AutismKB 2.0

Annotation Detail for CDC25B


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Basic Information Top
Gene Symbol:CDC25B ( - )
Gene Full Name: cell division cycle 25 homolog B (S. pombe)
Band: 20p13
Quick LinksEntrez ID:994; OMIM: 116949; Uniprot ID:MPIP2_HUMAN; ENSEMBL ID: ENSG00000101224; HGNC ID: 1726
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
12O-linkedHMM predict
12Phosphoserine(IKK)HMM predict
15Phosphoserine(CDC2)HMM predict
15O-linkedHMM predict
42Phosphoserine(CDC2)HMM predict
49O-linkedHMM predict
50Phosphoserine(IKK)HMM predict
50O-linkedHMM predict
50O-linkedHMM predict
53O-linkedHMM predict
72Phosphoserine(IKK)HMM predict
95Phosphoserine(CK2)HMM predict
95Phosphoserine(IKK)HMM predict
95Phosphoserine(PKG)HMM predict
95Phosphoserine(PKA)HMM predict
95Phosphoserine(CAMK2)HMM predict
97Phosphoserine(IKK)HMM predict
98Phosphoserine(CK1)HMM predict
98O-linkedHMM predict
100Phosphoserine(CK1)HMM predict
100Phosphoserine(CK2)HMM predict
103Phosphoserine(CK2)HMM predict
106Phosphoserine(CK1)HMM predict
107Phosphoserine(CK1)HMM predict
115Phosphoserine(CDC2)HMM predict
151Phosphoserine(PKA)HMM predict
151Phosphoserine(PKB)HMM predict
165N-linkedHMM predict
168N-linkedHMM predict
178Phosphoserine(PKA)HMM predict
178Phosphoserine(CAMK2)HMM predict
178Phosphoserine(PKG)HMM predict
178Phosphoserine(IKK)HMM predict
182Phosphoserine(CK2)HMM predict
182Phosphoserine(IKK)HMM predict
187Phosphoserine(CK2)HMM predict
206Phosphothreonine(CDK)HMM predict
230PhosphoserineHMM predict
238Phosphoserine(CDC2)HMM predict
265Phosphothreonine(CK2)HMM predict
321Phosphoserine(CDC2)HMM predict
353Phosphoserine(PKG)HMM predict
353Phosphoserine(IKK)HMM predict
353Phosphoserine(PKA)HMM predict
355Phosphothreonine(PKA)HMM predict
355Phosphothreonine(CDK)HMM predict
355Phosphothreonine(MAPK)HMM predict
414Phosphotyrosine(INSR)HMM predict
425Phosphothreonine(PKC)HMM predict
470Phosphoserine(CDC2)HMM predict
542Phosphotyrosine(EGFR)HMM predict
542Phosphotyrosine(INSR)HMM predict
542Phosphotyrosine(SRC)HMM predict
542Phosphotyrosine(Syk)HMM predict
561Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004358
  • Location:chr20 3724400-3734758
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3740336 3740568 232 5694
CTCF CD4SISSRdata 3740336 3740568 232 5694
H3ac HepG2E 3740774 3740955 181 6106
Myc K562GSE19551 3740396 3740847 451 5863
RARA MCF7GSE15244 3739834 3740955 1121 5636
STAT1 HeLaGSE12783 3735246 3737486 2240 1608
TAF HelaGSE8489 3739834 3740320 486 5319
TFAP2C MCF7GSE21234 3735694 3737300 1606 1739
TFAP2C MCF7GSE21234 3739738 3741038 1300 5630
USF1 HepG2E 3736002 3736893 891 1689
p130 QuiescentGSE19898 3740442 3740852 410 5889
p130 SenescentGSE19898 3740081 3741150 1069 5857
p130 shRbSenescentGSE19898 3740019 3741173 1154 5838
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3730713 3730831 118 0
E2F4 G0GSE7516 3724282 3725139 857 0
H3ac HepG2E 3725381 3727584 2203 0
H3ac HepG2E 3727847 3728583 736 0
KLF4 hESGSE17917 3724985 3725227 242 0
LIN9 G0GSE7516 3724044 3726139 2095 0
LIN9 SGSE7516 3724044 3724845 801 0
Rb GrowingGSE19898 3724536 3724934 398 0
Rb SenescentGSE19898 3724467 3724684 217 0
Rb SenescentGSE19898 3724700 3725067 367 0
TFAP2C MCF7GSE21234 3724253 3725160 907 0
hScc1 BcellGSE12603 3724282 3725490 1208 0
hScc1 BcellGSE12603 3726104 3726653 549 0
p130 QuiescentGSE19898 3724423 3725066 643 0
p130 SenescentGSE19898 3724305 3724560 255 0
p130 SenescentGSE19898 3724572 3725060 488 0
p130 shRbQuiescentGSE19898 3724358 3725013 655 0
p130 shRbSenescentGSE19898 3724332 3725067 735 0
p130 G0GSE7516 3724204 3725103 899 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018