AutismKB 2.0

Annotation Detail for FCHSD2


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Basic Information Top
Gene Symbol:FCHSD2 ( KIAA0769,NWK,SH3MD3 )
Gene Full Name: FCH and double SH3 domains 2
Band: 11q13.4
Quick LinksEntrez ID:9873; OMIM: NA; Uniprot ID:FCSD2_HUMAN; ENSEMBL ID: ENSG00000137478; HGNC ID: 29114
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
683Phosphoserine (By similarity).
Location(AA) Modifications Resource
683Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
43Phosphoserine(PKC)HMM predict
43Phosphoserine(ATM)HMM predict
80SulfotyrosineHMM predict
80Phosphotyrosine(INSR)HMM predict
80Phosphotyrosine(Syk)HMM predict
118Phosphothreonine(PKC)HMM predict
202Phosphoserine(CK1)HMM predict
225Phosphotyrosine(Jak)HMM predict
273N-linkedHMM predict
333Phosphothreonine(PKA)HMM predict
333Phosphothreonine(PKC)HMM predict
429O-linkedHMM predict
431N-linkedHMM predict
461Phosphoserine(CK1)HMM predict
462Phosphoserine(CDK)HMM predict
462Phosphoserine(CDC2)HMM predict
466Phosphothreonine(PKC)HMM predict
483Phosphoserine(ATM)HMM predict
524Phosphotyrosine(EGFR)HMM predict
532Phosphoserine(IKK)HMM predict
552N-linkedHMM predict
554Phosphothreonine(CK2)HMM predict
578SulfotyrosineHMM predict
582Phosphothreonine(CK2)HMM predict
628Phosphoserine(CK1)HMM predict
644Phosphoserine(CDC2)HMM predict
646Phosphoserine(CDC2)HMM predict
646Phosphoserine(ATM)HMM predict
646O-linkedHMM predict
652O-linkedHMM predict
664O-linkedHMM predict
665Phosphoserine(CDC2)HMM predict
665PhosphoserineHMM predict
665Phosphoserine(ATM)HMM predict
667Phosphotyrosine(Syk)HMM predict
669Phosphoserine(CDC2)HMM predict
669Phosphoserine(CDK)HMM predict
669Phosphoserine(CDK)HMM predict
681Phosphoserine(CDC2)HMM predict
683Phosphoserine(PKC)HMM predict
683Phosphoserine(PKB)HMM predict
697Phosphoserine(ATM)HMM predict
700O-linkedHMM predict
703Phosphothreonine(CDK)HMM predict
708Phosphotyrosine(SRC)HMM predict
722O-linkedHMM predict
732IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014824
  • Location:chr11 72225438-72530738
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 72529607 72532614 3007 372
H3ac HepG2E 72531579 72532667 1088 1385
H3ac HepG2E 72535530 72536045 515 5049
H3ac HepG2E 72541782 72542689 907 11497
H3ac HepG2E 72544502 72546337 1835 14681
H3ac HepG2E 72548054 72548505 451 17541
NFkBII GM10847GSE19485 72529387 72532883 3496 397
NFkBII GM12878GSE19485 72535152 72537978 2826 5827
NFkBII GM12892GSE19485 72529039 72532965 3926 264
NFkBII GM12892GSE19485 72535316 72537676 2360 5758
NFkBII GM18526GSE19485 72529039 72532857 3818 210
NRSF pAbJurkat 72530636 72531113 477 136
NRSF pAbJurkat 72536461 72537085 624 6035
NRSF pAbJurkat 72548086 72548505 419 17557
Oct1 H2O2-HelaGSE14283 72535024 72535062 38 4305
Oct1 HelaGSE14283 72535027 72535064 37 4307
Rb GrowingGSE19898 72547144 72547358 214 16513
Rb SenescentGSE19898 72531004 72531561 557 544
USF1 HepG2E 72531476 72532667 1191 1333
USF2 HepG2E 72531751 72532667 916 1471
hScc1 BcellGSE12603 72530300 72532076 1776 450
hScc1 BcellGSE12603 72542906 72543347 441 12388
hScc1 CdLSGSE12603 72536392 72536655 263 5785
p130 shRbSenescentGSE19898 72531034 72531556 522 557
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 72237618 72237916 298 0
