AutismKB 2.0

Annotation Detail for BCAR1


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Basic Information Top
Gene Symbol:BCAR1 ( CAS,CAS1,CASS1,CRKAS,FLJ12176,FLJ45059,P130Cas )
Gene Full Name: breast cancer anti-estrogen resistance 1
Band: 16q23.1
Quick LinksEntrez ID:9564; OMIM: 602941; Uniprot ID:BCAR1_HUMAN; ENSEMBL ID: ENSG00000050820; HGNC ID: 971
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
128Phosphotyrosine.
134Phosphoserine.
139Phosphoserine.
222Phosphotyrosine.
224Phosphotyrosine.
234Phosphotyrosine.
249Phosphotyrosine.
267Phosphotyrosine.
269Phosphothreonine.
287Phosphotyrosine.
292Phosphoserine.
327Phosphotyrosine.
362Phosphotyrosine.
387Phosphotyrosine.
410Phosphotyrosine.
639Phosphoserine.
643SH3-binding (Potential).
Location(AA) Modifications Resource
128Phosphotyrosine.Swiss-Prot 53.0
128Phosphotyrosine (FGFR1)Phospho.ELM 6.0
139Phosphoserine.Swiss-Prot 53.0
165PhosphotyrosinePhospho.ELM 6.0
222Phosphotyrosine.Swiss-Prot 53.0
224Phosphotyrosine.Swiss-Prot 53.0
234Phosphotyrosine.Swiss-Prot 53.0
249Phosphotyrosine (FGFR1)Phospho.ELM 6.0
249Phosphotyrosine.Swiss-Prot 53.0
306Phosphotyrosine (FGFR1)Phospho.ELM 6.0
327Phosphotyrosine (FGFR1)Phospho.ELM 6.0
327Phosphotyrosine.Swiss-Prot 53.0
362Phosphotyrosine (By similarity).Swiss-Prot 53.0
387PhosphotyrosinePhospho.ELM 6.0
387Phosphotyrosine.Swiss-Prot 53.0
410Phosphotyrosine (By similarity).Swiss-Prot 53.0
410Phosphotyrosine (FGFR1)Phospho.ELM 6.0
639Phosphoserine.Swiss-Prot 53.0
639PhosphoserinePhospho.ELM 6.0
653Phosphotyrosine (FAK;Src)Phospho.ELM 6.0
664Phosphotyrosine (FAK)Phospho.ELM 6.0
Location(AA) Modification Resource
76O-linkedHMM predict
97Phosphoserine(ATM)HMM predict
107Phosphotyrosine(Syk)HMM predict
115Phosphotyrosine(Syk)HMM predict
134Phosphoserine(CDC2)HMM predict
139Phosphoserine(CDC2)HMM predict
139Phosphoserine(IKK)HMM predict
145Phosphothreonine(PKC)HMM predict
159O-linkedHMM predict
179Phosphotyrosine(Syk)HMM predict
192Phosphotyrosine(Syk)HMM predict
202Phosphoserine(IKK)HMM predict
234PhosphotyrosineHMM predict
234Phosphotyrosine(Syk)HMM predict
234SulfotyrosineHMM predict
249Phosphotyrosine(Syk)HMM predict
249PhosphotyrosineHMM predict
267Phosphotyrosine(Syk)HMM predict
267Phosphotyrosine(Abl)HMM predict
287Phosphotyrosine(Syk)HMM predict
306Phosphotyrosine(Syk)HMM predict
327Phosphotyrosine(Syk)HMM predict
327Phosphotyrosine(SRC)HMM predict
327PhosphotyrosineHMM predict
344Phosphothreonine(MAPK)HMM predict
355Phosphoserine(CDC2)HMM predict
362Phosphotyrosine(Syk)HMM predict
362Phosphotyrosine(SRC)HMM predict
362PhosphotyrosineHMM predict
362Phosphotyrosine(Abl)HMM predict
372Phosphotyrosine(Abl)HMM predict
372Phosphotyrosine(Syk)HMM predict
387Phosphotyrosine(Abl)HMM predict
410Phosphotyrosine(Abl)HMM predict
410PhosphotyrosineHMM predict
410Phosphotyrosine(Syk)HMM predict
430Phosphoserine(CDC2)HMM predict
435O-linkedHMM predict
438Phosphoserine(PKA)HMM predict
438Phosphoserine(ATM)HMM predict
438Phosphoserine(IKK)HMM predict
442Phosphoserine(IKK)HMM predict
443Phosphoserine(CK1)HMM predict
473Phosphothreonine(PKC)HMM predict
489Phosphoserine(IKK)HMM predict
611Phosphothreonine(PKA)HMM predict
