AutismKB 2.0

Annotation Detail for USP3


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Basic Information Top
Gene Symbol:USP3 ( MGC129878,MGC129879,SIH003,UBP )
Gene Full Name: ubiquitin specific peptidase 3
Band: 15q22.3
Quick LinksEntrez ID:9960; OMIM: 604728; Uniprot ID:UBP3_HUMAN; ENSEMBL ID: ENSG00000140455; HGNC ID: 12626
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
141Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
21N-linkedHMM predict
26Phosphoserine(IKK)HMM predict
32S-palmitoylHMM predict
34Phosphoserine(IKK)HMM predict
35N-linkedHMM predict
61Phosphotyrosine(Syk)HMM predict
104N-linkedHMM predict
139N-linkedHMM predict
143N-linkedHMM predict
150N-linkedHMM predict
238Phosphoserine(CDC2)HMM predict
238Phosphoserine(MAPK)HMM predict
384Phosphotyrosine(Jak)HMM predict
384Phosphotyrosine(INSR)HMM predict
428Phosphotyrosine(EGFR)HMM predict
448Phosphoserine(CK1)HMM predict
487N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006537
  • Location:chr15 61583862-61670711
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61566557 61566901 344 17134
CTCF CD4SISSRdata 61566557 61566901 344 17134
CTCF JurkatGSE12889 61566615 61566810 195 17150
CTCF G2GSE9613 61566582 61566905 323 17119
FoxA1 MCF7MACSdata 61581395 61581567 172 2382
H3ac HepG2E 61582553 61583502 949 835
PHF8 293TGSE20725 61583150 61584410 1260 83
TAF HelaGSE8489 61581973 61583391 1418 1181
TFAP2C MCF7GSE21234 61580556 61580910 354 3130
TFAP2C MCF7GSE21234 61582267 61583531 1264 964
hScc1 BcellGSE12603 61566461 61566905 444 17180
hScc1 BcellGSE12603 61576732 61577053 321 6970
hScc1 BcellGSE12603 61582420 61585088 2668 109
hScc1 CdLSGSE12603 61566385 61566905 520 17218
p130 shRbQuiescentGSE19898 61582533 61583442 909 875
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 61666513 61667168 655 0
CTCF G2GSE9613 61584012 61584434 422 0
FoxA1 MCF7MACSdata 61666837 61667142 305 0
H3K4me3 colorectalcancer 61585206 61585571 365 0
H3ac HepG2E 61584837 61586272 1435 0
Myc K562GSE19551 61603479 61604247 768 0
Nanog ESGSE20650 61638987 61639442 455 0
Nanog hESGSE18292 61639076 61639441 365 0
P300 T0-glioblastomaGSE21026 61666397 61667558 1161 0
P300 T30-glioblastomaGSE21026 61666433 61667419 986 0
PHF8 HeLaGSE20725 61582900 61584886 1986 0
Rb SenescentGSE19898 61584420 61584723 303 0
TAF HelaGSE8489 61584633 61586088 1455 0
TAF HelaGSE8489 61609896 61610419 523 0
hScc1 CdLSGSE12603 61583148 61585351 2203 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8931 mRNA USP3 chr15 61583862 61670714 301 mRNA chr15 61667185 61680061Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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