AutismKB 2.0

Annotation Detail for CDC27


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Basic Information Top
Gene Symbol:CDC27 ( ANAPC3,APC3,CDC27Hs,D0S1430E,D17S978E,HNUC )
Gene Full Name: cell division cycle 27 homolog (S. cerevisiae)
Band: 17q21.32
Quick LinksEntrez ID:996; OMIM: 116946; Uniprot ID:CDC27_HUMAN; ENSEMBL ID: ENSG00000004897; HGNC ID: 1728
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
205Phosphothreonine.
209Phosphothreonine.
244Phosphothreonine.
291Phosphoserine.
313Phosphothreonine.
339Phosphoserine.
366Phosphothreonine.
426Phosphoserine.
430Phosphothreonine.
435Phosphoserine.
438Phosphoserine.
446Phosphothreonine.
Location(AA) Modifications Resource
205Phosphothreonine.Swiss-Prot 53.0
205Phosphothreonine (CDK1)Phospho.ELM 6.0
209Phosphothreonine (PLK1)Phospho.ELM 6.0
209Phosphothreonine.Swiss-Prot 53.0
222Phosphoserine (CDK1)Phospho.ELM 6.0
244Phosphothreonine.Swiss-Prot 53.0
244PhosphothreoninePhospho.ELM 6.0
289Phosphothreonine (CDK1)Phospho.ELM 6.0
291Phosphoserine.Swiss-Prot 53.0
291PhosphoserinePhospho.ELM 6.0
296PhosphoserinePhospho.ELM 6.0
312Phosphoserine (CDK1)Phospho.ELM 6.0
313Phosphothreonine.Swiss-Prot 53.0
313PhosphothreoninePhospho.ELM 6.0
329Phosphothreonine (CDK1)Phospho.ELM 6.0
343Phosphothreonine (CDK1)Phospho.ELM 6.0
364Phosphoserine (CDK1)Phospho.ELM 6.0
366Phosphothreonine (CDK1)Phospho.ELM 6.0
426Phosphoserine (CDK1;PLK1)Phospho.ELM 6.0
426Phosphoserine.Swiss-Prot 53.0
430Phosphothreonine (PLK1)Phospho.ELM 6.0
430Phosphothreonine.Swiss-Prot 53.0
434Phosphoserine (PLK1)Phospho.ELM 6.0
435Phosphoserine.Swiss-Prot 53.0
435Phosphoserine (CDK1;PLK1)Phospho.ELM 6.0
438PhosphoserinePhospho.ELM 6.0
438Phosphoserine.Swiss-Prot 53.0
446Phosphothreonine (CDK1;PLK1)Phospho.ELM 6.0
446Phosphothreonine.Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphotyrosine(Abl)HMM predict
37Phosphoserine(CK1)HMM predict
79S-palmitoylHMM predict
175N-linkedHMM predict
178N-linkedHMM predict
190N-linkedHMM predict
222Phosphoserine(CK1)HMM predict
264Phosphothreonine(PKC)HMM predict
276Phosphoserine(CDK)HMM predict
276Phosphoserine(CDC2)HMM predict
291O-linkedHMM predict
300N-linkedHMM predict
303N-linkedHMM predict
312O-linkedHMM predict
334Phosphoserine(CK1)HMM predict
349O-linkedHMM predict
352O-linkedHMM predict
356O-linkedHMM predict
357O-linkedHMM predict
358O-linkedHMM predict
364Phosphoserine(CDK)HMM predict
364Phosphoserine(CDC2)HMM predict
368O-linkedHMM predict
369Phosphoserine(CDC2)HMM predict
383Phosphothreonine(PKC)HMM predict
388Phosphothreonine(CK2)HMM predict
443Phosphoserine(PKG)HMM predict
515Phosphotyrosine(EGFR)HMM predict
515Phosphotyrosine(SRC)HMM predict
515Phosphotyrosine(INSR)HMM predict
803Phosphoserine(ATM)HMM predict
803Phosphoserine(IKK)HMM predict
806Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001256
  • Location:chr17 42552624-42621663
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 42621381 42622174 793 114
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 42546477 42546906 429 5933
Fos K562GSE19551 42532329 42533124 795 19898
Nanog hESGSE18292 42552236 42552707 471 153
Oct1 H2O2-HelaGSE14283 42545061 42545088 27 7550
Oct1 HelaGSE14283 42548177 42548210 33 4431
hScc1 CdLSGSE12603 42537803 42538050 247 14698
p130 SenescentGSE19898 42532651 42532881 230 19859
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 42604223 42604444 221 0
H3K4me2 HCT116GSE10453 42620560 42621133 573 0
H3K4me3 colorectalcancer 42620560 42621752 1192 0
H3ac HepG2E 42620382 42622486 2104 0
IGF1R DFBGSE23792 42604145 42604529 384 0
Myc K562GSE19551 42576186 42576368 182 0
Myc K562GSE19551 42604241 42604537 296 0
Myc K562GSE19551 42613824 42614072 248 0
Myc hESGSE17917 42621358 42621755 397 0
NRSF-mono JurkatQuESTdata 42589241 42589453 212 0
NRSF-mono JurkatQuESTdata 42590511 42590724 213 0
NRSF-mono JurkatQuESTdata 42602251 42602403 152 0
Nanog ESGSE20650 42604293 42604461 168 0
Nanog ESGSE20650 42613912 42614053 141 0
Oct1 H2O2-HelaGSE14283 42553228 42553254 26 0
Oct1 H2O2-HelaGSE14283 42580715 42580748 33 0
Oct1 HelaGSE14283 42573818 42573849 31 0
Oct1 HelaGSE14283 42592336 42592380 44 0
Oct4 ESGSE20650 42589278 42589522 244 0
Oct4 ESGSE20650 42604277 42604448 171 0
Oct4 ESGSE20650 42613920 42614113 193 0
Oct4 ESGSE20650 42621400 42621757 357 0
PHF8 Hs68minusFBSGSE20725 42620826 42622020 1194 0
Pol3 K562GSE19551 42604177 42604498 321 0
RARG MCF7GSE15244 42620961 42621318 357 0
TAF k562GSE8489 42620560 42622713 2153 0
hScc1 BcellGSE12603 42621354 42621752 398 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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