phosphoserine. | Swiss-Prot 53.0 |
| 225 | Phosphoserine | Phospho.ELM 6.0 |
| 488 | Phosphoserine. | Swiss-Prot 53.0 |
| 488 | Phosphoserine | Phospho.ELM 6.0 |
| 640 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 650 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 |
| 684 | Phosphoserine. | Swiss-Prot 53.0 |
| 684 | Phosphoserine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 19 | Phosphoserine(CDC2) | HMM predict |
| 110 | Phosphothreonine(CK2) | HMM predict |
| 124 | Phosphoserine(PKB) | HMM predict |
| 124 | O-linked | HMM predict |
| 126 | Phosphoserine(IKK) | HMM predict |
| 129 | N-linked | HMM predict |
| 131 | O-linked | HMM predict |
| 134 | N-linked | HMM predict |
| 142 | O-linked | HMM predict |
| 158 | N-linked | HMM predict |
| 225 | Phosphoserine(MAPK) | HMM predict |
| 225 | Phosphoserine(CDC2) | HMM predict |
| 329 | Phosphoserine(Jak) | HMM predict |
| 349 | Phosphoserine | HMM predict |
| 363 | Phosphoserine(CDC2) | HMM predict |
| 484 | Phosphoserine(CDK) | HMM predict |
| 552 | Phosphoserine(IKK) | HMM predict |
| 555 | Phosphoserine(IKK) | HMM predict |
| 555 | Phosphoserine(CK1) | HMM predict |
| 560 | O-linked | HMM predict |
| 562 | Phosphoserine(CK2) | HMM predict |
| 569 | O-linked | HMM predict |
| 569 | Phosphoserine(IKK) | HMM predict |
| 571 | Phosphoserine(CK1) | HMM predict |
| 571 | O-linked | HMM predict |
| 622 | Phosphoserine(IKK) | HMM predict |
| 622 | Phosphoserine(CDC2) | HMM predict |
| 635 | Phosphothreonine(PKC) | HMM predict |
| 640 | Phosphoserine(PKC) | HMM predict |
| 640 | Phosphoserine(PKG) | HMM predict |
| 640 | Phosphoserine(CK1) | HMM predict |
| 650 | Phosphothreonine(PKA) | HMM predict |
| 680 | Phosphothreonine(PKC) | HMM predict |
| 684 | Phosphoserine(IKK) | HMM predict |
| 684 | Phosphoserine(PKG) | HMM predict |
| 770 | Phosphoserine(CK1) | HMM predict |
- RefSeq ID: NM_004840
- Location:chrX 135575376-135691168
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| FOXA1 | MCF7 | GSE15244 | 135692792 | 135693693 | 901 | 2074 |
| FoxA1 | MCF7 | MACSdata | 135693002 | 135693353 | 351 | 2009 |
| NRSF | mAb | Jurkat | 135690876 | 135692279 | 1403 | 409 |
| Nanog | hES | GSE18292 | 135704070 | 135704331 | 261 | 13032 |
| Oct1 | Hela | GSE14283 | 135700435 | 135700489 | 54 | 9294 |
| Oct1 | Hela | GSE14283 | 135700527 | 135700567 | 40 | 9379 |
| RARA | MCF7 | GSE15244 | 135692750 | 135694119 | 1369 | 2266 |
| RARG | MCF7 | GSE15244 | 135692750 | 135694119 | 1369 | 2266 |
| TFAP2C | MCF7 | GSE21234 | 135692874 | 135693534 | 660 | 2036 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 135598407 | 135599926 | 1519 | 0 |
| CTCF | CD4 | GSE12889 | 135604712 | 135605034 | 322 | 0 |
| CTCF | CD4 | GSE12889 | 135618231 | 135618529 | 298 | 0 |
| CTCF | CD4 | SISSRdata | 135604712 | 135605034 | 322 | 0 |
| CTCF | CD4 | SISSRdata | 135618231 | 135618529 | 298 | 0 |
| CTCF | G2 | GSE9613 | 135604436 | 135604931 | 495 | 0 |
| CTCF | G2 | GSE9613 | 135676812 | 135677889 | 1077 | 0 |
| ER | E2-MCF7 | GSE14664 | 135635756 | 135635792 | 36 | 0 |
| NFkBII | GM12878 | GSE19485 | 135619779 | 135620936 | 1157 | 0 |
| Nanog | ES | GSE20650 | 135669891 | 135670392 | 501 | 0 |
| Oct1 | Hela | GSE14283 | 135585191 | 135585269 | 78 | 0 |
| Oct1 | Hela | GSE14283 | 135595035 | 135595090 | 55 | 0 |
| Oct1 | Hela | GSE14283 | 135612337 | 135612367 | 30 | 0 |
| Oct4 | ES | GSE20650 | 135669942 | 135670308 | 366 | 0 |
| RARA | MCF7 | GSE15244 | 135678065 | 135678688 | 623 | 0 |
| TAF | k562 | GSE8489 | 135678029 | 135678651 | 622 | 0 |
| TFAP2C | MCF7 | GSE21234 | 135577073 | 135578106 | 1033 | 0 |
| TFAP2C | MCF7 | GSE21234 | 135678302 | 135678747 | 445 | 0 |
| hScc1 | Bcell | GSE12603 | 135644962 | 135645182 | 220 | 0 |
| hScc1 | Bcell | GSE12603 | 135676689 | 135677959 | 1270 | 0 |
| hScc1 | CdLS | GSE12603 | 135604362 | 135604966 | 604 | 0 |
| hScc1 | G2 | GSE9613 | 135582393 | 135582792 | 399 | 0 |
| hScc1 | G2 | GSE9613 | 135604290 | 135604894 | 604 | 0 |
| hScc1 | G2 | GSE9613 | 135640637 | 135640904 | 267 | 0 |
| hScc1 | G2 | GSE9613 | 135676780 | 135677815 | 1035 | 0 |
Validated miRNA targets