AutismKB 2.0

Annotation Detail for ADAMTS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ADAMTS1 ( C3-C5,KIAA1346,METH1 )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 1
Band: 21q21.3
Quick LinksEntrez ID:9510; OMIM: 605174; Uniprot ID:ATS1_HUMAN; ENSEMBL ID: ENSG00000154734; HGNC ID: 217
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
203Cysteine switch (By similarity).
547N-linked (GlcNAc...) (Potential).
720N-linked (GlcNAc...) (Potential).
764N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
547N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
720N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
764N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
113Phosphothreonine(CDK)HMM predict
113Phosphothreonine(MAPK)HMM predict
208Phosphothreonine(PKC)HMM predict
213Phosphothreonine(CK2)HMM predict
230Phosphoserine(IKK)HMM predict
259Phosphotyrosine(Abl)HMM predict
398Phosphothreonine(PKC)HMM predict
440Phosphoserine(ATM)HMM predict
443C-linkedHMM predict
444Phosphoserine(IKK)HMM predict
504Phosphoserine(IKK)HMM predict
508O-linkedHMM predict
547N-linkedHMM predict
562C-linkedHMM predict
565C-linkedHMM predict
568C-linkedHMM predict
684Phosphoserine(MAPK)HMM predict
687O-linkedHMM predict
688O-linkedHMM predict
689Phosphoserine(IKK)HMM predict
720N-linkedHMM predict
732Phosphothreonine(PKC)HMM predict
732O-linkedHMM predict
764N-linkedHMM predict
815Phosphoserine(CDC2)HMM predict
838Phosphotyrosine(Jak)HMM predict
917C-linkedHMM predict
924S-palmitoylHMM predict
953LysineHMM predict
960PhenylalanineHMM predict
961PhenylalanineHMM predict
962PhenylalanineHMM predict
963PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006988
  • Location:chr21 27130478-27139598
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27144428 27144897 469 5064
H3K27me3 colorectalcancer 27140924 27142054 1130 1891
TFAP2C MCF7GSE21234 27152513 27153104 591 13210
hScc1 CdLSGSE12603 27144494 27144897 403 5097
hScc1 G2GSE9613 27144256 27145282 1026 5171
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 27113112 27113488 376 17179
Nanog hESGSE18292 27113070 27113517 447 17185
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 27133617 27135553 1936 0
CTCF G2GSE9613 27138412 27139503 1091 0
hScc1 BcellGSE12603 27138340 27138951 611 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125b hsa-mir-125b-1 11 18056640
hsa-miR-125b hsa-mir-125b-2 21 18056640
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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