624N-linkedHMM predict
626O-linkedHMM predict
645Phosphoserine(IKK)HMM predict
648Phosphoserine(IKK)HMM predict
648Phosphoserine(CAMK2)HMM predict
653PhosphotyrosineHMM predict
666SulfotyrosineHMM predict
666PhosphotyrosineHMM predict
721N-linkedHMM predict
754N-linkedHMM predict
760N-linkedHMM predict
839Phosphoserine(CDK)HMM predict
839Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014567
  • Location:chr16 73820429-73843003
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 73843943 73844812 869 1374
CTCF G2GSE9613 73854214 73854791 577 11499
ER E2-MCF7GSE14664 73855874 73855946 72 12907
FOXA1 MCF7GSE15244 73845593 73846355 762 2971
FoxA1 MCF7MACSdata 73845859 73846162 303 3007
NRSF pAbJurkat 73853232 73855054 1822 11140
PHF8 293TGSE20725 73856879 73858056 1177 14464
Rb GrowingGSE19898 73843357 73843519 162 435
Rb GrowingGSE19898 73861318 73861463 145 18387
Rb SenescentGSE19898 73843035 73843410 375 219
Rb shRbQuiescentGSE19898 73855825 73856040 215 12929
TFAP2C MCF7GSE21234 73843117 73843897 780 504
TFAP2C MCF7GSE21234 73845559 73846569 1010 3061
TFAP2C MCF7GSE21234 73847352 73848259 907 4802
TFAP2C MCF7GSE21234 73859056 73859870 814 16460
hScc1 BcellGSE12603 73847418 73847566 148 4489
hScc1 BcellGSE12603 73857433 73857716 283 14571
p130 QuiescentGSE19898 73855770 73856252 482 13008
p130 QuiescentGSE19898 73857431 73858129 698 14777
p130 SenescentGSE19898 73855983 73856453 470 13215
p130 SenescentGSE19898 73856830 73857118 288 13971
p130 SenescentGSE19898 73857443 73857631 188 14534
p130 shRbQuiescentGSE19898 73843171 73843698 527 431
p130 shRbQuiescentGSE19898 73845847 73846320 473 3080
p130 shRbQuiescentGSE19898 73857413 73857952 539 14679
p130 shRbSenescentGSE19898 73843095 73843597 502 343
p130 shRbSenescentGSE19898 73855845 73856283 438 13061
p130 shRbSenescentGSE19898 73857422 73857713 291 14564
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 73836497 73837303 806 0
CBP T30-glioblastomaGSE21026 73835315 73837629 2314 0
CTCF CD4GSE12889 73825234 73825575 341 0
CTCF CD4SISSRdata 73825234 73825575 341 0
CTCF HelaGSE12889 73825253 73825542 289 0
CTCF JurkatGSE12889 73825272 73825564 292 0
CTCF G2GSE9613 73825202 73825779 577 0
CTCF G2GSE9613 73829691 73830757 1066 0
CTCF G2GSE9613 73832082 73832423 341 0
CTCF G2GSE9613 73835117 73836089 972 0
CTCF G2GSE9613 73836551 73837240 689 0
CTCF G2GSE9613 73838434 73838731 297 0
CTCF G2GSE9613 73842068 73843291 1223 0
H3ac HepG2E 73837677 73838594 917 0
H3ac HepG2E 73840834 73842140 1306 0
Myc K562GSE19551 73825211 73825823 612 0
NRSF pAbJurkat 73836517 73836912 395 0
P300 T30-glioblastomaGSE21026 73835294 73839450 4156 0
TFAP2C MCF7GSE21234 73835581 73836157 576 0
TFAP2C MCF7GSE21234 73836518 73837305 787 0
VDR GM10861-stimGSE22484 73824961 73825926 965 0
hScc1 BcellGSE12603 73825165 73825919 754 0
hScc1 BcellGSE12603 73826609 73827277 668 0
hScc1 BcellGSE12603 73841664 73843325 1661 0
hScc1 CdLSGSE12603 73825165 73825744 579 0
hScc1 CdLSGSE12603 73842663 73843325 662 0
p130 shRbQuiescentGSE19898 73825376 73825764 388 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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