AutismKB 2.0

Annotation Detail for LRBA


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Basic Information Top
Gene Symbol:LRBA ( BGL,CDC4L,DKFZp686A09128,DKFZp686K03100,DKFZp686P2258,FLJ16600,FLJ25686,LAB300,LBA,MGC72098 )
Gene Full Name: LPS-responsive vesicle trafficking, beach and anchor containing
Band: 4q31.3
Quick LinksEntrez ID:987; OMIM: 606453; Uniprot ID:LRBA_HUMAN; ENSEMBL ID: ENSG00000198589; HGNC ID: 1742
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
10Phosphoserine.
904Phosphotyrosine (By similarity).
979Phosphoserine.
1005Phosphoserine (By similarity).
1016Phosphotyrosine.
1118Phosphoserine.
1120Phosphothreonine.
1135Phosphoserine.
1667Phosphothreonine.
1787Phosphoserine.
2116N6-acetyllysine.
2117N6-acetyllysine.
Location(AA) Modifications Resource
10Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphoserine(CDC2)HMM predict
10Phosphoserine(CDK)HMM predict
34Phosphoserine(PKG)HMM predict
163N-linkedHMM predict
165Phosphothreonine(PKC)HMM predict
335N-linkedHMM predict
389Phosphothreonine(PKC)HMM predict
439N-linkedHMM predict
490Phosphoserine(ATM)HMM predict
536Phosphoserine(CK1)HMM predict
582Phosphothreonine(CDC2)HMM predict
607Phosphothreonine(PKC)HMM predict
810Phosphoserine(CK1)HMM predict
851N-linkedHMM predict
852N-linkedHMM predict
856N-linkedHMM predict
906C-linkedHMM predict
909C-linkedHMM predict
917Phosphoserine(CK1)HMM predict
979Phosphoserine(CDC2)HMM predict
992N-linkedHMM predict
1000Phosphoserine(CK1)HMM predict
1016Phosphotyrosine(INSR)HMM predict
1016Phosphotyrosine(SRC)HMM predict
1040N-linkedHMM predict
1044N-linkedHMM predict
1081Phosphoserine(IKK)HMM predict
1084Phosphoserine(CDC2)HMM predict
1084Phosphoserine(MAPK)HMM predict
1091Phosphoserine(CK2)HMM predict
1110Phosphotyrosine(EGFR)HMM predict
1110Phosphotyrosine(INSR)HMM predict
1110Phosphotyrosine(Syk)HMM predict
1110SulfotyrosineHMM predict
1135Phosphoserine(CDC2)HMM predict
1135Phosphoserine(ATM)HMM predict
1183O-linkedHMM predict
1187O-linkedHMM predict
1191O-linkedHMM predict
1191Phosphoserine(IKK)HMM predict
1217N-linkedHMM predict
1299Phosphoserine(PKA)HMM predict
1299Phosphoserine(PKG)HMM predict
1310N-linkedHMM predict
1346N-linkedHMM predict
1350N-linkedHMM predict
1433Phosphoserine(IKK)HMM predict
1435Phosphoserine(CK1)HMM predict
1562Phosphoserine(IKK)HMM predict
1572N-linkedHMM predict
1584O-linkedHMM predict
1585O-linkedHMM predict
1587O-linkedHMM predict
1594Phosphoserine(CK1)HMM predict
1594Phosphoserine(CK2)HMM predict
1594Phosphoserine(IKK)HMM predict
1596Phosphoserine(CK1)HMM predict
1599Phosphoserine(PKC)HMM predict
1605Phosphoserine(PKG)HMM predict
1605Phosphoserine(CAMK2)HMM predict
1605Phosphoserine(PKA)HMM predict
1617O-linkedHMM predict
1622O-linkedHMM predict
1631O-linkedHMM predict
1645Phosphoserine(CK1)HMM predict
1651Phosphoserine(CDC2)HMM predict
1651Phosphoserine(CDK)HMM predict
1667Phosphothreonine(MAPK)HMM predict
1733O-linkedHMM predict
1736O-linkedHMM predict
1741N-linkedHMM predict
1742O-linkedHMM predict
1747N-linkedHMM predict
1767Phosphoserine(CDK)HMM predict
1770Phosphoserine(IKK)HMM predict
1849Phosphoserine(CK1)HMM predict
1859Phosphoserine(ATM)HMM predict
1885Phosphoserine(CAMK2)HMM predict
1919Phosphoserine(IKK)HMM predict
2028Phosphothreonine(CK2)HMM predict
2039Phosphoserine(PKG)HMM predict
2042Phosphoserine(ATM)HMM predict
2050Phosphoserine(CK2)HMM predict
2064Phosphoserine(CK1)HMM predict
2079Phosphoserine(IKK)HMM predict
2081Phosphoserine(IKK)HMM predict
2098Phosphoserine(IKK)HMM predict
2198Phosphoserine(PKA)HMM predict
2198Phosphoserine(PKA)HMM predict
2198Phosphoserine(PKG)HMM predict
2198Phosphoserine(CAMK2)HMM predict
