Annotation Detail for LITAF

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Basic Information Top

Gene Symbol:	LITAF ( FLJ38636,MGC116698,MGC116700,MGC116701,MGC125274,MGC125275,MGC125276,PIG7,SIMPLE,TP53I7 )
Gene Full Name:	lipopolysaccharide-induced TNF factor
Band:	16p13.13
Quick Links	Entrez ID:9516; OMIM: 603795; Uniprot ID:LITAF_HUMAN; ENSEMBL ID: ENSG00000189067; HGNC ID: 16841
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
23	WW-binding.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	11588090	11588490	400	561
Fos	K562	GSE19551	11598449	11599030	581	11010
KLF4	hES	GSE17917	11587934	11588230	296	353
Oct1	Hela	GSE14283	11604972	11604998	26	17256
Oct4	hES	GSE17917	11597705	11598447	742	10347
P300	T30-glioblastoma	GSE21026	11598210	11599464	1254	11108
PHF8	HeLa	GSE20725	11587826	11589137	1311	752
hScc1	Bcell	GSE12603	11588027	11588660	633	614
hScc1	CdLS	GSE12603	11587967	11588525	558	517

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	11533508	11533786	278	15710
CTCF	CD4	SISSRdata	11533508	11533786	278	15710
CTCF	Hela	GSE12889	11533611	11533841	230	15631
CTCF	Jurkat	GSE12889	11533445	11533832	387	15718
CTCF	G2	GSE9613	11536135	11536545	410	13017
CTCF	G2	GSE9613	11545230	11545719	489	3882
CTCF	G2	GSE9613	11546760	11546943	183	2505
FOXA1	MCF7	GSE15244	11536135	11536979	844	12800
NRSF	pAb	Jurkat	11545382	11545719	337	3806
Oct1	H2O2-Hela	GSE14283	11535568	11535604	36	13771
Oct1	Hela	GSE14283	11530918	11530954	36	18421
Oct1	Hela	GSE14283	11535571	11535605	34	13769
Oct4	ES	GSE20650	11545046	11545344	298	4162
RARA	MCF7	GSE15244	11536135	11536979	844	12800

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	11557679	11557889	210
CTCF	G2	GSE9613	11573473	11573871	398
FOXA1	MCF7	GSE15244	11585177	11586026	849
FoxA1	MCF7	MACSdata	11585305	11585670	365
H3K4me3	colorectal	cancer	11586620	11587967	1347
H3ac	HepG2	E	11583597	11586161	2564
H3ac	HepG2	E	11586620	11587483	863
NFkBII	GM12878	GSE19485	11576353	11577404	1051
Nanog	hES	GSE18292	11583513	11584438	925
TAF	Hela	GSE8489	11586620	11587286	666
TFAP2C	MCF7	GSE21234	11577922	11578592	670
USF2	HepG2	E	11576710	11577166	456
p63	keratinocytes	GSE17611	11563565	11564300	735

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-122	hsa-mir-122	18	20956972
hsa-miR-122*	hsa-mir-122	18	20956972
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-200a	hsa-mir-200a	1	20956972
hsa-miR-200a*	hsa-mir-200a	1	20956972
hsa-miR-200b	hsa-mir-200b	1	20956972
hsa-miR-200b*	hsa-mir-200b	1	20956972
hsa-miR-21	hsa-mir-21	17	20956972
hsa-miR-21*	hsa-mir-21	17	20956972
hsa-miR-23a	hsa-mir-23a	19	15066185
hsa-miR-23a*	hsa-mir-23a	19	15066185
hsa-miR-27a	hsa-mir-27a	19	20956972
hsa-miR-27a*	hsa-mir-27a	19	20956972
hsa-miR-27b	hsa-mir-27b	9	20956972
hsa-miR-27b*	hsa-mir-27b	9	20956972
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193
hsa-miR-429	hsa-mir-429	1	20956972
hsa-miR-451	hsa-mir-451	17	20956972

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
366	Unknown	MicroArray	miR-124	LITAF	n_a	15685193
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000189067		G1-to-S transition	n_a	n_a	"epithelium, lymphocyte, leukocyte, macrophage"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018