AutismKB 2.0

Annotation Detail for IQSEC1


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Basic Information Top
Gene Symbol:IQSEC1 ( ARFGEP100,KIAA0763 )
Gene Full Name: IQ motif and Sec7 domain 1
Band: 3p25.2
Quick LinksEntrez ID:9922; OMIM: 610166; Uniprot ID:IQEC1_HUMAN; ENSEMBL ID: ENSG00000144711; HGNC ID: 29112
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
107Phosphoserine (By similarity).
180Phosphoserine.
362Phosphothreonine.
512Phosphoserine.
515Phosphoserine (By similarity).
Location(AA) Modifications Resource
107Phosphoserine (By similarity).Swiss-Prot 53.0
180Phosphoserine (By similarity).Swiss-Prot 53.0
362Phosphothreonine.Swiss-Prot 53.0
362PhosphothreoninePhospho.ELM 6.0
512Phosphoserine (By similarity).Swiss-Prot 53.0
515Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
13Phosphoserine(IKK)HMM predict
13Phosphoserine(PKG)HMM predict
29O-linkedHMM predict
30Phosphoserine(IKK)HMM predict
34O-linkedHMM predict
35O-linkedHMM predict
51O-linkedHMM predict
52O-linkedHMM predict
58Phosphotyrosine(Syk)HMM predict
79Phosphothreonine(PKC)HMM predict
105Phosphoserine(IKK)HMM predict
105Phosphoserine(PKB)HMM predict
105Phosphoserine(PKG)HMM predict
105Phosphoserine(CK1)HMM predict
134Phosphothreonine(PKC)HMM predict
198Phosphoserine(CAMK2)HMM predict
222Phosphothreonine(PKC)HMM predict
225Phosphoserine(CDK)HMM predict
225Phosphoserine(CDC2)HMM predict
225PhosphoserineHMM predict
313Phosphoserine(ATM)HMM predict
319Phosphoserine(ATM)HMM predict
362Phosphothreonine(CDK)HMM predict
364Phosphoserine(CK1)HMM predict
389Phosphoserine(IKK)HMM predict
393Phosphoserine(CK2)HMM predict
400Phosphoserine(CK1)HMM predict
452N-linkedHMM predict
456N-linkedHMM predict
459Phosphoserine(CK1)HMM predict
459O-linkedHMM predict
463Phosphoserine(CK2)HMM predict
465Phosphotyrosine(Syk)HMM predict
465Phosphotyrosine(INSR)HMM predict
465SulfotyrosineHMM predict
466Phosphoserine(ATM)HMM predict
466Phosphoserine(CK1)HMM predict
472Phosphoserine(IKK)HMM predict
474N-linkedHMM predict
478N-linkedHMM predict
480N-linkedHMM predict
484N-linkedHMM predict
494Phosphoserine(CK1)HMM predict
512Phosphoserine(IKK)HMM predict
636S-palmitoylHMM predict
720Phosphoserine(ATM)HMM predict
797Phosphoserine(PKA)HMM predict
801Phosphoserine(IKK)HMM predict
854Phosphothreonine(PKA)HMM predict
886Phosphoserine(PKA)HMM predict
888Phosphoserine(IKK)HMM predict
899N-linkedHMM predict
911Phosphotyrosine(Jak)HMM predict
939Phosphoserine(PKG)HMM predict
940Phosphoserine(PKG)HMM predict
943Phosphoserine(CK1)HMM predict
943Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014869
  • Location:chr3 12914373-12983959
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 13000719 13000987 268 16894
CTCF CD4SISSRdata 13000719 13000987 268 16894
CTCF HelaGSE12889 13000779 13000988 209 16924
CTCF G2GSE9613 12985972 12986148 176 2101
CTCF G2GSE9613 12991334 12991468 134 7442
CTCF G2GSE9613 12992716 12993004 288 8901
CTCF G2GSE9613 12998291 12998559 268 14466
CTCF G2GSE9613 12999021 12999296 275 15199
CTCF G2GSE9613 12999782 13001092 1310 16478
CTCF G2GSE9613 13001638 13001925 287 17822
CTCF G2GSE9613 13003577 13003928 351 19793
Myc K562GSE19551 13000456 13001368 912 16953
Nanog hESGSE18292 12995650 12995919 269 11825
hScc1 BcellGSE12603 12991272 12991876 604 7615
hScc1 BcellGSE12603 13000542 13001055 513 16839
hScc1 BcellGSE12603 13003622 13003928 306 19816