2198PhosphoserineHMM predict
2210N-linkedHMM predict
2288SulfotyrosineHMM predict
2342Phosphoserine(CDK)HMM predict
2354Phosphothreonine(CK2)HMM predict
2477Phosphothreonine(MAPK)HMM predict
2479Phosphoserine(ATM)HMM predict
2491O-linkedHMM predict
2587Phosphothreonine(PKA)HMM predict
2684Phosphoserine(CK2)HMM predict
2698Phosphotyrosine(Jak)HMM predict
2716Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006726
  • Location:chr4 151405262-152156098
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 152155661 152156871 1210 168
FOXA1 MCF7GSE15244 152175728 152176245 517 19888
FOXA1 eGFPGSE10845 152175728 152176245 517 19888
Myc K562GSE19551 152172464 152173091 627 16679
PHF8 293TGSE20725 152155266 152157171 1905 120
PHF8 HeLaGSE20725 152155422 152156944 1522 85
TFAP2C MCF7GSE21234 152156447 152157010 563 630
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 152101528 152101687 159 0
CTCF CD4SISSRdata 152101528 152101687 159 0
CTCF G2GSE9613 151438534 151438753 219 0
CTCF G2GSE9613 151720406 151720741 335 0
CTCF G2GSE9613 152101335 152101853 518 0
ER E2-MCF7GSE14664 151574212 151574300 88 0
ER E2-MCF7GSE14664 151996873 151996990 117 0
ER Fulvestrant-MCF7GSE14664 151996879 151996931 52 0
Fos K562GSE19551 151442951 151443663 712 0
Fos K562GSE19551 151488647 151489043 396 0
FoxA1 MCF7MACSdata 151603294 151603474 180 0
FoxA1 MCF7MACSdata 151855458 151855671 213 0
H3K4me3 colorectalcancer 152154666 152155762 1096 0
H3ac HepG2E 152154513 152155936 1423 0
Myc K562GSE19551 151713553 151714094 541 0
Nanog ESGSE20650 151455784 151456317 533 0
Nanog ESGSE20650 151507835 151508342 507 0
Nanog ESGSE20650 151732044 151732491 447 0
Nanog ESGSE20650 151835103 151835464 361 0
Nanog hESGSE18292 151835109 151835330 221 0
Oct1 H2O2-HelaGSE14283 151454928 151454960 32 0
Oct1 H2O2-HelaGSE14283 151473409 151473438 29 0
Oct1 H2O2-HelaGSE14283 151601980 151602048 68 0
Oct1 H2O2-HelaGSE14283 151940958 151940998 40 0
Oct1 H2O2-HelaGSE14283 152079889 152079932 43 0
Oct1 HelaGSE14283 151417637 151417701 64 0
Oct1 HelaGSE14283 151418730 151418770 40 0
Oct1 HelaGSE14283 151418814 151418903 89 0
Oct1 HelaGSE14283 151454929 151454962 33 0
Oct1 HelaGSE14283 151497846 151497892 46 0
Oct1 HelaGSE14283 151503693 151503751 58 0
Oct1 HelaGSE14283 151517542 151517573 31 0
Oct1 HelaGSE14283 151601976 151602064 88 0
Oct1 HelaGSE14283 151676511 151676573 62 0
Oct1 HelaGSE14283 151750356 151750417 61 0
Oct1 HelaGSE14283 151750452 151750545 93 0
Oct1 HelaGSE14283 151871648 151871684 36 0
Oct1 HelaGSE14283 151891454 151891513 59 0
Oct1 HelaGSE14283 151898848 151898941 93 0
Oct1 HelaGSE14283 151940958 151940998 40 0
Oct1 HelaGSE14283 151991707 151991742 35 0
Oct1 HelaGSE14283 151996835 151996941 106 0
Oct1 HelaGSE14283 152017897 152017927 30 0
Oct1 HelaGSE14283 152022727 152022769 42 0
Oct1 HelaGSE14283 152073257 152073287 30 0
Oct4 ESGSE20650 151507927 151508297 370 0
Oct4 hESGSE17917 151732151 151732447 296 0
P300 T30-glioblastomaGSE21026 151488614 151489078 464 0
Pol3 GM12878GSE19551 151676424 151676738 314 0
RARA MCF7GSE15244 151709492 151710832 1340 0
TFAP2C MCF7GSE21234 151526320 151526626 306 0
TFAP2C MCF7GSE21234 152101510 152101775 265 0
hScc1 BcellGSE12603 151438406 151438790 384 0
hScc1 BcellGSE12603 151564114 151564410 296 0
hScc1 BcellGSE12603 151720443 151720779 336 0
hScc1 CdLSGSE12603 151438253 151438790 537 0
hScc1 G2GSE9613 152154948 152156627 1679 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20321 mRNA chr4 151857845 151860302 228 HTC LRBA chr4 151543417 151860479Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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