AutismKB 2.0

Annotation Detail for CUL7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CUL7 ( KIAA0076,dJ20C7.5 )
Gene Full Name: cullin 7
Band: 6p21.1
Quick LinksEntrez ID:9820; OMIM: 609577; Uniprot ID:CUL7_HUMAN; ENSEMBL ID: ENSG00000044090; HGNC ID: 21024
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
329Phosphoserine.
339Phosphoserine.
Location(AA) Modifications Resource
1576Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in NEDD8) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
7Phosphotyrosine(EGFR)HMM predict
75Phosphotyrosine(INSR)HMM predict
147Phosphotyrosine(EGFR)HMM predict
204Phosphoserine(ATM)HMM predict
268N-linkedHMM predict
278N-linkedHMM predict
286Phosphoserine(CK1)HMM predict
322Phosphoserine(CDC2)HMM predict
322PhosphoserineHMM predict
326Phosphoserine(ATM)HMM predict
326Phosphoserine(CDC2)HMM predict
389Phosphotyrosine(INSR)HMM predict
389SulfotyrosineHMM predict
552N-linkedHMM predict
579Phosphotyrosine(EGFR)HMM predict
614Phosphoserine(ATM)HMM predict
614Phosphoserine(IKK)HMM predict
614O-linkedHMM predict
619Phosphothreonine(MAPK)HMM predict
619Phosphothreonine(CDK)HMM predict
643Phosphoserine(CK1)HMM predict
679N-linkedHMM predict
736Phosphothreonine(PKA)HMM predict
737Phosphoserine(CK1)HMM predict
868N-linkedHMM predict
900Phosphotyrosine(INSR)HMM predict
900Phosphotyrosine(SRC)HMM predict
912O-linkedHMM predict
915Phosphoserine(CK1)HMM predict
937N-linkedHMM predict
1006Phosphoserine(CK1)HMM predict
1048Phosphoserine(MAPK)HMM predict
1053N-linkedHMM predict
1056Phosphoserine(MAPK)HMM predict
1097Phosphothreonine(PKA)HMM predict
1115Phosphothreonine(MAPK)HMM predict
1115O-linkedHMM predict
1122N-linkedHMM predict
1142N-linkedHMM predict
1181N-linkedHMM predict
1268SulfotyrosineHMM predict
1310Phosphothreonine(PKC)HMM predict
1310Phosphothreonine(CK2)HMM predict
1311Phosphoserine(CK1)HMM predict
1353Phosphoserine(CK2)HMM predict
1382SulfotyrosineHMM predict
1382Phosphotyrosine(Syk)HMM predict
1429Phosphotyrosine(Syk)HMM predict
1430N-linkedHMM predict
1432Phosphoserine(ATM)HMM predict
1460N-linkedHMM predict
1549Phosphotyrosine(SRC)HMM predict
1619O-linkedHMM predict
1651Phosphothreonine(PKC)HMM predict
1664O-linkedHMM predict
1665O-linkedHMM predict
1689O-linkedHMM predict
1691O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014780
  • Location:chr6 43113333-43129631
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 SenescentGSE19898 43129398 43129905 507 20
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 43113359 43113673 314 0
CTCF G2GSE9613 43120350 43121069 719 0
CTCF G2GSE9613 43122231 43122536 305 0
CTCF G2GSE9613 43123017 43123453 436 0
CTCF G2GSE9613 43123759 43123974 215 0
CTCF G2GSE9613 43125455 43125603 148 0
CTCF G2GSE9613 43128250 43129852 1602 0
ETS1 JurkatGSE17954 43129067 43130193 1126 0
H3ac HepG2E 43125971 43127994 2023 0
H3ac HepG2E 43128423 43129267 844 0
PHF8 293TGSE20725 43129075 43129949 874 0
PHF8 HeLaGSE20725 43128641 43129699 1058 0
Rb QuiescentGSE19898 43128846 43128971 125 0
hScc1 BcellGSE12603 43113639 43113902 263 0
hScc1 BcellGSE12603 43115140 43115395 255 0
hScc1 BcellGSE12603 43129267 43129852 585 0
hScc1 G2GSE9613 43128739 43129995 1256 0
p130 QuiescentGSE19898 43129080 43129352 272 0
p130 SenescentGSE19898 43128936 43129349 413 0
p130 shRbSenescentGSE19898 43128938 43129384 446 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22616 EST chr6 43103141 43116440 294 mRNA CUL7 chr6 43113333 43129632Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved