AutismKB 2.0

Annotation Detail for PDIA4


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Basic Information Top
Gene Symbol:PDIA4 ( ERP70,ERP72,ERp-72 )
Gene Full Name: protein disulfide isomerase family A, member 4
Band: 7q36.1
Quick LinksEntrez ID:9601; OMIM: NA; Uniprot ID:PDIA4_HUMAN; ENSEMBL ID: ENSG00000155660; HGNC ID: 30167
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
366N6-acetyllysine.
645Prevents secretion from ER.
Location(AA) Modifications Resource
Location(AA) Modification Resource
31Phosphoserine(CK1)HMM predict
91S-palmitoylHMM predict
126Phosphoserine(IKK)HMM predict
139Phosphothreonine(PKC)HMM predict
156Phosphothreonine(PKC)HMM predict
173Phosphothreonine(MAPK)HMM predict
206S-palmitoylHMM predict
227Phosphoserine(CDC2)HMM predict
320SulfotyrosineHMM predict
320Phosphotyrosine(SRC)HMM predict
323Phosphotyrosine(Syk)HMM predict
410Phosphothreonine(PKC)HMM predict
448SulfotyrosineHMM predict
458Phosphotyrosine(INSR)HMM predict
458Phosphotyrosine(Syk)HMM predict
458SulfotyrosineHMM predict
555S-palmitoylHMM predict
595Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004911
  • Location:chr7 148331088-148356674
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 148356189 148357220 1031 30
FOXA1 MCF7GSE15244 148356910 148357404 494 483
Fos K562GSE19551 148355995 148357388 1393 17
Fos K562GSE19551 148369421 148369802 381 12937
FoxA1 MCF7MACSdata 148372046 148372275 229 15486
LIN9 G0GSE7516 148356479 148357127 648 129
LIN9 SGSE7516 148356408 148356954 546 7
PHF8 HeLaGSE20725 148355938 148357552 1614 71
PHF8 Hs68plusFBSGSE20725 148356015 148357505 1490 86
Rb QuiescentGSE19898 148356910 148357079 169 320
Rb SenescentGSE19898 148356661 148357127 466 220
Rb SenescentGSE19898 148357143 148357387 244 591
hScc1 BcellGSE12603 148370726 148370990 264 14184
p130 QuiescentGSE19898 148356494 148356926 432 36
p130 SenescentGSE19898 148356423 148357271 848 173
p130 shRbQuiescentGSE19898 148356622 148356916 294 95
p130 shRbSenescentGSE19898 148356501 148357228 727 190
p130 SGSE7516 148356507 148357090 583 124
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 148315534 148315804 270 15420
CTCF G2GSE9613 148330708 148330876 168 297
Pol3 GM12878GSE19551 148314672 148315641 969 15932
Pol3 K562GSE19551 148311487 148312192 705 19249
TAF k562GSE8489 148313969 148314396 427 16906
USF1 HepG2E 148313969 148314285 316 16962
USF2 HepG2E 148313969 148314186 217 17011
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 148333769 148334076 307 0
CTCF CD4SISSRdata 148333769 148334076 307 0
CTCF G2GSE9613 148332898 148336017 3119 0
CTCF G2GSE9613 148338540 148338793 253 0
CTCF G2GSE9613 148340380 148340947 567 0
CTCF G2GSE9613 148342289 148342543 254 0
CTCF G2GSE9613 148350557 148350770 213 0
CTCF G2GSE9613 148355985 148357090 1105 0
FOXA1 MCF7GSE15244 148332621 148333649 1028 0
H3K4me2 HCT116GSE10453 148354848 148355985 1137 0
H3K4me3 colorectalcancer 148354848 148356057 1209 0
H3ac HepG2E 148354848 148356091 1243 0
PHF8 293TGSE20725 148355664 148357267 1603 0
TAF k562GSE8489 148355069 148355985 916 0
hScc1 BcellGSE12603 148333509 148334043 534 0
hScc1 BcellGSE12603 148355883 148356479 596 0
hScc1 CdLSGSE12603 148333575 148334163 588 0
hScc1 G2GSE9613 148333724 148334893 1169 0
hScc1 G2GSE9613 148355985 148357023 1038 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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