AutismKB 2.0

Annotation Detail for RBM19


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Basic Information Top
Gene Symbol:RBM19 ( DKFZp586F1023,KIAA0682 )
Gene Full Name: RNA binding motif protein 19
Band: 12q24.13-q24.21
Quick LinksEntrez ID:9904; OMIM: NA; Uniprot ID:RBM19_HUMAN; ENSEMBL ID: ENSG00000122965; HGNC ID: 29098
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
174Phosphoserine.
176Phosphoserine.
180Phosphoserine.
949Phosphoserine.
951Phosphoserine.
957Phosphothreonine.
Location(AA) Modifications Resource
174PhosphoserinePhospho.ELM 6.0
176PhosphoserinePhospho.ELM 6.0
180PhosphoserinePhospho.ELM 6.0
949Phosphoserine.Swiss-Prot 53.0
949PhosphoserinePhospho.ELM 6.0
951Phosphoserine.Swiss-Prot 53.0
951PhosphoserinePhospho.ELM 6.0
957Phosphothreonine.Swiss-Prot 53.0
Location(AA) Modification Resource
51PhosphoserineHMM predict
63N-linkedHMM predict
169Phosphotyrosine(Syk)HMM predict
180PhosphoserineHMM predict
180Phosphoserine(CK2)HMM predict
210Phosphotyrosine(Jak)HMM predict
220Phosphoserine(CK2)HMM predict
222Phosphoserine(CK2)HMM predict
223PhosphoserineHMM predict
223Phosphoserine(CK2)HMM predict
224Phosphoserine(CK2)HMM predict
224Phosphoserine(CK1)HMM predict
229Phosphoserine(CK1)HMM predict
229Phosphoserine(CK2)HMM predict
240Phosphoserine(CK2)HMM predict
247Phosphoserine(CK1)HMM predict
281Phosphothreonine(PKC)HMM predict
304N-linkedHMM predict
309N-linkedHMM predict
331N-linkedHMM predict
379N-linkedHMM predict
413Phosphoserine(CK2)HMM predict
485Phosphoserine(CK2)HMM predict
533N-linkedHMM predict
578Phosphoserine(ATM)HMM predict
612Phosphoserine(PKA)HMM predict
663O-linkedHMM predict
695Phosphothreonine(MAPK)HMM predict
695Phosphothreonine(CDC2)HMM predict
700N-linkedHMM predict
726Phosphoserine(CK1)HMM predict
755Phosphothreonine(PKC)HMM predict
813Phosphothreonine(PKC)HMM predict
818Phosphothreonine(PKC)HMM predict
830Phosphothreonine(PKC)HMM predict
860Phosphothreonine(PKC)HMM predict
923Phosphothreonine(PKA)HMM predict
949Phosphoserine(CK2)HMM predict
949Phosphoserine(CK1)HMM predict
949Phosphoserine(ATM)HMM predict
951Phosphoserine(ATM)HMM predict
951Phosphoserine(CK2)HMM predict
953Phosphoserine(CK1)HMM predict
953Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016196
  • Location:chr12 112744245-112888498
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 112888524 112888922 398 225
CTCF CD4GSE12889 112902807 112903025 218 14418
CTCF CD4SISSRdata 112888524 112888922 398 225
CTCF CD4SISSRdata 112902807 112903025 218 14418
CTCF HelaGSE12889 112888593 112888768 175 182
CTCF JurkatGSE12889 112888533 112888774 241 155
CTCF G2GSE9613 112888249 112888927 678 90
CTCF G2GSE9613 112900385 112900680 295 12034
CTCF G2GSE9613 112902696 112903374 678 14537
GATA3 MCF7GSE15244 112905594 112905957 363 17277
Oct1 HelaGSE14283 112902019 112902053 34 13538
hScc1 BcellGSE12603 112902696 112903374 678 14537
hScc1 CdLSGSE12603 112888497 112888927 430 214
hScc1 CdLSGSE12603 112902696 112903374 678 14537
hScc1 G2GSE9613 112888497 112888903 406 202
hScc1 G2GSE9613 112902696 112903374 678 14537
p130 QuiescentGSE19898 112888410 112888877 467 145
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 112724907 112725341 434 19122
CTCF G2GSE9613 112727345 112727882 537 16632
CTCF G2GSE9613 112737578 112737825 247 6544
CTCF G2GSE9613 112739292 112739947 655 4626
CTCF G2GSE9613 112740927 112741800 873 2882
CTCF G2GSE9613 112742510 112742765 255 1608
CTCF G2GSE9613 112743421 112743755 334 658
Fos K562GSE19551 112731689 112731986 297 12408
NRSF pAbJurkat 112737519 112737933 414 6520
Oct1 H2O2-HelaGSE14283 112731681 112731724 43 12543
Oct1 H2O2-HelaGSE14283 112738716 112738753 37 5511
hScc1 BcellGSE12603 112739368 112739876 508 4624
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 112834983 112835287 304 0
CTCF CD4SISSRdata 112834983 112835287 304 0
CTCF HelaGSE12889 112834864 112835209 345 0
CTCF JurkatGSE12889 112834955 112835167 212 0
CTCF G2GSE9613 112745233 112745529 296 0
CTCF G2GSE9613 112746506 112746689 183 0
