AutismKB 2.0

Annotation Detail for SPCS2


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Basic Information Top
Gene Symbol:SPCS2 ( KIAA0102,MGC117366 )
Gene Full Name: signal peptidase complex subunit 2 homolog (S. cerevisiae)
Band: 11q13.4
Quick LinksEntrez ID:9789; OMIM: NA; Uniprot ID:SPCS2_HUMAN; ENSEMBL ID: ENSG00000118363; HGNC ID: 28962
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
169N6-acetyllysine.
191N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
14O-linkedHMM predict
24Phosphoserine(IKK)HMM predict
161Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014752
  • Location:chr11 74337980-74366426
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 74318493 74318829 336 19320
CTCF CD4SISSRdata 74318493 74318829 336 19320
ER E2-MCF7GSE14664 74318833 74318893 60 19118
ETS1 JurkatGSE17954 74337193 74338588 1395 90
Fos K562GSE19551 74337245 74338222 977 247
H3ac HepG2E 74336714 74339228 2514 10
Oct1 H2O2-HelaGSE14283 74333631 74333667 36 4332
Oct1 H2O2-HelaGSE14283 74336598 74336651 53 1356
Oct1 HelaGSE14283 74318786 74318896 110 19140
Oct1 HelaGSE14283 74326612 74326648 36 11351
Oct1 HelaGSE14283 74333626 74333668 42 4334
Oct1 HelaGSE14283 74336599 74336637 38 1363
Oct1 HelaGSE14283 74336704 74336739 35 1259
P300 T30-glioblastomaGSE21026 74337206 74338525 1319 115
PHF8 HeLaGSE20725 74337389 74338450 1061 61
hScc1 BcellGSE12603 74318126 74319176 1050 19330
hScc1 CdLSGSE12603 74317792 74319001 1209 19584
hScc1 G2GSE9613 74318089 74318794 705 19539
p63 keratinocytesGSE17611 74331255 74332625 1370 6041
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 74370478 74370505 27 4065
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 74337605 74338438 833 0
GATA3 MCF7GSE15244 74363618 74363808 190 0
H3K4me3 colorectalcancer 74338186 74339228 1042 0
H3ac HepG2E 74340538 74340893 355 0
Oct1 HelaGSE14283 74348459 74348490 31 0
Oct1 HelaGSE14283 74349030 74349098 68 0
Oct1 HelaGSE14283 74353243 74353273 30 0
Oct1 HelaGSE14283 74353803 74353840 37 0
RARG MCF7GSE15244 74337844 74338511 667 0
TAF HelaGSE8489 74337748 74338690 942 0
TAF k562GSE8489 74337775 74339035 1260 0
USF1 HepG2E 74336752 74339228 2476 0
USF2 HepG2E 74336944 74339035 2091 0
p130 SenescentGSE19898 74337755 74338554 799 0
p130 shRbQuiescentGSE19898 74337660 74338313 653 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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