AutismKB 2.0

Annotation Detail for TTLL4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TTLL4 ( KIAA0173 )
Gene Full Name: tubulin tyrosine ligase-like family, member 4
Band: 2q35
Quick LinksEntrez ID:9654; OMIM: NA; Uniprot ID:TTLL4_HUMAN; ENSEMBL ID: ENSG00000135912; HGNC ID: 28976
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
9Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
25O-linkedHMM predict
27Phosphothreonine(PKC)HMM predict
27O-linkedHMM predict
31O-linkedHMM predict
31Phosphothreonine(MAPK)HMM predict
31Phosphothreonine(CDK)HMM predict
31PhosphothreonineHMM predict
31O-linkedHMM predict
86O-linkedHMM predict
89O-linkedHMM predict
113N-linkedHMM predict
122Phosphoserine(PKB)HMM predict
139Phosphoserine(CDC2)HMM predict
139PhosphoserineHMM predict
156Phosphoserine(IKK)HMM predict
169O-linkedHMM predict
182Phosphotyrosine(Jak)HMM predict
191N-linkedHMM predict
207Phosphoserine(CDC2)HMM predict
207Phosphoserine(MAPK)HMM predict
211Phosphoserine(CDC2)HMM predict
226N-linkedHMM predict
243Phosphoserine(CDC2)HMM predict
295O-linkedHMM predict
296Phosphoserine(CK1)HMM predict
299Phosphoserine(CAMK2)HMM predict
299Phosphoserine(IKK)HMM predict
324Phosphoserine(CK1)HMM predict
325Phosphoserine(CK1)HMM predict
327Phosphoserine(ATM)HMM predict
365N-linkedHMM predict
371N-linkedHMM predict
470Phosphoserine(PKA)HMM predict
491Phosphoserine(CK2)HMM predict
491Phosphoserine(ATM)HMM predict
511Phosphothreonine(CK2)HMM predict
535Phosphoserine(IKK)HMM predict
539Phosphoserine(IKK)HMM predict
539Phosphoserine(CK1)HMM predict
544Phosphoserine(CDC2)HMM predict
544Phosphoserine(IKK)HMM predict
649Phosphoserine(PKC)HMM predict
947Phosphoserine(CK1)HMM predict
950Phosphoserine(CK2)HMM predict
950Phosphoserine(IKK)HMM predict
951Phosphoserine(IKK)HMM predict
951O-linkedHMM predict
954Phosphoserine(CK1)HMM predict
957O-linkedHMM predict
957O-linkedHMM predict
958Phosphoserine(IKK)HMM predict
958O-linkedHMM predict
958Phosphoserine(CK1)HMM predict
958O-linkedHMM predict
962Phosphoserine(ATM)HMM predict
962Phosphoserine(CDC2)HMM predict
962Phosphoserine(MAPK)HMM predict
962Phosphoserine(CDK)HMM predict
986Phosphothreonine(PKC)HMM predict
995Phosphotyrosine(Syk)HMM predict
1018Phosphoserine(CK1)HMM predict
1071S-palmitoylHMM predict
1107Phosphoserine(CK1)HMM predict
1109Phosphoserine(CK2)HMM predict
1112Phosphoserine(CK1)HMM predict
1132Phosphothreonine(CDC2)HMM predict
1150Phosphoserine(CDC2)HMM predict
1155Phosphoserine(IKK)HMM predict
1159Phosphoserine(CK1)HMM predict
1163Phosphoserine(CK1)HMM predict
1163Phosphoserine(IKK)HMM predict
1165O-linkedHMM predict
1179O-linkedHMM predict
1189Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014640
  • Location:chr2 219283886-219327651
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 219283172 219284504 1332 49
Rb shRbQuiescentGSE19898 219283656 219284039 383 39
USF1 HepG2E 219283587 219283809 222 189
p130 QuiescentGSE19898 219283684 219283959 275 65
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 219332745 219333017 272 5230
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 219283677 219284105 428 0
CTCF CD4GSE12889 219300915 219301078 163 0
CTCF CD4SISSRdata 219283677 219284105 428 0
CTCF CD4SISSRdata 219300915 219301078 163 0
CTCF G2GSE9613 219283587 219284236 649 0
Fos K562GSE19551 219290225 219290632 407 0
Fos K562GSE19551 219304476 219305103 627 0
Gata2 K562GSE18868 219304446 219304991 545 0
H3K4me3 colorectalcancer 219284515 219284884 369 0
H3ac HepG2E 219284419 219285209 790 0
Myc K562GSE19551 219304613 219304970 357 0
Myc K562GSE19551 219318043 219318648 605 0
NFkBII GM12892GSE19485 219306486 219307524 1038 0
Nanog ESGSE20650 219293553 219293997 444 0
P300 T30-glioblastomaGSE21026 219304164 219305228 1064 0
PHF8 293TGSE20725 219283644 219284727 1083 0
Rb QuiescentGSE19898 219284070 219284304 234 0
Rb SenescentGSE19898 219283491 219284331 840 0
hScc1 BcellGSE12603 219283587 219284236 649 0
hScc1 CdLSGSE12603 219283587 219284383 796 0
hScc1 G2GSE9613 219283587 219284272 685 0
p130 QuiescentGSE19898 219283984 219284181 197 0
p130 QuiescentGSE19898 219284233 219284403 170 0
p130 SenescentGSE19898 219283575 219284617 1042 0
p130 shRbQuiescentGSE19898 219283708 219284707 999 0
p130 shRbSenescentGSE19898 219283690 219284547 857 0
p130 shRbSenescentGSE19898 219318597 219319032 435 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved