Annotation Detail for TLK1
Basic Information Top
| Gene Symbol: | TLK1 ( KIAA0137,PKU-beta ) |
|---|---|
| Gene Full Name: | tousled-like kinase 1 |
| Band: | 2q31.1 |
| Quick Links | Entrez ID:9874; OMIM: 608438; Uniprot ID:TLK1_HUMAN; ENSEMBL ID: ENSG00000198586; HGNC ID: 11841 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 74 | Phosphoserine. | |
| 75 | Phosphothreonine. | |
| 77 | Phosphoserine. | |
| 78 | Phosphothreonine. | |
| 80 | Phosphoserine. | |
| 133 | Phosphoserine. | |
| 138 | Phosphoserine. | |
| 158 | Phosphoserine. | |
| 159 | Phosphoserine. | |
| 179 | Phosphothreonine. | |
| 190 | Phosphoserine. | |
| 741 | Phosphoserine. | |
| 743 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 159 | Phosphoserine. | Swiss-Prot 53.0 |
| 159 | Phosphoserine | Phospho.ELM 6.0 |
| 179 | Phosphothreonine. | Swiss-Prot 53.0 |
| 190 | Phosphoserine. | Swiss-Prot 53.0 |
| 743 | Phosphoserine. | Swiss-Prot 53.0 |
| 743 | Phosphoserine (CHK1) | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 7 | Phosphoserine(CK2) | HMM predict |
| 9 | Phosphoserine(CK1) | HMM predict |
| 9 | Phosphoserine(IKK) | HMM predict |
| 17 | Phosphoserine(IKK) | HMM predict |
| 20 | O-linked | HMM predict |
| 21 | O-linked | HMM predict |
| 22 | Phosphoserine(ATM) | HMM predict |
| 22 | Phosphoserine(MAPK) | HMM predict |
| 22 | Phosphoserine(CDK) | HMM predict |
| 22 | Phosphoserine(CDC2) | HMM predict |
| 24 | Phosphothreonine(MAPK) | HMM predict |
| 24 | O-linked | HMM predict |
| 24 | Phosphothreonine(CDK) | HMM predict |
| 36 | N-linked | HMM predict |
| 38 | Phosphothreonine(CDC2) | HMM predict |
| 68 | Phosphothreonine(PKC) | HMM predict |
| 72 | O-linked | HMM predict |
| 74 | O-linked | HMM predict |
| 74 | O-linked | HMM predict |
| 77 | O-linked | HMM predict |
| 78 | O-linked | HMM predict |
| 82 | O-linked | HMM predict |
| 82 | Phosphoserine(ATM) | HMM predict |
| 91 | N-linked | HMM predict |
| 95 | N-linked | HMM predict |
| 105 | Phosphoserine(ATM) | HMM predict |
| 109 | Phosphoserine(CK2) | HMM predict |
| 111 | Phosphothreonine(CDK) | HMM predict |
| 111 | Phosphothreonine(CDC2) | HMM predict |
| 111 | Phosphothreonine | HMM predict |
| 111 | Phosphothreonine(MAPK) | HMM predict |
| 131 | N-linked | HMM predict |
| 134 | Phosphoserine(ATM) | HMM predict |
| 156 | N-linked | HMM predict |
| 159 | Phosphoserine(CDC2) | HMM predict |
| 178 | Phosphoserine(CK1) | HMM predict |
| 178 | Phosphoserine(IKK) | HMM predict |
| 179 | Phosphothreonine(CDK) | HMM predict |
| 182 | Phosphoserine(CDC2) | HMM predict |
| 188 | Phosphoserine(IKK) | HMM predict |
| 188 | Phosphoserine(CDC2) | HMM predict |
| 190 | Phosphoserine(CDC2) | HMM predict |
| 293 | Phosphoserine(PKB) | HMM predict |
| 355 | N-linked | HMM predict |
| 356 | N-linked | HMM predict |
| 471 | Phosphotyrosine(Syk) | HMM predict |
| 481 | Phosphotyrosine(Syk) | HMM predict |
| 490 | N-linked | HMM predict |
| 628 | Phosphoserine(ATM) | HMM predict |
| 677 | N-linked | HMM predict |
| 679 | Phosphoserine(ATM) | HMM predict |
| 741 | Phosphoserine(PKG) | HMM predict |
| 741 | Phosphoserine(PKA) | HMM predict |
| 742 | N-linked | HMM predict |
| 743 | Phosphoserine(PKA) | HMM predict |
| 743 | Phosphoserine | HMM predict |
| 746 | N-linked | HMM predict |
| 755 | Phosphoserine(IKK) | HMM predict |
| 755 | Phosphoserine(CDC2) | HMM predict |
| 757 | Phosphothreonine(CDK) | HMM predict |
| 757 | Phosphothreonine(MAPK) | HMM predict |
| 757 | O-linked | HMM predict |
| 757 | Phosphothreonine | HMM predict |
| 760 | O-linked | HMM predict |
- RefSeq ID: NM_012290
- Location:chr2 171556815-171725205
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| TAF | k562 | GSE8489 | 171726011 | 171726912 | 901 | 1256 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| NRSF | Jurkat | SISSRdata | 171548992 | 171549279 | 287 | 7680 |
| Nanog | hES | GSE18292 | 171548861 | 171549195 | 334 | 7788 |
| Nanog | hES | GSE18292 | 171556253 | 171556467 | 214 | 456 |
| Sox2 | hES | GSE18292 | 171548937 | 171549376 | 439 | 7659 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | T0-glioblastoma | GSE21026 | 171707978 | 171708484 | 506 | 0 |
| CBP | T30-glioblastoma | GSE21026 | 171707999 | 171708466 | 467 | 0 |
| CTCF | CD4 | GSE12889 | 171651582 | 171651925 | 343 | 0 |
| CTCF | CD4 | GSE12889 | 171724016 | 171724337 | 321 | 0 |
| CTCF | CD4 | SISSRdata | 171651582 | 171651925 | 343 | 0 |
| CTCF | CD4 | SISSRdata | 171724016 | 171724337 | 321 | 0 |
| CTCF | G2 | GSE9613 | 171724104 | 171725245 | 1141 | 0 |
| ER | E2-MCF7 | GSE14664 | 171565361 | 171565396 | 35 | 0 |
| H3K4me3 | colorectal | cancer | 171723965 | 171724502 | 537 | 0 |
| H3ac | HepG2 | E | 171722915 | 171724848 | 1933 | 0 |
| KLF4 | hES | GSE17917 | 171724818 | 171725034 | 216 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 171713932 | 171713960 | 28 | 0 |
| Oct1 | Hela | GSE14283 | 171568753 | 171568787 | 34 | 0 |
| Oct1 | Hela | GSE14283 | 171693350 | 171693378 | 28 | 0 |
| Stat6 | IL-4-hr1 | GSE17850 | 171646111 | 171646760 | 649 | 0 |
| TAF | k562 | GSE8489 | 171698843 | 171699163 | 320 | 0 |
| TAF | k562 | GSE8489 | 171722696 | 171725245 | 2549 | 0 |
| hScc1 | Bcell | GSE12603 | 171723745 | 171725245 | 1500 | 0 |
| hScc1 | CdLS | GSE12603 | 171723780 | 171725245 | 1465 | 0 |
Validated miRNA targets