AutismKB 2.0

Annotation Detail for KIAA0430


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Basic Information Top
Gene Symbol:KIAA0430 ( LKAP )
Gene Full Name: KIAA0430
Band: 16p13.11
Quick LinksEntrez ID:9665; OMIM: NA; Uniprot ID:LKAP_HUMAN; ENSEMBL ID: ENSG00000166783; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
582Phosphothreonine.
698Phosphotyrosine (By similarity).
914Phosphoserine.
1090Phosphoserine.
1092Phosphoserine (By similarity).
Location(AA) Modifications Resource
347PhosphothreoninePhospho.ELM 6.0
582Phosphothreonine.Swiss-Prot 53.0
679PhosphoserinePhospho.ELM 6.0
914Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
1AcetylmethionineHMM predict
8N-linkedHMM predict
35Phosphoserine(CK1)HMM predict
40Phosphothreonine(PKC)HMM predict
44Phosphoserine(CDK)HMM predict
44Phosphoserine(ATM)HMM predict
44Phosphoserine(CDC2)HMM predict
50Phosphotyrosine(INSR)HMM predict
114MethylarginineHMM predict
122O-linkedHMM predict
158Phosphoserine(CK1)HMM predict
161N-linkedHMM predict
166N-linkedHMM predict
167N-linkedHMM predict
183N-linkedHMM predict
192S-palmitoylHMM predict
193S-palmitoylHMM predict
241Phosphoserine(ATM)HMM predict
281Phosphoserine(PKG)HMM predict
336Phosphoserine(CDC2)HMM predict
360N-linkedHMM predict
365O-linkedHMM predict
417N-linkedHMM predict
422N-linkedHMM predict
459Phosphoserine(CK1)HMM predict
582Phosphothreonine(CDC2)HMM predict
603Phosphoserine(CDC2)HMM predict
619Phosphoserine(CK2)HMM predict
624O-linkedHMM predict
628Phosphothreonine(MAPK)HMM predict
633Phosphoserine(IKK)HMM predict
633O-linkedHMM predict
637Phosphoserine(IKK)HMM predict
680N-linkedHMM predict
682O-linkedHMM predict
682O-linkedHMM predict
687Phosphothreonine(CDK)HMM predict
687O-linkedHMM predict
687Phosphothreonine(MAPK)HMM predict
711Phosphoserine(CK1)HMM predict
713Phosphothreonine(PKC)HMM predict
715Phosphoserine(IKK)HMM predict
715Phosphoserine(CDC2)HMM predict
754Phosphoserine(IKK)HMM predict
759Phosphoserine(IKK)HMM predict
775N-linkedHMM predict
826Phosphoserine(ATM)HMM predict
874O-linkedHMM predict
876Phosphoserine(CK1)HMM predict
884Phosphoserine(CK1)HMM predict
950Phosphoserine(ATM)HMM predict
959N-linkedHMM predict
970Phosphotyrosine(INSR)HMM predict
970Phosphotyrosine(SRC)HMM predict
1012Phosphoserine(IKK)HMM predict
1092Phosphoserine(CDC2)HMM predict
1092Phosphoserine(IKK)HMM predict
1168Phosphothreonine(PKC)HMM predict
1179Phosphothreonine(PKA)HMM predict
1188Phosphoserine(ATM)HMM predict
1348Phosphoserine(ATM)HMM predict
1413Phosphoserine(CK1)HMM predict
1446Phosphothreonine(MAPK)HMM predict
1565Phosphoserine(CK1)HMM predict
1566Phosphoserine(CK1)HMM predict
1566Phosphoserine(IKK)HMM predict
1566Phosphoserine(PKA)HMM predict
1570Phosphoserine(CDC2)HMM predict
1570Phosphoserine(ATM)HMM predict
1594Phosphoserine(CAMK2)HMM predict
1603Phosphoserine(ATM)HMM predict
1634Phosphoserine(CDC2)HMM predict
1683O-linkedHMM predict
1684O-linkedHMM predict
1688Phosphoserine(IKK)HMM predict
1702O-linkedHMM predict
1702Phosphoserine(CK1)HMM predict
1706Phosphoserine(CK1)HMM predict
1717Phosphoserine(CDC2)HMM predict
1732N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014647
  • Location:chr16 15595745-15644509
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 15644657 15645237 580 438
H3ac HepG2E 15644657 15646244 1587 941
LIN9 SGSE7516 15644657 15645264 607 451
NFkBII GM12878GSE19485 15643254 15646301 3047 268
NFkBII GM12892GSE19485 15643052 15646349 3297 191
NFkBII GM15510GSE19485 15643382 15645706 2324 35
PHF8 293TGSE20725 15643783 15645310 1527 37
PHF8 HeLaGSE20725 15643741 15645316 1575 19
Rb QuiescentGSE19898 15644423 15644670 247 37
USF1 HepG2E 15644657 15646035 1378 837
USF2 HepG2E 15644657 15645127 470 383
p130 shRbSenescentGSE19898 15644130 15644990 860 51
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 15602703 15603055 352 0
CTCF G2GSE9613 15643923 15644345 422 0
ETS1 JurkatGSE17954 15643499 15645380 1881 0
FOXA1 MCF7GSE15244 15630248 15631313 1065 0
H3K4me3 colorectalcancer 15643610 15644100 490 0
H3ac HepG2E 15630113 15631453 1340 0
H3ac HepG2E 15642477 15644193 1716 0
NRSF JurkatGSE13047 15602519 15603084 565 0
NRSF JurkatSISSRdata 15602653 15602893 240 0
NRSF mAbJurkat 15601762 15603612 1850 0
NRSF mAbJurkat 15604023 15604512 489 0
NRSF-mono JurkatQuESTdata 15602518 15603066 548 0
NRSF-poly JurkatQuESTdata 15602412 15603084 672 0
Oct1 H2O2-HelaGSE14283 15620880 15620907 27 0
Oct1 HelaGSE14283 15625589 15625625 36 0
P300 T30-glioblastomaGSE21026 15609151 15610342 1191 0
hScc1 CdLSGSE12603 15643989 15644345 356 0
p130 SenescentGSE19898 15643760 15645067 1307 0
p130 shRbSenescentGSE19898 15600069 15600450 381 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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