AutismKB 2.0

Annotation Detail for PUM1


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Basic Information Top
Gene Symbol:PUM1 ( HSPUM,KIAA0099,PUMH,PUMH1,PUML1 )
Gene Full Name: pumilio homolog 1 (Drosophila)
Band: 1p35.2
Quick LinksEntrez ID:9698; OMIM: 607204; Uniprot ID:PUM1_HUMAN; ENSEMBL ID: ENSG00000134644; HGNC ID: 14957
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Phosphoserine.
75Phosphoserine.
124Phosphoserine (By similarity).
209Phosphoserine.
709Phosphoserine.
714Phosphoserine.
806Phosphoserine.
Location(AA) Modifications Resource
209Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
19Phosphoserine(ATM)HMM predict
44Phosphoserine(ATM)HMM predict
44O-linkedHMM predict
44O-linkedHMM predict
44Phosphoserine(IKK)HMM predict
62O-linkedHMM predict
63O-linkedHMM predict
104N-linkedHMM predict
105N-linkedHMM predict
112Phosphothreonine(PKC)HMM predict
159Phosphoserine(CK1)HMM predict
179Phosphothreonine(PKC)HMM predict
183Phosphoserine(IKK)HMM predict
183Phosphoserine(CAMK2)HMM predict
185Phosphoserine(ATM)HMM predict
209Phosphoserine(MAPK)HMM predict
209Phosphoserine(CDC2)HMM predict
229Phosphoserine(CDC2)HMM predict
247PhosphoserineHMM predict
247Phosphoserine(CK2)HMM predict
247Phosphoserine(CK2)HMM predict
342Phosphoserine(ATM)HMM predict
344Phosphoserine(IKK)HMM predict
438O-linkedHMM predict
461Phosphotyrosine(Syk)HMM predict
485O-linkedHMM predict
505MethylarginineHMM predict
514Phosphothreonine(CDK)HMM predict
625O-linkedHMM predict
646Phosphotyrosine(INSR)HMM predict
655Phosphoserine(ATM)HMM predict
662Phosphoserine(ATM)HMM predict
677O-linkedHMM predict
699Phosphoserine(IKK)HMM predict
709Phosphoserine(CK1)HMM predict
709Phosphoserine(PKC)HMM predict
709Phosphoserine(IKK)HMM predict
709Phosphoserine(PKA)HMM predict
709Phosphoserine(PKA)HMM predict
709Phosphoserine(PKG)HMM predict
709Phosphoserine(CAMK2)HMM predict
722Phosphoserine(IKK)HMM predict
740O-linkedHMM predict
740Phosphoserine(CDC2)HMM predict
750O-linkedHMM predict
750Phosphoserine(ATM)HMM predict
756Phosphoserine(ATM)HMM predict
756O-linkedHMM predict
758PhosphothreonineHMM predict
758O-linkedHMM predict
758Phosphothreonine(MAPK)HMM predict
758Phosphothreonine(CDK)HMM predict
762O-linkedHMM predict
764Phosphoserine(CK1)HMM predict
779N-linkedHMM predict
784Phosphotyrosine(INSR)HMM predict
786Phosphoserine(PKG)HMM predict
799Phosphoserine(PKB)HMM predict
800O-linkedHMM predict
806Phosphoserine(CDC2)HMM predict
857Phosphoserine(ATM)HMM predict
1092Phosphothreonine(PKC)HMM predict
1150Phosphothreonine(PKC)HMM predict
1182ProlineHMM predict
1183AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001020658
  • Location:chr1 31176939-31311150
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 31311244 31311499 255 221
KLF4 hESGSE17917 31322794 31322949 155 11721
Myc K562GSE19551 31316546 31316996 450 5621
Rb SenescentGSE19898 31310934 31311563 629 98
hScc1 BcellGSE12603 31311118 31311499 381 158
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 31174837 31175223 386 1910
CTCF CD4SISSRdata 31174837 31175223 386 1910
CTCF G2GSE9613 31174488 31175327 839 2032
Oct1 HelaGSE14283 31173890 31173923 33 3033
hScc1 BcellGSE12603 31174516 31175006 490 2179
hScc1 CdLSGSE12603 31174748 31175296 548 1918
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 31307756 31307792 36 0
ER Fulvestrant-MCF7GSE14664 31307756 31307792 36 0
FOXA1 MCF7GSE15244 31247232 31247909 677 0
H3K4me3 colorectalcancer 31309565 31310121 556 0
H3ac HepG2E 31309774 31311059 1285 0
NFkBII GM15510GSE19485 31310176 31311540 1364 0
Oct1 H2O2-HelaGSE14283 31271174 31271207 33 0
Oct1 H2O2-HelaGSE14283 31307766 31307794 28 0
Oct1 HelaGSE14283 31268224 31268256 32 0
Oct1 HelaGSE14283 31271174 31271205 31 0
Oct1 HelaGSE14283 31302314 31302351 37 0
Oct1 HelaGSE14283 31307713 31307794 81 0
P300 T30-glioblastomaGSE21026 31310179 31311691 1512 0
PHF8 HeLaGSE20725 31310489 31311695 1206 0
PHF8 Hs68minusFBSGSE20725 31310565 31311465 900 0
PHF8 Hs68plusFBSGSE20725 31310108 31311626 1518 0
RARA MCF7GSE15244 31300577 31301294 717 0
TAF k562GSE8489 31308087 31311304 3217 0
TFAP2C MCF7GSE21234 31252726 31253232 506 0
USF2 HepG2E 31310121 31310965 844 0
hScc1 BcellGSE12603 31179042 31179517 475 0
hScc1 BcellGSE12603 31310323 31310652 329 0
p130 QuiescentGSE19898 31310355 31311320 965 0
p130 SenescentGSE19898 31310523 31311456 933 0
p130 shRbQuiescentGSE19898 31310358 31311283 925 0
p130 shRbSenescentGSE19898 31310588 31311372 784 0
p63 keratinocytesGSE17611 31292707 31293522 815 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-221 hsa-mir-221 X 20818387
hsa-miR-221* hsa-mir-221 X 20818387
hsa-miR-222 hsa-mir-222 X 20818387
hsa-miR-222* hsa-mir-222 X 20818387
hsa-miR-410 hsa-mir-410 14 20860814
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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