CTCF CD4GSE12889 72313300 72313650 350 0
CTCF CD4SISSRdata 72237618 72237916 298 0
CTCF CD4SISSRdata 72313300 72313650 350 0
CTCF JurkatGSE12889 72237545 72237825 280 0
ER E2-MCF7GSE14664 72234517 72234619 102 0
ER E2-MCF7GSE14664 72272483 72272552 69 0
ER E2-MCF7GSE14664 72296965 72296997 32 0
ER E2-MCF7GSE14664 72363152 72363184 32 0
ER Fulvestrant-MCF7GSE14664 72234523 72234607 84 0
ER Fulvestrant-MCF7GSE14664 72272484 72272549 65 0
ER Fulvestrant-MCF7GSE14664 72277851 72277909 58 0
ER Fulvestrant-MCF7GSE14664 72368576 72368609 33 0
FOXA1 DLD1GSE12801 72461311 72462191 880 0
FOXA1 MCF7GSE15244 72461347 72462011 664 0
FOXA1 MCF7GSE15244 72529126 72530231 1105 0
FoxA1 MCF7MACSdata 72461468 72461993 525 0
H3ac HepG2E 72528469 72530185 1716 0
NFkBII GM12878GSE19485 72527473 72532969 5496 0
Nanog ESGSE20650 72401095 72401676 581 0
Nanog hESGSE18292 72339439 72339952 513 0
Nanog hESGSE18292 72400943 72401599 656 0
Oct1 H2O2-HelaGSE14283 72333023 72333104 81 0
Oct1 H2O2-HelaGSE14283 72369838 72369869 31 0
Oct1 H2O2-HelaGSE14283 72371788 72371819 31 0
Oct1 H2O2-HelaGSE14283 72381592 72381621 29 0
Oct1 H2O2-HelaGSE14283 72384915 72384955 40 0
Oct1 H2O2-HelaGSE14283 72446833 72446870 37 0
Oct1 H2O2-HelaGSE14283 72453217 72453247 30 0
Oct1 H2O2-HelaGSE14283 72515324 72515353 29 0
Oct1 H2O2-HelaGSE14283 72529898 72529927 29 0
Oct1 HelaGSE14283 72277822 72277910 88 0
Oct1 HelaGSE14283 72293399 72293447 48 0
Oct1 HelaGSE14283 72296209 72296243 34 0
Oct1 HelaGSE14283 72324505 72324561 56 0
Oct1 HelaGSE14283 72333032 72333106 74 0
Oct1 HelaGSE14283 72340421 72340494 73 0
Oct1 HelaGSE14283 72344305 72344337 32 0
Oct1 HelaGSE14283 72350509 72350539 30 0
Oct1 HelaGSE14283 72363153 72363184 31 0
Oct1 HelaGSE14283 72369838 72369874 36 0
Oct1 HelaGSE14283 72371787 72371820 33 0
Oct1 HelaGSE14283 72384913 72384957 44 0
Oct1 HelaGSE14283 72407989 72408025 36 0
Oct1 HelaGSE14283 72425585 72425622 37 0
Oct1 HelaGSE14283 72435952 72435994 42 0
Oct1 HelaGSE14283 72446833 72446867 34 0
Oct1 HelaGSE14283 72499753 72499831 78 0
Oct1 HelaGSE14283 72515324 72515353 29 0
Oct1 HelaGSE14283 72516048 72516088 40 0
Oct1 HelaGSE14283 72518959 72518989 30 0
P300 T30-glioblastomaGSE21026 72229060 72230185 1125 0
P300 T30-glioblastomaGSE21026 72364545 72365107 562 0
PHF8 293TGSE20725 72529748 72531661 1913 0
PHF8 HeLaGSE20725 72529404 72531892 2488 0
RARA MCF7GSE15244 72529126 72529595 469 0
RNAII Tamoxifen-MCF7GSE14664 72238358 72238400 42 0
RNAII Tamoxifen-MCF7GSE14664 72277866 72277913 47 0
TAF HelaGSE8489 72514424 72514631 207 0
TFAP2C MCF7GSE21234 72503022 72503938 916 0
hScc1 CdLSGSE12603 72313401 72313793 392 0
hScc1 CdLSGSE12603 72436734 72437065 331 0
hScc1 CdLSGSE12603 72525972 72526472 500 0
hScc1 CdLSGSE12603 72529089 72531821 2732 0
p130 QuiescentGSE19898 72529326 72529530 204 0
p130 SenescentGSE19898 72529203 72529684 481 0
p130 shRbQuiescentGSE19898 72529085 72529702 617 0
p130 shRbSenescentGSE19898 72529247 72529655 408 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4864 mRNA chr11 72203098 72232363 483 mRNA FCHSD2 chr11 72225438 72530739Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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