AutismKB 2.0

Annotation Detail for UBE3C


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Basic Information Top
Gene Symbol:UBE3C ( KIAA0010,KIAA10 )
Gene Full Name: ubiquitin protein ligase E3C
Band: 7q36.3
Quick LinksEntrez ID:9690; OMIM: NA; Uniprot ID:UBE3C_HUMAN; ENSEMBL ID: ENSG00000009335; HGNC ID: 16803
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
82Phosphoserine(ATM)HMM predict
93N-linkedHMM predict
152S-palmitoylHMM predict
176Phosphoserine(CK1)HMM predict
181Phosphotyrosine(Syk)HMM predict
181Phosphotyrosine(SRC)HMM predict
207Phosphotyrosine(Jak)HMM predict
208Phosphotyrosine(EGFR)HMM predict
208Phosphotyrosine(Jak)HMM predict
355Phosphoserine(MAPK)HMM predict
355Phosphoserine(CDC2)HMM predict
360Phosphoserine(IKK)HMM predict
366Phosphoserine(CK2)HMM predict
366Phosphoserine(CK1)HMM predict
368Phosphoserine(CK2)HMM predict
368Phosphoserine(IKK)HMM predict
372Phosphoserine(CK2)HMM predict
372Phosphoserine(CK1)HMM predict
379Phosphoserine(CK2)HMM predict
380PhosphoserineHMM predict
489Phosphoserine(IKK)HMM predict
578O-linkedHMM predict
676Phosphoserine(ATM)HMM predict
724N-linkedHMM predict
730N-linkedHMM predict
733SulfotyrosineHMM predict
737Phosphotyrosine(INSR)HMM predict
737Phosphotyrosine(Syk)HMM predict
801Phosphotyrosine(INSR)HMM predict
867Phosphotyrosine(Syk)HMM predict
886N-linkedHMM predict
891N-linkedHMM predict
892N-linkedHMM predict
982Phosphotyrosine(INSR)HMM predict
1004Phosphothreonine(CK2)HMM predict
1061Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014671
  • Location:chr7 156624424-156754822
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 156610977 156611694 717 13089
CTCF G2GSE9613 156619822 156620184 362 4422
PHF8 HeLaGSE20725 156623454 156625175 1721 110
Rb SenescentGSE19898 156623828 156624124 296 449
TFAP2C MCF7GSE21234 156618109 156618599 490 6071
hScc1 BcellGSE12603 156623777 156624548 771 262
p130 QuiescentGSE19898 156610245 156610425 180 14090
p130 QuiescentGSE19898 156623787 156624094 307 484
p130 SenescentGSE19898 156623785 156624062 277 501
p130 shRbSenescentGSE19898 156623607 156624193 586 525
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 156759085 156759364 279 4402
CTCF CD4SISSRdata 156759085 156759364 279 4402
CTCF HelaGSE12889 156758941 156759434 493 4365
CTCF JurkatGSE12889 156759046 156759363 317 4382
CTCF G2GSE9613 156758956 156759309 353 4310
CTCF G2GSE9613 156765049 156765819 770 10612
CTCF G2GSE9613 156766119 156766346 227 11410
CTCF G2GSE9613 156767261 156767384 123 12500
CTCF G2GSE9613 156774620 156774994 374 19985
FOXA1 MCF7GSE15244 156757559 156758054 495 2984
P300 T30-glioblastomaGSE21026 156756816 156758074 1258 2623
TFAP2C MCF7GSE21234 156762349 156763092 743 7898
TFAP2C MCF7GSE21234 156766813 156767430 617 12299
hScc1 BcellGSE12603 156758821 156759165 344 4171
hScc1 BcellGSE12603 156762760 156763098 338 8107
hScc1 BcellGSE12603 156769230 156769416 186 14501
hScc1 G2GSE9613 156764713 156765417 704 10243
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 156714431 156714604 173 0
CTCF CD4GSE12889 156736085 156736413 328 0
CTCF CD4SISSRdata 156714431 156714604 173 0
CTCF CD4SISSRdata 156736085 156736413 328 0
CTCF G2GSE9613 156623952 156625079 1127 0
CTCF G2GSE9613 156714250 156714722 472 0
CTCF G2GSE9613 156749598 156750003 405 0
ER MCF7GSE19013 156740632 156741399 767 0
ER MCF7GSE10800 156740864 156741403 539 0
FOXA1 MCF7GSE15244 156636648 156638338 1690 0
FOXA1 MCF7GSE15244 156740864 156741116 252 0
FoxA1 MCF7MACSdata 156740495 156740861 366 0
FoxA1 MCF7MACSdata 156740874 156741086 212 0
Myc K562GSE19551 156736038 156736446 408 0
NRSF mAbJurkat 156674983 156675213 230 0
NRSF pAbJurkat 156749367 156750003 636 0
Nanog hESGSE18292 156674882 156675112 230 0
Oct4 hESGSE17917 156723683 156724048 365 0
P300 T30-glioblastomaGSE21026 156685704 156686144 440 0
PHF8 Hs68plusFBSGSE20725 156623451 156625494 2043 0
RARA MCF7GSE15244 156740864 156741257 393 0
TFAP2C MCF7GSE21234 156714185 156714779 594 0
hScc1 BcellGSE12603 156714250 156714722 472 0
hScc1 BcellGSE12603 156736081 156736447 366 0
hScc1 BcellGSE12603 156749559 156750003 444 0
hScc1 CdLSGSE12603 156714293 156714722 429 0
hScc1 CdLSGSE12603 156736081 156736551 470 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018