AutismKB 2.0

Annotation Detail for MLL4


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Basic Information Top
Gene Symbol:MLL4 ( HRX2,KIAA0304,MLL2,TRX2,WBP7 )
Gene Full Name: -
Band: 19q13.1
Quick LinksEntrez ID:9757; OMIM: 606834; Uniprot ID:MLL4_HUMAN; ENSEMBL ID: ENSG00000105663; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
159Phosphothreonine.
172Phosphothreonine.
176Phosphothreonine.
320Phosphoserine (By similarity).
351Phosphoserine.
821Phosphoserine.
844Phosphoserine.
861Phosphoserine.
926N6-acetyllysine.
1032Phosphoserine.
1035Phosphoserine.
1164Phosphoserine.
1930Phosphoserine.
1935Phosphothreonine.
2083Phosphothreonine.
2296N6-acetyllysine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014727
  • Location:chr19 40900760-40921617
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T0-glioblastomaGSE21026 40899922 40900658 736 471
VDR GM10855-UnstimGSE22484 40898679 40902174 3495 334
hScc1 CdLSGSE12603 40899092 40901456 2364 487
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 40920257 40920502 245 0
CTCF CD4SISSRdata 40920257 40920502 245 0
H3ac HepG2E 40901254 40902577 1323 0
hScc1 BcellGSE12603 40902511 40902873 362 0
hScc1 BcellGSE12603 40910066 40910410 344 0
hScc1 BcellGSE12603 40915846 40916297 451 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13098 mRNA MLL4 chr19 40900760 40921619 78 EST chr19 40921541 40922271Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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