AutismKB 2.0

Annotation Detail for ZNF646


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Basic Information Top
Gene Symbol:ZNF646 ( KIAA0296 )
Gene Full Name: zinc finger protein 646
Band: 16p11.2
Quick LinksEntrez ID:9726; OMIM: NA; Uniprot ID:ZN646_HUMAN; ENSEMBL ID: ENSG00000167395; HGNC ID: 29004
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
33Phosphoserine(ATM)HMM predict
38Phosphoserine(CK2)HMM predict
43Phosphoserine(CK1)HMM predict
69Phosphothreonine(PKA)HMM predict
133Phosphoserine(CK1)HMM predict
139N-linkedHMM predict
152Phosphoserine(CK1)HMM predict
152Phosphoserine(IKK)HMM predict
208Phosphoserine(CK1)HMM predict
220N-linkedHMM predict
228O-linkedHMM predict
230Phosphoserine(ATM)HMM predict
268S-palmitoylHMM predict
341Phosphoserine(ATM)HMM predict
341Phosphoserine(CK1)HMM predict
352N-linkedHMM predict
360Phosphoserine(CK2)HMM predict
371Phosphotyrosine(EGFR)HMM predict
437O-linkedHMM predict
465Phosphotyrosine(Jak)HMM predict
589Phosphoserine(CK1)HMM predict
605Phosphoserine(CK1)HMM predict
605Phosphoserine(CK2)HMM predict
610O-linkedHMM predict
612Phosphoserine(CDC2)HMM predict
649S-palmitoylHMM predict
707Phosphoserine(ATM)HMM predict
712Phosphoserine(IKK)HMM predict
715Phosphoserine(CDK)HMM predict
803N-linkedHMM predict
805Phosphoserine(CK1)HMM predict
808Phosphoserine(IKK)HMM predict
905Phosphoserine(IKK)HMM predict
972Phosphoserine(CK1)HMM predict
979Phosphoserine(ATM)HMM predict
985O-linkedHMM predict
991Phosphoserine(CDC2)HMM predict
991Phosphoserine(CDK)HMM predict
1084S-palmitoylHMM predict
1232S-palmitoylHMM predict
1235S-palmitoylHMM predict
1263S-palmitoylHMM predict
1284MethylarginineHMM predict
1289Phosphothreonine(PKC)HMM predict
1293Phosphothreonine(PKC)HMM predict
1326Phosphotyrosine(SRC)HMM predict
1326Phosphotyrosine(Jak)HMM predict
1326Phosphotyrosine(INSR)HMM predict
1376MethylarginineHMM predict
1409N-linkedHMM predict
1442Phosphoserine(CDK)HMM predict
1442Phosphoserine(CDC2)HMM predict
1448Phosphoserine(PKG)HMM predict
1473N-linkedHMM predict
1492Phosphoserine(CK1)HMM predict
1515Phosphoserine(CAMK2)HMM predict
1521N-linkedHMM predict
1523Phosphoserine(ATM)HMM predict
1531Phosphoserine(IKK)HMM predict
1534Phosphoserine(ATM)HMM predict
1552N-linkedHMM predict
1572Phosphothreonine(PKC)HMM predict
1612Phosphoserine(ATM)HMM predict
1667Phosphoserine(MAPK)HMM predict
1721N-linkedHMM predict
1775Phosphoserine(PKG)HMM predict
1775Phosphoserine(PKB)HMM predict
1794MethylarginineHMM predict
1812Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014699
  • Location:chr16 30993268-31002326
  • strand:+
No data
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Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30996473 30996786 313 0
CTCF G2GSE9613 30998305 30998873 568 0
GABP k562GSE8489 30992508 30994097 1589 0
GABP k562GSE8489 30994436 30995815 1379 0
H3K4me3 colorectalcancer 30993619 30994097 478 0
H3ac HepG2E 30992729 30994097 1368 0
Oct1 HelaGSE14283 31000636 31000710 74 0
PHF8 293TGSE20725 30993020 30993857 837 0
RNAII Tamoxifen-MCF7GSE14664 31000965 31001065 100 0
Rb QuiescentGSE19898 30993644 30993899 255 0
Rb SenescentGSE19898 30992979 30993708 729 0
Rb shRbSenescenceGSE19898 30993426 30993674 248 0
TAF HelaGSE8489 30993277 30994097 820 0
TAF HelaGSE8489 30994436 30994818 382 0
hScc1 BcellGSE12603 30996658 30997343 685 0
p130 shRbSenescentGSE19898 30993459 30993683 224 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9861 mRNA ZNF646 chr16 30993268 31002332 87 HTC chr16 31002245 31002688Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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