Annotation Detail for GDF15
Basic Information Top
| Gene Symbol: | GDF15 ( GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB ) |
|---|---|
| Gene Full Name: | growth differentiation factor 15 |
| Band: | 19p13.11 |
| Quick Links | Entrez ID:9518; OMIM: 605312; Uniprot ID:GDF15_HUMAN; ENSEMBL ID: ENSG00000130513; HGNC ID: 30142 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 70 | N-linked (GlcNAc...) (Potential). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 70 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 10 | N-linked | HMM predict |
| 31 | Phosphoserine(PKG) | HMM predict |
| 39 | Phosphoserine(IKK) | HMM predict |
| 70 | N-linked | HMM predict |
| 106 | Phosphoserine(PKA) | HMM predict |
| 128 | Phosphoserine(CDC2) | HMM predict |
| 146 | Phosphoserine(CAMK2) | HMM predict |
| 146 | Phosphoserine(PKG) | HMM predict |
| 146 | Phosphoserine(PKA) | HMM predict |
| 160 | Phosphoserine(ATM) | HMM predict |
| 164 | Phosphoserine(ATM) | HMM predict |
| 215 | Phosphothreonine(PKC) | HMM predict |
| 219 | Phosphoserine(PKG) | HMM predict |
| 231 | Phosphoserine(CDC2) | HMM predict |
| 244 | S-palmitoyl | HMM predict |
| 296 | Phosphothreonine(PKC) | HMM predict |
- RefSeq ID: NM_004864
- Location:chr19 18357984-18360985
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 18354639 | 18354837 | 198 | 3247 |
| CTCF | G2 | GSE9613 | 18357543 | 18358319 | 776 | 54 |
| ER | MCF7 | GSE19013 | 18351811 | 18352846 | 1035 | 5656 |
| FOXA1 | MCF7 | GSE15244 | 18351925 | 18352366 | 441 | 5839 |
| FoxA1 | MCF7 | MACSdata | 18351931 | 18352363 | 432 | 5838 |
| H3ac | HepG2 | E | 18353870 | 18354280 | 410 | 3910 |
| H3ac | HepG2 | E | 18354639 | 18355140 | 501 | 3095 |
| HIF1 | Hypo | HepG2 | 18351925 | 18352366 | 441 | 5839 |
| RARA | MCF7 | GSE15244 | 18351925 | 18352366 | 441 | 5839 |
| TAF | Hela | GSE8489 | 18351925 | 18352103 | 178 | 5971 |
| TAF | k562 | GSE8489 | 18351925 | 18352211 | 286 | 5917 |
| p130 | shRbSenescent | GSE19898 | 18357834 | 18358074 | 240 | 31 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 18360243 | 18360520 | 277 | 0 |
| CTCF | CD4 | SISSRdata | 18360243 | 18360520 | 277 | 0 |
| CTCF | G2 | GSE9613 | 18359954 | 18360693 | 739 | 0 |
| FOXA1 | MCF7 | GSE15244 | 18357543 | 18358577 | 1034 | 0 |
| H3ac | HepG2 | E | 18357975 | 18359044 | 1069 | 0 |
| Myc | hES | GSE17917 | 18360265 | 18360707 | 442 | 0 |
| VDR | GM10861-Unstim | GSE22484 | 18359945 | 18360992 | 1047 | 0 |
| hScc1 | Bcell | GSE12603 | 18357864 | 18358319 | 455 | 0 |
| hScc1 | Bcell | GSE12603 | 18360119 | 18360759 | 640 | 0 |
| hScc1 | CdLS | GSE12603 | 18359954 | 18360622 | 668 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-103 | hsa-mir-103-2 | 20 | 19011694 |
| hsa-miR-103 | hsa-mir-103-1 | 5 | 19011694 |
| hsa-miR-103 | hsa-mir-103-2 | 20 | 19011694 |
| hsa-miR-103 | hsa-mir-103-1 | 5 | 19011694 |
| hsa-miR-22 | hsa-mir-22 | 17 | 19011694 |
| hsa-miR-22 | hsa-mir-22 | 17 | 19011694 |
| hsa-miR-22* | hsa-mir-22 | 17 | 19011694 |
| hsa-miR-22* | hsa-mir-22 | 17 | 19011694 |
| No data |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12902 | mRNA | GDF15 | chr19 | 18357984 | 18360986 | 337 | EST | chr19 | 18358017 | 18360337 | Sense/Antisense (SA) pairs | |