AutismKB 2.0

Annotation Detail for TRAF4


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Basic Information Top
Gene Symbol:TRAF4 ( CART1,MLN62,RNF83 )
Gene Full Name: TNF receptor-associated factor 4
Band: 17q11.2
Quick LinksEntrez ID:9618; OMIM: 602464; Uniprot ID:TRAF4_HUMAN; ENSEMBL ID: ENSG00000076604; HGNC ID: 12034
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
426Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
18S-palmitoylHMM predict
21S-palmitoylHMM predict
32Phosphoserine(PKC)HMM predict
153Phosphotyrosine(INSR)HMM predict
153Phosphotyrosine(EGFR)HMM predict
155PhosphoserineHMM predict
192Phosphothreonine(PKA)HMM predict
212Phosphotyrosine(Jak)HMM predict
257S-palmitoylHMM predict
303Phosphoserine(CK1)HMM predict
355N-linkedHMM predict
387Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004295
  • Location:chr17 24095172-24101222
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata1 K562GSE18868 24094230 24094880 650 618
Gata2 K562GSE18868 24094245 24094976 731 562
Oct1 HelaGSE14283 24094762 24094794 32 395
PHF8 293TGSE20725 24094242 24095743 1501 180
PHF8 HeLaGSE20725 24094146 24095877 1731 161
hScc1 BcellGSE12603 24094548 24095376 828 211
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 24101173 24101628 455 178
CTCF CD4SISSRdata 24101173 24101628 455 178
CTCF G2GSE9613 24101252 24101696 444 252
hScc1 BcellGSE12603 24101215 24101671 456 221
hScc1 CdLSGSE12603 24101179 24101869 690 302
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 24097557 24098270 713 0
H3ac HepG2E 24095731 24096469 738 0
NFkBII GM12892GSE19485 24093937 24097493 3556 0
Pol2 GM12878GSE19551 24094153 24100806 6653 0
RARA MCF7GSE15244 24097196 24098552 1356 0
RARG MCF7GSE15244 24095941 24096233 292 0
RARG MCF7GSE15244 24097389 24098093 704 0
TFAP2C MCF7GSE21234 24096062 24098863 2801 0
hScc1 BcellGSE12603 24096446 24096616 170 0
hScc1 BcellGSE12603 24099559 24100121 562 0
p130 shRbSenescentGSE19898 24096123 24096566 443 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018