Annotation Detail for ENTPD3

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Basic Information Top

Gene Symbol:	ENTPD3 ( CD39L3,FLJ93839,HB6,NTPDase-3 )
Gene Full Name:	ectonucleoside triphosphate diphosphohydrolase 3
Band:	3p22.1
Quick Links	Entrez ID:956; OMIM: 603161; Uniprot ID:ENTP3_HUMAN; ENSEMBL ID: ENSG00000168032; HGNC ID: 3365
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:7 results
Experimental PTM Sites from dbPTM:7 results
Predicted PTM Sites by profile HMM from dbPTM:11 results

Location(AA)	Modification
81	N-linked (GlcNAc...) (Potential).
149	N-linked (GlcNAc...) (Potential).
238	N-linked (GlcNAc...) (Potential).
381	N-linked (GlcNAc...) (Potential).
392	N-linked (GlcNAc...) (Potential).
402	N-linked (GlcNAc...) (Potential).
454	N-linked (GlcNAc...) (Potential).

Location(AA)	Modifications	Resource
81	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
149	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
238	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
381	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
392	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
402	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
454	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Location(AA)	Modification	Resource
81	N-linked	HMM predict
82	N-linked	HMM predict
149	N-linked	HMM predict
154	N-linked	HMM predict
185	Phosphotyrosine(SRC)	HMM predict
279	Phosphoserine(CDC2)	HMM predict
381	N-linked	HMM predict
392	N-linked	HMM predict
397	N-linked	HMM predict
402	N-linked	HMM predict
518	Phosphoserine(PKA)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001248
Location:chr3 40403696-40445112
strand:+

Upstream the gene:3 results
Downstream the gene:4 results
Inside the gene:15 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	40403222	40403853	631	159
Fos	K562	GSE19551	40396448	40396865	417	7040
Myc	K562	GSE19551	40388628	40388909	281	14928

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
NRSF	Jurkat	GSE13047	40454348	40454736	388	9430
NRSF	mAb	Jurkat	40451752	40452473	721	7000
NRSF-mono	Jurkat	QuESTdata	40454483	40454735	252	9497
NRSF-poly	Jurkat	QuESTdata	40454359	40454795	436	9465

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	40409863	40409895	32	0
ER	MCF7	GSE19013	40434377	40435117	740	0
FOXA1	MCF7	GSE15244	40412480	40413430	950	0
FOXA1	MCF7	GSE15244	40434097	40435063	966	0
Fos	K562	GSE19551	40434370	40435115	745	0
FoxA1	MCF7	MACSdata	40412933	40413299	366	0
FoxA1	MCF7	MACSdata	40434624	40435082	458	0
NRSF-poly	Jurkat	QuESTdata	40419419	40419717	298	0
Oct1	Hela	GSE14283	40409863	40409896	33	0
Oct1	Hela	GSE14283	40420185	40420251	66	0
RARA	MCF7	GSE15244	40412480	40413430	950	0
RARA	MCF7	GSE15244	40434097	40435063	966	0
RARG	MCF7	GSE15244	40412513	40413430	917	0
RARG	MCF7	GSE15244	40434097	40435063	966	0
p63	keratinocytes	GSE17611	40434321	40435065	744	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
17958	mRNA	ENTPD3	chr3	40403696	40445113	128	mRNA	FLJ36665	chr3	40407445	40469800	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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