AutismKB 2.0

Annotation Detail for CDC42BPB


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Basic Information Top
Gene Symbol:CDC42BPB ( DKFZp686H1431,FLJ37601,FLJ44730,KIAA1124,MRCKB )
Gene Full Name: CDC42 binding protein kinase beta (DMPK-like)
Band: 14q32.32
Quick LinksEntrez ID:9578; OMIM: NA; Uniprot ID:MRCKB_HUMAN; ENSEMBL ID: ENSG00000198752; HGNC ID: 1738
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
221Phosphoserine; by autocatalysis (By
233Phosphoserine; by autocatalysis (By
239Phosphothreonine; by autocatalysis (By
362Phosphoserine.
363Phosphoserine.
676Phosphothreonine.
914Phosphoserine.
954Phosphotyrosine (By similarity).
1196Phosphothreonine.
1686Phosphoserine.
1690Phosphoserine.
1693Phosphoserine.
Location(AA) Modifications Resource
221Phosphoserine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
233Phosphoserine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
239Phosphothreonine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
914Phosphoserine.Swiss-Prot 53.0
914PhosphoserinePhospho.ELM 6.0
954Phosphotyrosine (By similarity).Swiss-Prot 53.0
1690PhosphoserinePhospho.ELM 6.0
1690Phosphoserine.Swiss-Prot 53.0
1693Phosphoserine.Swiss-Prot 53.0
1693PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
21N-linkedHMM predict
26Phosphoserine(CK1)HMM predict
51Phosphotyrosine(Jak)HMM predict
150Phosphotyrosine(SRC)HMM predict
150Phosphotyrosine(INSR)HMM predict
150Phosphotyrosine(Syk)HMM predict
242Phosphotyrosine(Jak)HMM predict
242Phosphotyrosine(INSR)HMM predict
242Phosphotyrosine(EGFR)HMM predict
310Phosphoserine(CK2)HMM predict
363Phosphoserine(CDK)HMM predict
365Phosphoserine(CK2)HMM predict
365Phosphoserine(CK1)HMM predict
410Phosphoserine(CK1)HMM predict
414Phosphoserine(CK1)HMM predict
425Phosphothreonine(CK2)HMM predict
479Phosphoserine(PKC)HMM predict
479Phosphoserine(PKG)HMM predict
524PhosphoserineHMM predict
524Phosphoserine(CK1)HMM predict
558Phosphoserine(PKG)HMM predict
722Phosphoserine(CK1)HMM predict
724PhosphoserineHMM predict
757Phosphothreonine(PKC)HMM predict
762Phosphotyrosine(Jak)HMM predict
852Phosphoserine(CK1)HMM predict
868Phosphoserine(PKG)HMM predict
904N-linkedHMM predict
969Phosphoserine(CK2)HMM predict
970Phosphoserine(IKK)HMM predict
984O-linkedHMM predict
988O-linkedHMM predict
1006O-linkedHMM predict
1035Phosphoserine(IKK)HMM predict
1063S-palmitoylHMM predict
1108Phosphothreonine(PKC)HMM predict
1155Phosphoserine(CK1)HMM predict
1297S-palmitoylHMM predict
1585N-linkedHMM predict
1588N-linkedHMM predict
1590N-linkedHMM predict
1615Phosphoserine(ATM)HMM predict
1638Phosphotyrosine(Jak)HMM predict
1659Phosphoserine(CK1)HMM predict
1673Phosphoserine(CK1)HMM predict
1674O-linkedHMM predict
1677Phosphoserine(IKK)HMM predict
1678Phosphothreonine(MAPK)HMM predict
1678Phosphothreonine(CDK)HMM predict
1681N-linkedHMM predict
1684N-linkedHMM predict
1686Phosphoserine(ATM)HMM predict
1690O-linkedHMM predict
1690Phosphoserine(CDK)HMM predict
1690Phosphoserine(ATM)HMM predict
1690Phosphoserine(CDC2)HMM predict
1690Phosphoserine(IKK)HMM predict
1693Phosphoserine(CDC2)HMM predict
1697Phosphoserine(ATM)HMM predict
