AutismKB 2.0

Annotation Detail for CD74


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Basic Information Top
Gene Symbol:CD74 ( DHLAG,HLADG,II,Ia-GAMMA )
Gene Full Name: CD74 molecule, major histocompatibility complex, class II invariant chain
Band: 5q33.1
Quick LinksEntrez ID:972; OMIM: 142790; Uniprot ID:HG2A_HUMAN; ENSEMBL ID: ENSG00000019582; HGNC ID: 1697
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
25Phosphoserine (By similarity).
130N-linked (GlcNAc...).
136N-linked (GlcNAc...).
256N-linked (GlcNAc...).
282O-linked (Xyl...) (glycosaminoglycan)
Location(AA) Modifications Resource
25PhosphoserinePhospho.ELM 6.0
42PhosphoserinePhospho.ELM 6.0
45PhosphoserinePhospho.ELM 6.0
130N-likedOGlycBase6.0
130N-linked (GlcNAc...).Swiss-Prot 53.0
136N-linked (GlcNAc...).Swiss-Prot 53.0
136N-likedOGlycBase6.0
203O-linkedOGlycBase6.0
282O-linked (Xyl...) (glycosaminoglycan)(Potential).Swiss-Prot 53.0
282O-linkedOGlycBase6.0
Location(AA) Modification Resource
8Phosphoserine(PKB)HMM predict
130N-linkedHMM predict
136N-linkedHMM predict
161Phosphoserine(IKK)HMM predict
238Phosphotyrosine(INSR)HMM predict
256N-linkedHMM predict
262N-linkedHMM predict
270N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001025158
  • Location:chr5 149761393-149772524
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149781737 149782104 367 9396
CTCF G2GSE9613 149787967 149788376 409 15647
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21668 EST chr5 149761494 149761861 290 mRNA CD74 chr5 149761396 149772511Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018