CTCF G2GSE9613 112748018 112748269 251 0
CTCF G2GSE9613 112748752 112749632 880 0
CTCF G2GSE9613 112750752 112750903 151 0
CTCF G2GSE9613 112751696 112752402 706 0
CTCF G2GSE9613 112753592 112754119 527 0
CTCF G2GSE9613 112755297 112755538 241 0
CTCF G2GSE9613 112761146 112761283 137 0
CTCF G2GSE9613 112764263 112764415 152 0
CTCF G2GSE9613 112765454 112765839 385 0
CTCF G2GSE9613 112766229 112766741 512 0
CTCF G2GSE9613 112767045 112767604 559 0
CTCF G2GSE9613 112768250 112768428 178 0
CTCF G2GSE9613 112775599 112775773 174 0
CTCF G2GSE9613 112781443 112781703 260 0
CTCF G2GSE9613 112782289 112783141 852 0
CTCF G2GSE9613 112789441 112789618 177 0
CTCF G2GSE9613 112827042 112827346 304 0
CTCF G2GSE9613 112830123 112830424 301 0
CTCF G2GSE9613 112830691 112831285 594 0
CTCF G2GSE9613 112832244 112832687 443 0
CTCF G2GSE9613 112833958 112835295 1337 0
CTCF G2GSE9613 112837235 112837748 513 0
CTCF G2GSE9613 112842056 112842393 337 0
CTCF G2GSE9613 112853565 112853954 389 0
CTCF G2GSE9613 112854629 112854978 349 0
CTCF G2GSE9613 112862468 112862757 289 0
CTCF G2GSE9613 112870273 112870421 148 0
CTCF G2GSE9613 112871333 112871510 177 0
CTCF G2GSE9613 112874126 112874539 413 0
CTCF G2GSE9613 112877284 112877681 397 0
CTCF G2GSE9613 112879800 112879951 151 0
CTCF G2GSE9613 112882838 112883195 357 0
ETS1 JurkatGSE17954 112887981 112889012 1031 0
FOXA1 MCF7GSE15244 112887960 112888569 609 0
GATA3 MCF7GSE15244 112885445 112886335 890 0
Gata1 K562GSE18868 112855036 112855541 505 0
Gata2 K562GSE18868 112854605 112856181 1576 0
H3K4me2 HCT116GSE10453 112887572 112888215 643 0
H3K4me3 colorectalcancer 112887572 112888428 856 0
H3ac HepG2E 112886124 112887019 895 0
H3ac HepG2E 112887572 112888428 856 0
KLF4 hESGSE17917 112752662 112752827 165 0
Myc K562GSE19551 112776514 112776917 403 0
Myc K562GSE19551 112822271 112822685 414 0
Myc K562GSE19551 112834973 112835235 262 0
NRSF pAbJurkat 112753179 112753745 566 0
NRSF pAbJurkat 112853601 112853810 209 0
NRSF pAbJurkat 112867446 112867928 482 0
Nanog hESGSE18292 112851395 112851798 403 0
P300 T0-glioblastomaGSE21026 112752964 112753569 605 0
P300 T30-glioblastomaGSE21026 112752986 112753591 605 0
P300 T30-glioblastomaGSE21026 112887984 112888946 962 0
RARA MCF7GSE15244 112887572 112888903 1331 0
RARG MCF7GSE15244 112796381 112796808 427 0
RARG MCF7GSE15244 112847966 112848151 185 0
RARG MCF7GSE15244 112887789 112888903 1114 0
Rb GrowingGSE19898 112855716 112855997 281 0
TAF HelaGSE8489 112887572 112888457 885 0
TAF k562GSE8489 112887572 112889218 1646 0
TFAP2C MCF7GSE21234 112785632 112786378 746 0
USF1 HepG2E 112887572 112889413 1841 0
USF2 HepG2E 112887572 112888651 1079 0
hScc1 BcellGSE12603 112745350 112745879 529 0
hScc1 BcellGSE12603 112753745 112753950 205 0
hScc1 BcellGSE12603 112827182 112827346 164 0
hScc1 BcellGSE12603 112834461 112835272 811 0
hScc1 BcellGSE12603 112837548 112837777 229 0
hScc1 BcellGSE12603 112845668 112845861 193 0
hScc1 BcellGSE12603 112852068 112852389 321 0
hScc1 BcellGSE12603 112854514 112854848 334 0
hScc1 CdLSGSE12603 112834900 112835506 606 0
hScc1 G2GSE9613 112745233 112745529 296 0
hScc1 G2GSE9613 112748788 112749448 660 0
hScc1 G2GSE9613 112834900 112835295 395 0
p130 QuiescentGSE19898 112855682 112855837 155 0
p130 shRbQuiescentGSE19898 112887954 112888657 703 0
p130 shRbSenescentGSE19898 112888140 112888737 597 0
p63 keratinocytesGSE17611 112780783 112781516 733 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
887 Unknown pSILAC let-7b RBM19 down 50-25% 18668040
921 Unknown pSILAC LNA_let-7b RBM19 up <25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000122965 n_a n_a n_a "lymphoblast, lymphocyte" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000122965 n_a n_a n_a "lymphoblast, lymphocyte" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6649 EST chr12 112801060 112801780 720 mRNA RBM19 chr12 112722582 112866836 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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