AutismKB 2.0

Annotation Detail for G3BP2


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Basic Information Top
Gene Symbol:G3BP2 ( - )
Gene Full Name: GTPase activating protein (SH3 domain) binding protein 2
Band: 4q21.1
Quick LinksEntrez ID:9908; OMIM: NA; Uniprot ID:G3BP2_HUMAN; ENSEMBL ID: ENSG00000138757; HGNC ID: 30291
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
141Phosphoserine.
149Phosphoserine.
225Phosphoserine.
226Phosphothreonine.
227Phosphothreonine.
235Phosphoserine.
457Omega-N-methylated arginine.
468Omega-N-methylated arginine.
Location(AA) Modifications Resource
141Phosphoserine.Swiss-Prot 53.0
149Phosphoserine.Swiss-Prot 53.0
225Phosphoserine (By similarity).Swiss-Prot 53.0
227Phosphothreonine.Swiss-Prot 53.0
457Omega-N-methylated arginine.Swiss-Prot 53.0
468Omega-N-methylated arginine.Swiss-Prot 53.0
Location(AA) Modification Resource
37N-linkedHMM predict
69N-linkedHMM predict
149Phosphoserine(CK1)HMM predict
149PhosphoserineHMM predict
149Phosphoserine(CK2)HMM predict
163O-linkedHMM predict
163Phosphoserine(CDK)HMM predict
176Phosphotyrosine(EGFR)HMM predict
206Phosphothreonine(CK2)HMM predict
225O-linkedHMM predict
227PhosphothreonineHMM predict
227Phosphothreonine(MAPK)HMM predict
235O-linkedHMM predict
259Phosphothreonine(PKC)HMM predict
262O-linkedHMM predict
263O-linkedHMM predict
297MethylarginineHMM predict
317N-linkedHMM predict
321N-linkedHMM predict
409Phosphothreonine(PKC)HMM predict
438MethylarginineHMM predict
449MethylarginineHMM predict
457MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012297
  • Location:chr4 76786990-76817341
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 76798120 76798308 188 0
CTCF CD4SISSRdata 76798120 76798308 188 0
CTCF G2GSE9613 76789723 76789996 273 0
CTCF G2GSE9613 76816895 76817741 846 0
H3K4me3 colorectalcancer 76815958 76817148 1190 0
H3ac HepG2E 76815045 76817477 2432 0
PolII HeLaGSE12783 76815753 76818629 2876 0
Rb SenescentGSE19898 76816719 76817214 495 0
TAF HelaGSE8489 76810137 76810652 515 0
TAF HelaGSE8489 76815958 76816939 981 0
hScc1 BcellGSE12603 76816717 76817883 1166 0
p130 QuiescentGSE19898 76816689 76816978 289 0
p130 QuiescentGSE19898 76816992 76817287 295 0
p130 SenescentGSE19898 76816795 76817263 468 0
p130 shRbQuiescentGSE19898 76816630 76817640 1010 0
p130 shRbSenescentGSE19898 76816701 76817109 408 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 16331254
hsa-miR-125a-5p hsa-mir-125a 19 16331254
hsa-miR-195 hsa-mir-195 17 16331254
hsa-miR-195* hsa-mir-195 17 16331254
hsa-miR-200a hsa-mir-200a 1 16331254
hsa-miR-200a* hsa-mir-200a 1 16331254
hsa-miR-224 hsa-mir-224 X 16331254
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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