hScc1 CdLSGSE12603 12983688 12984489 801 129
hScc1 G2GSE9613 12999818 13001018 1200 16459
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 12908470 12908761 291 5758
CTCF CD4SISSRdata 12908470 12908761 291 5758
CTCF G2GSE9613 12894631 12894980 349 19568
CTCF G2GSE9613 12901335 12901542 207 12935
CTCF G2GSE9613 12908630 12909253 623 5432
CTCF G2GSE9613 12911860 12912370 510 2259
NRSF JurkatGSE13047 12895741 12896226 485 18390
NRSF JurkatSISSRdata 12895741 12896120 379 18443
NRSF-mono JurkatQuESTdata 12895738 12896185 447 18412
NRSF-poly JurkatQuESTdata 12895778 12896226 448 18372
Nanog hESGSE18292 12908570 12908787 217 5695
Oct1 HelaGSE14283 12899654 12899683 29 14705
Oct1 HelaGSE14283 12906929 12906959 30 7430
hScc1 BcellGSE12603 12907571 12907784 213 6696
hScc1 BcellGSE12603 12908630 12909503 873 5307
hScc1 CdLSGSE12603 12907533 12907784 251 6715
hScc1 CdLSGSE12603 12908630 12909074 444 5522
hScc1 G2GSE9613 12907571 12907784 213 6696
hScc1 G2GSE9613 12908630 12909048 418 5535
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 12918333 12918509 176 0
CTCF G2GSE9613 12914585 12915909 1324 0
CTCF G2GSE9613 12917362 12917854 492 0
CTCF G2GSE9613 12919100 12919485 385 0
CTCF G2GSE9613 12920211 12920959 748 0
CTCF G2GSE9613 12921395 12922345 950 0
CTCF G2GSE9613 12922865 12923142 277 0
CTCF G2GSE9613 12923892 12924597 705 0
CTCF G2GSE9613 12924880 12925629 749 0
CTCF G2GSE9613 12930637 12931628 991 0
CTCF G2GSE9613 12935804 12936287 483 0
CTCF G2GSE9613 12937430 12937972 542 0
CTCF G2GSE9613 12939374 12939578 204 0
CTCF G2GSE9613 12940500 12940715 215 0
CTCF G2GSE9613 12943274 12944129 855 0
CTCF G2GSE9613 12946126 12946818 692 0
CTCF G2GSE9613 12947584 12948581 997 0
CTCF G2GSE9613 12949055 12949908 853 0
CTCF G2GSE9613 12951011 12952046 1035 0
CTCF G2GSE9613 12957258 12957443 185 0
CTCF G2GSE9613 12957724 12958354 630 0
CTCF G2GSE9613 12959795 12960246 451 0
CTCF G2GSE9613 12960974 12961695 721 0
CTCF G2GSE9613 12968259 12968580 321 0
CTCF G2GSE9613 12969172 12969612 440 0
CTCF G2GSE9613 12970572 12971037 465 0
CTCF G2GSE9613 12971287 12971753 466 0
CTCF G2GSE9613 12977212 12977744 532 0
CTCF G2GSE9613 12983113 12984211 1098 0
FOXA1 MCF7GSE15244 12975969 12976627 658 0
FOXA1 MCF7GSE15244 12978617 12980444 1827 0
FOXA1 MCF7GSE15244 12980736 12981056 320 0
FOXA1 MCF7GSE15244 12981366 12982399 1033 0
FoxA1 MCF7MACSdata 12981192 12981578 386 0
H3ac HepG2E 12978043 12978215 172 0
H3ac HepG2E 12981366 12983826 2460 0
Oct1 H2O2-HelaGSE14283 12924233 12924268 35 0
Oct1 H2O2-HelaGSE14283 12927121 12927152 31 0
Oct1 HelaGSE14283 12924097 12924147 50 0
Oct1 HelaGSE14283 12924233 12924269 36 0
RARA MCF7GSE15244 12981366 12982399 1033 0
RARG MCF7GSE15244 12981366 12982435 1069 0
TFAP2C MCF7GSE21234 12930534 12931142 608 0
TFAP2C MCF7GSE21234 12960725 12961368 643 0
TFAP2C MCF7GSE21234 12965063 12966168 1105 0
TFAP2C MCF7GSE21234 12971481 12971951 470 0
hScc1 BcellGSE12603 12920296 12920673 377 0
hScc1 BcellGSE12603 12926146 12926545 399 0
hScc1 BcellGSE12603 12937542 12937972 430 0
hScc1 BcellGSE12603 12941290 12941803 513 0
hScc1 BcellGSE12603 12960938 12961172 234 0
hScc1 BcellGSE12603 12971423 12972071 648 0
hScc1 BcellGSE12603 12977274 12977781 507 0
hScc1 BcellGSE12603 12983113 12984211 1098 0
hScc1 G2GSE9613 12921501 12921961 460 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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