1700ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006035
  • Location:chr14 102468468-102593494
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102593903 102594078 175 496
CTCF G2GSE9613 102605934 102606221 287 12583
CTCF G2GSE9613 102607693 102608151 458 14428
CTCF G2GSE9613 102611684 102611931 247 18313
GABP HelaGSE8489 102598559 102598850 291 5210
H3ac HepG2E 102598559 102598850 291 5210
Myc hESGSE17917 102593894 102594126 232 516
Oct1 H2O2-HelaGSE14283 102605516 102605552 36 12040
Oct1 HelaGSE14283 102596388 102596417 29 2908
Oct1 HelaGSE14283 102605502 102605552 50 12033
Oct1 HelaGSE14283 102607774 102607807 33 14296
PHF8 HeLaGSE20725 102592740 102594454 1714 103
RARA MCF7GSE15244 102598559 102598850 291 5210
Rb QuiescentGSE19898 102594207 102594439 232 829
TFAP2C MCF7GSE21234 102607446 102608337 891 14397
TFAP2C MCF7GSE21234 102608868 102611493 2625 16686
hScc1 BcellGSE12603 102611411 102611931 520 18177
hScc1 CdLSGSE12603 102611064 102611931 867 18003
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 102508591 102509033 442 0
CBP T30-glioblastomaGSE21026 102508586 102509224 638 0
CTCF CD4GSE12889 102485294 102485460 166 0
CTCF CD4SISSRdata 102485294 102485460 166 0
CTCF G2GSE9613 102474063 102474273 210 0
CTCF G2GSE9613 102479722 102479891 169 0
CTCF G2GSE9613 102480719 102481236 517 0
CTCF G2GSE9613 102486124 102486572 448 0
CTCF G2GSE9613 102505007 102505571 564 0
CTCF G2GSE9613 102522944 102523421 477 0
CTCF G2GSE9613 102537435 102537688 253 0
CTCF G2GSE9613 102539203 102539455 252 0
CTCF G2GSE9613 102542130 102542282 152 0
CTCF G2GSE9613 102558057 102558351 294 0
CTCF G2GSE9613 102577535 102577754 219 0
CTCF G2GSE9613 102593049 102593440 391 0
Fos K562GSE19551 102547078 102547458 380 0
H3K4me3 colorectalcancer 102593207 102593440 233 0
H3ac HepG2E 102591544 102592321 777 0
Myc K562GSE19551 102477602 102478104 502 0
NRSF JurkatGSE13047 102581425 102581847 422 0
NRSF JurkatSISSRdata 102581480 102581839 359 0
NRSF-mono JurkatQuESTdata 102581424 102581908 484 0
NRSF-poly JurkatQuESTdata 102581434 102581830 396 0
Oct1 HelaGSE14283 102501177 102501212 35 0
P300 T0-glioblastomaGSE21026 102508741 102509072 331 0
PHF8 Hs68plusFBSGSE20725 102592799 102593806 1007 0
RARG MCF7GSE15244 102523089 102523457 368 0
RARG MCF7GSE15244 102529543 102530145 602 0
TFAP2C MCF7GSE21234 102469870 102470253 383 0
TFAP2C MCF7GSE21234 102476166 102476649 483 0
TFAP2C MCF7GSE21234 102546975 102547649 674 0
TFAP2C MCF7GSE21234 102567639 102568521 882 0
hScc1 BcellGSE12603 102480574 102481349 775 0
hScc1 BcellGSE12603 102485196 102485584 388 0
hScc1 BcellGSE12603 102486158 102486545 387 0
hScc1 BcellGSE12603 102493686 102493888 202 0
hScc1 BcellGSE12603 102537104 102537649 545 0
hScc1 BcellGSE12603 102565991 102566148 157 0
hScc1 BcellGSE12603 102577535 102578117 582 0
hScc1 BcellGSE12603 102593207 102593440 233 0
p63 keratinocytesGSE17611 102522972 102523809 837 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8406 mRNA chr14 102464734 102469686 760 mRNA CDC42BPB chr14 102468469 102593552Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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